Navigation Links
Sublingual immunotherapy for inhalant allergies deserves deeper consideration
Date:4/29/2009

Alexandria, VA Sublingual immunotherapy for the treatment of allergy symptoms caused by a wide variety of environmental inhalants has been effectively used in Europe. It should be employed to further treatment of allergies in the United States, where allergic symptoms are largely undertreated, according to an invited article in the April 2009 issue of Otolaryngology-Head and Neck Surgery. A response to the article, published in the same journal issue, expresses cautious optimism, but calls for additional research.

Sublingual immunotherapy (SLIT) involves the administering of an allergen solution under the tongue, which in time reduces the patient's sensitivity to those allergens. The more prevalent alternative is subcutaneous immunotherapy, usually administered through an injection.

The authors of the invited article note that despite allergic symptoms contributing heavily to poor quality of life, high socioeconomic costs, and increased health issues, these syndromes remain underdiagnosed and undertreated. The authors attribute this to a public attitude that trivializes allergic conditions, along with patients' general dissatisfaction with the conventional pharmacy-based ways of treating allergic conditions. They conclude that the extensive implementation of SLIT treatment in Europe has proven to overcome these shortcomings in reaching patients, and the treatment is supported with significant literature documenting its efficacy, along with extensive clinical experience.

In a response to the invited article, AAO-HNSF Board of Directors member John H. Krouse, MD, PhD, recognizes the promising data associated with SLIT treatment, but urges caution until several issues can be addressed. Specifically, Dr. Krouse offers five areas of concern with SLIT treatment: patient selection; pattern of sensitization; dosing, preparation, and delivery; safety; and the financial cost of therapy. He concludes by noting the existence of a gap in allergy management in the United States, and the promise SLIT treatment holds, if carefully evaluated, in reaching these unaddressed segments of the population.

Allergy symptoms appear when the immune system reacts to an allergic substance that enters the body as though it is an unwelcomed invader. The immune system will produce special antibodies capable of recognizing the same allergen if it enters the body at a later time.

When an allergen reenters the body, the immune system rapidly recognizes it, causing a series of reactions. These reactions often involve tissue destruction, blood vessel dilation, and production of many inflammatory substances, including histamine. Histamine produces common allergy symptoms such as itchy, watery eyes, nasal and sinus congestion, headaches, sneezing, scratchy throat, hives, and shortness of breath, among others. Other less common symptoms are balance disturbances, skin irritations such as eczema, and even respiratory problems like asthma.


'/>"/>

Contact: Matt Daigle
newsroom@entnet.org
703-535-3754
American Academy of Otolaryngology -- Head and Neck Surgery
Source:Eurekalert

Related medicine news :

1. A Few Shots Away: Immunotherapy May Relieve Allergy Symptoms
2. Oral Allergy Immunotherapy Helps Control Asthma
3. Radioimmunotherapy After Chemo Safe for Common Lymphoma
4. Immunotherapy: enlisting the immune system to fight cancer
5. FDA Says, Wait To Dying Men; Coast-To-Coast Prostate Cancer Demonstrations on May 30th in Protest of FDA Failure to Approve Safe, Effective Immunotherapy
6. Dangerous Side Effect Found in Cancer Immunotherapy Research
7. Latest research on allergies: Specific immunotherapy can help
8. OHSU Cancer Institute researcher: radiation, immunotherapy gives greater effectiveness
9. Educational Symposium to Present Panel Discussion on Melanoma Treatments and Immunotherapy
10. Towards improved immunotherapy
11. MaxCyte to Present Targeted Cancer Immunotherapy Product at 50th Annual Meeting of the American Society of Hematology
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:2/26/2017)... ... February 26, 2017 , ... IndustryArchive.Org . is announcing ... B2B Marketing. B2B Sellers will now only pay for B.A.N.T. quality sales leads based ... of IndustryArchive.Org, said, “Given the new reality that B2B buyers are controlling the sales ...
(Date:2/26/2017)... ... 2017 , ... ODH, Inc.™ announced today it will exhibit and speak ... City Hotel in Arlington, VA. ODH’s director of medical strategy, Candace Saldarini, M.D., will ... Medicaid population health management. , ODH will also have an exhibit booth where attendees ...
(Date:2/26/2017)... ... 2017 , ... Occupational pesticide exposure is linked to an ... according to a study released today at the 1st Pan American Parkinson’s and ... pesticides and incidence of sporadic PD through occupational exposure. This latest study, led ...
(Date:2/24/2017)... ... February 24, 2017 , ... HealthPostures, expert ... Core benefits and advantages built into the home office sit stand solution are ... feel. Ability to gain the benefits embedded in the TaskMate Go are available ...
(Date:2/24/2017)... ... ... two months after the official release of The Private Collection – Edition 2017 at ... a second print-run of its lavish luxury travel coffee table book. , An ... at more than six kilos, retails at EUR 1,000 per copy and is packed ...
Breaking Medicine News(10 mins):
(Date:2/24/2017)... , Australien, 24. Februar 2017 ITL ... Unternehmen des Gesundheitsbereiches, ist erfreut, für das zum ... dem entsprechenden Vorjahreszeitraum exzellente Ergebnisse vorlegen zu können. ... Aktualisierung zum Wachstum" finden Sie hier . ... Gewinn nach Steuern 2,12 Millionen USD (Dez. 2015: 1,04 Millionen USD; +104 %) ...
(Date:2/24/2017)... 2017  Directors from Pharma To Market Pty Ltd and Ador ... resulting in the founding of Pharma To Market Pte Ltd, based ... are pleased to announce their expansion into Asia ... . The company are delighted to appoint Joelle Chia ... Singapore based entity. Joelle brings with her an ...
(Date:2/24/2017)... 2017 Non-alcoholic steatohepataitis (NASH) Pipeline ... drugs being developed for the treatment of ... that are in various phases of development ... on novel pharmacologic drugs & regenerative medicines ... recombinant proteins and RNA-based therapeutics, but excludes ...
Breaking Medicine Technology: