Navigation Links
Study uncovers novel genetic variation linked to increased risk of sudden cardiac arrest
Date:6/30/2011

LOS ANGELES June 30, 2011 A study by a global consortium of physician-scientists has identified a genetic variation that may predispose people to double the risk of having a sudden cardiac arrest, a disorder that gives little warning and is fatal in about 95 percent of cases. Although previous, smaller studies have identified some genes with a potential association with sudden cardiac arrest, this is the first study large enough to enable scientists to apply results to the general population. Findings are published today by the Public Library of Science (PloS Genetics).

"We are at the beginning of unraveling the mystery of what causes sudden cardiac arrest and how to prevent it," said senior author Sumeet S. Chugh, MD, associate director of the Cedars-Sinai Heart Institute and a specialist in cardiac electrophysiology. "If we wait until someone has a sudden cardiac arrest, it is usually too late for treatment. That is why knowing who is genetically susceptible is so important."

Unlike heart attacks (myocardial infarction), which are typically caused by clogged coronary arteries reducing blood flow to the heart muscle, sudden cardiac arrest is the result of defective electrical impulses. Patients may have little or no warning, and the disorder usually causes nearly instantaneous death. Every year, 250,000 to 300,000 people in the U.S. and up to 5 million worldwide die from sudden cardiac arrest.

Despite years of significant advances in emergency medicine and resuscitation, just five percent of those who suffer sudden cardiac arrest survive. For patients at known risk for this or other heart rhythm abnormalities, an implantable cardioverter-defibrillator (ICD) may be placed in the chest or abdomen to detect faulty electrical impulses and provide a shock to return normal rhythm. Better genetic predictors of risk may someday enable the accurate prediction of which patients are most likely to benefit from costly ICD the
'/>"/>

Contact: Sally Stewart
Sally.stewart@cshs.org
310-248-6566
Cedars-Sinai Medical Center
Source:Eurekalert

Page: 1 2

Related medicine news :

1. BMC conducts high rates of thyroid testing in pregnant women, study finds
2. Cotton Swabs Help Prevent Surgical Site Infections: Study
3. Wake Forest Baptist conducts clinical study for insomnia using new technology
4. E-Prescribing Doesnt Slash Errors, Study Finds
5. Study on football: Women get up faster
6. Obesity a Major Cause of Early Death in Women: Study
7. Rutgers study: Third of N.J. immigrant children, many adult newcomers lack health insurance
8. Workplace mental health disability leave recurs sooner than physical health leave, CAMH study shows
9. Preventing Type 2 Diabetes Saves Money: Study
10. Flu Shots for Pregnant Women Also Protect Newborns, Study Finds
11. Certain Cancer Drugs Dont Interfere With Flu Vaccine: Study
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:5/23/2015)... On May 16, the team at Farrell’s eXtreme Bodyshaping ... obstacle run that raised funds for multiple sclerosis. , ... reason we participated was to support people living with MS ... Bodyshaping. “One-hundred percent of the funds raised go to benefit ... only attended by eXtreme Bodyshaping staff, but members of the ...
(Date:5/23/2015)... Injury lawyer Steven H. Heisler commented today on the ... legislature but which has not been signed to date by ... 449 with overwhelming bipartisan support on April 10, 2015, ... This bill ensures that fracking is prohibited in Maryland through ... of fracking to our water supplies and the air we ...
(Date:5/22/2015)... May 22, 2015 River Valley Health ... Johnson, the health system’s Chief Financial Officer (CFO), will ... has served as the company CFO since 2011. , ... be joining the health system as CFO. Wesley will ... basis, while the Board of Trustees conducts a formal ...
(Date:5/22/2015)... NY (PRWEB) May 22, 2015 Hands ... that June 17, 2015, the Annual One Day Sale ... Since 2007, Hands On HCMT offers drastically reduced certificates one ... and estheticians have enough sessions, through what used to be ... is wonderful for the community as well. This once a ...
(Date:5/22/2015)... Memorial Day weekend is typically considered the beginning ... some tips to help promote safe travel. , According to ... traffic fatalities this Memorial Day weekend. Amica is sharing the ... Association: , , Always wear a ... seatbelt, whether they’re driving or riding along as a passenger. ...
Breaking Medicine News(10 mins):Health News:Farrell’s eXtreme Bodyshaping Team Runs through the Muck for MS 2Health News:Baltimore Attorney Urges Governor Hogan to Sign the Fracking Moratorium Bill 2Health News:Baltimore Attorney Urges Governor Hogan to Sign the Fracking Moratorium Bill 3Health News:River Valley Health Partners Announces CFO Transition, Appointment of Interim CFO 2Health News:Hands On HealthCare Massage Therapy & Wellness Day Spa Announces Their Eighth Annual One Day Sale on Gift Certificates Will Take Place on June 17, 2015 2Health News:Hands On HealthCare Massage Therapy & Wellness Day Spa Announces Their Eighth Annual One Day Sale on Gift Certificates Will Take Place on June 17, 2015 3Health News:Amica Has 4 Road Safety Tips for Memorial Day Weekend 2
... dozen people have taken ill and have been hospitalized in ... ‘ baseless’ by spokesman Xiong Yuanda of the Health Bureau ... infectious ‘unknown’ disease, doing the rounds in the city, as ... bureau has sought to dispel reports carried by a famous ...
... across the world have breast implants done for augmentation purposes ... direction, eminent plastic surgeons// have united to offer services in ... comes at an economical rate compared to the so called ... life. The doctors involved are all a highly creditable force ...
... skin patch to treat Alzheimer’s. This research was carried ... these researchers, the skin patch is simpler than the ... occur when a protein called beta amyloid forms many ... skin attacks beta amyloid and breaks it. The current ...
... a tough call between human rights and a medical problem ... ,Jerome Singh and colleagues from Durban's Centre for the AIDS ... for forcible detention and isolation of those affected with XDR-TB. ... that the disease may swamp the whole of South Africa ...
... elders in hospitals and care homes are not being properly attended ... are said to be in hunger// for most of the time. ... ,Commencing the ‘Dignity for older people’ campaign Mr. Lewis said that ... understood. When the food is kept far from an old person ...
... outbreak in the Sydney CBD is linked to the Royal ... suspect//. However, they could not confirm the link. ... bacteria belonging to the Legionella family, Legionella pneumophilia, have been ... in the Circular Quay area on New Year's Eve. ...
Cached Medicine News:Health News:Forcible Detention and Isolation Needed for XDR-TB Patients, warn Experts 2
(Date:5/22/2015)... 2015 The North American dental lasers ... estimated to reach $90.7 million by 2019, at a CAGR ... the TOC of North America Dental Lasers Market for an ... various tables and figures. http://www.micromarketmonitor.com/market/north-america-dental-lasers-1771208223.html ... report.   Dental lasers are specifically used ...
(Date:5/22/2015)... and KING OF PRUSSIA, Pa. ... (NHF) has awarded CSL Behring its 2015 ... unwavering commitment to advancing science and improving the care of ... Paul Perreault , CEO and Managing Director, CSL Limited, during ... City on May 21. "The National ...
(Date:5/22/2015)... According to a new market ... Instruments, Services), by Test Type (Indirect, Enzyme-based, Reactive Oxygen ... End Users - Global Forecast to 2020", published by ... reach $736.85 Million by 2020 from $452.36 Million in ... Browse 71 market data Tables and 90 Figures ...
Breaking Medicine Technology:North America Dental Lasers Market is Expected to Reach $90.7 Million by 2019, at a CAGR of 9.2% From 2014 to 2019 2North America Dental Lasers Market is Expected to Reach $90.7 Million by 2019, at a CAGR of 9.2% From 2014 to 2019 3National Hemophilia Foundation Honors CSL Behring with Corporate Leadership Award 2National Hemophilia Foundation Honors CSL Behring with Corporate Leadership Award 3National Hemophilia Foundation Honors CSL Behring with Corporate Leadership Award 4Oxidative Stress Assays Market Worth $736.85 Million by 2020 2Oxidative Stress Assays Market Worth $736.85 Million by 2020 3Oxidative Stress Assays Market Worth $736.85 Million by 2020 4
... 2011 Milestone Scientific Inc. (OTCQB: MLSS), the recognized leader ... the year ended December 31, 2010. Financial ... Ended December 31, 2009: Total revenues were ... the U.S. decreased 16% to $4.53 million from $5.28 million. ...
... 4, 2011 MonoSol Rx, the developers of PharmFilm® ... pharmaceutical film products, today announced that it has been ... Patent and Trademark Office (USPTO). The patent provides intellectual ... preparation along with the incorporation of specific drugs and ...
Cached Medicine Technology:Milestone Scientific Announces 2010 Year End Results 2Milestone Scientific Announces 2010 Year End Results 3Milestone Scientific Announces 2010 Year End Results 4Milestone Scientific Announces 2010 Year End Results 5Milestone Scientific Announces 2010 Year End Results 6MonoSol Rx Issued Strategic US Patent Governing the Production of Pharmaceutical Films Containing Specific Drugs and Drug Classes 2MonoSol Rx Issued Strategic US Patent Governing the Production of Pharmaceutical Films Containing Specific Drugs and Drug Classes 3
... steroid produced in the adrenal gland and ... except as a precursor molecule. In the ... cortisol by the sequential actions of 21-hyroxylase ... and ovaries, 17alpha-OH-P can be converted to ...
... PC1200 Platelet Incubators bring precise ... counter top. These compact units ... have the security of a ... taking up a large amount ...
The PC4200i is the largest capacity platelet incubator available. It features a built-in agitator with a capacity of 396 random bags (132 apheresis)....
... Platelet incubators hold rotators and ... temperature can be set at ... 15C to 40C (59F to ... from top to bottom. Recorder ...
Medicine Products: