Navigation Links
Sublingual immunotherapy for inhalant allergies deserves deeper consideration
Date:4/29/2009

Alexandria, VA Sublingual immunotherapy for the treatment of allergy symptoms caused by a wide variety of environmental inhalants has been effectively used in Europe. It should be employed to further treatment of allergies in the United States, where allergic symptoms are largely undertreated, according to an invited article in the April 2009 issue of Otolaryngology-Head and Neck Surgery. A response to the article, published in the same journal issue, expresses cautious optimism, but calls for additional research.

Sublingual immunotherapy (SLIT) involves the administering of an allergen solution under the tongue, which in time reduces the patient's sensitivity to those allergens. The more prevalent alternative is subcutaneous immunotherapy, usually administered through an injection.

The authors of the invited article note that despite allergic symptoms contributing heavily to poor quality of life, high socioeconomic costs, and increased health issues, these syndromes remain underdiagnosed and undertreated. The authors attribute this to a public attitude that trivializes allergic conditions, along with patients' general dissatisfaction with the conventional pharmacy-based ways of treating allergic conditions. They conclude that the extensive implementation of SLIT treatment in Europe has proven to overcome these shortcomings in reaching patients, and the treatment is supported with significant literature documenting its efficacy, along with extensive clinical experience.

In a response to the invited article, AAO-HNSF Board of Directors member John H. Krouse, MD, PhD, recognizes the promising data associated with SLIT treatment, but urges caution until several issues can be addressed. Specifically, Dr. Krouse offers five areas of concern with SLIT treatment: patient selection; pattern of sensitization; dosing, preparation, and delivery; safety; and the financial cost of therapy. He concludes by noting the existence of a gap in allergy management in the United States, and the promise SLIT treatment holds, if carefully evaluated, in reaching these unaddressed segments of the population.

Allergy symptoms appear when the immune system reacts to an allergic substance that enters the body as though it is an unwelcomed invader. The immune system will produce special antibodies capable of recognizing the same allergen if it enters the body at a later time.

When an allergen reenters the body, the immune system rapidly recognizes it, causing a series of reactions. These reactions often involve tissue destruction, blood vessel dilation, and production of many inflammatory substances, including histamine. Histamine produces common allergy symptoms such as itchy, watery eyes, nasal and sinus congestion, headaches, sneezing, scratchy throat, hives, and shortness of breath, among others. Other less common symptoms are balance disturbances, skin irritations such as eczema, and even respiratory problems like asthma.


'/>"/>

Contact: Matt Daigle
newsroom@entnet.org
703-535-3754
American Academy of Otolaryngology -- Head and Neck Surgery
Source:Eurekalert

Related medicine news :

1. A Few Shots Away: Immunotherapy May Relieve Allergy Symptoms
2. Oral Allergy Immunotherapy Helps Control Asthma
3. Radioimmunotherapy After Chemo Safe for Common Lymphoma
4. Immunotherapy: enlisting the immune system to fight cancer
5. FDA Says, Wait To Dying Men; Coast-To-Coast Prostate Cancer Demonstrations on May 30th in Protest of FDA Failure to Approve Safe, Effective Immunotherapy
6. Dangerous Side Effect Found in Cancer Immunotherapy Research
7. Latest research on allergies: Specific immunotherapy can help
8. OHSU Cancer Institute researcher: radiation, immunotherapy gives greater effectiveness
9. Educational Symposium to Present Panel Discussion on Melanoma Treatments and Immunotherapy
10. Towards improved immunotherapy
11. MaxCyte to Present Targeted Cancer Immunotherapy Product at 50th Annual Meeting of the American Society of Hematology
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:10/13/2017)... , ... October 13, 2017 , ... As health professionals ... known as “patient engagement.” The patient is doing more than filling out a survey; ... , “There is an increasing emphasis in health care and research on the importance ...
(Date:10/13/2017)... Nevada (PRWEB) , ... October 13, 2017 , ... ... Hemp CBD Oil utilizing Purzorb™ technology. Applying the Purzorb™process to full spectrum CBD oil ... required and providing a CBD form that can be easily incorporated into liquid products, ...
(Date:10/13/2017)... ... October 13, 2017 , ... Many families have long-term ... long-term care insurance companies have a waiver for care if the client has a ... when the family pays for care, is often waived, so the benefits from their ...
(Date:10/13/2017)... ... 13, 2017 , ... Yisrayl Hawkins, Pastor and Overseer at The House of ... popular and least understood books in the Holy Scriptures, Revelation. The Book of Revelation ... scholars for centuries. Many have tossed it off as mere rubbish, but Yisrayl Hawkins ...
(Date:10/13/2017)... ... , ... “America On The Brink”: the Christian history of the United States ... creation of published author, William Nowers. Captain Nowers and his wife, Millie, have ... thirty years in the Navy. Following his career as a naval aviator and ...
Breaking Medicine News(10 mins):
(Date:10/5/2017)... , Oct. 5, 2017  In response to ... Oral and Maxillofacial Surgeons (AAOMS) released prescribing recommendations ... to be used as a first-line therapy to ... Recognizing the value ... White Paper "Opioid Prescribing: Acute and Postoperative Pain ...
(Date:10/2/2017)... -- Eli Lilly and Company (NYSE: LLY ) ... of 2017 on Tuesday, October 24, 2017. Lilly will ... the investment community and media to further detail the ... begin at 9 a.m. Eastern time. Investors, media and ... the conference call through a link that will be ...
(Date:9/28/2017)... Sept. 28, 2017 Cohen Veterans Bioscience and ... use of wearable and home sensors for real-time monitoring ... Signal Foundation, a nonprofit organization focused on disruptive health ... an affordable analytical system to record and integrate behavioral, ... ...
Breaking Medicine Technology: