Navigation Links
Study uncovers new cells in the urethra which may detect hazardous substances
Date:3/15/2013

Arnhem, 11 March 2013- A recent study conducted by a group of German scientists revealed the presence of a previously unknown cell in the urethra of mice. These chemosensory cholinergic brush cells are in close contact to sensory neurons that express cholinergic receptors.

The authors suggest that in analogy to brush cells of the respiratory tract, the urethral brush cells may also serve as sentinels being able to detecting hazardous substances and preventing their further retrograde ingression.

The results of this investigation will be presented at the upcoming 28th Annual EAU Congress which will kick off this Friday in Milan. The study won 2nd Prize for Best Abstract in Non-Oncology.

"Urinary tract infections rate among the most common indispositions among out- as well as in-patients and are chiefly triggered by bacteria entering the body through the urethra. We here discovered a previously not recognised cell which surveils this portal of entry," commented the presenting author of the study, Ms. Katharina Filipski of the Anatomy and Cell Biology Department at Justus-Liebig-University Giessen in Germany.

"A further exploration of this cell population will provide insight into cellular interaction and defensive measures against pathogens."

According to the authors, cholinergic chemoceptive cells might play an essential role in detecting and defending microorganisms invading the body through the urethra. The maintenance and support of their protective function could fortify the immune barrier and prevent urinary tract infections by initiating avoiding reflexes as micturition.

"It is also conceivable that dysfunction of this system might result in inappropriate urge, thereby being linked to overactive bladder," explained Ms. Filipski.

During the study, the detection and characterisation of chemosensory brush cells of the murine urethra was addressed by means of ultrastructural immunohistochemistry,
'/>"/>

Contact: Ivanka Moerkerken
i.moerkerken@uroweb.org
31-026-389-0680
European Association of Urology
Source:Eurekalert

Page: 1 2

Related medicine news :

1. Surgery is superior to radiotherapy in men with localized PCa, says prize-winning Swedish study
2. New study on UTIs suggests flagellin is key in stimulating bodys natural defences
3. Japanese P2 study shows potential of combined vaccine and steroid drug in castration resistant PCa
4. Study shows additional role for abiraterone in blocking tumor growth in CRPC
5. Study: 15% of Children Ages 10 - 14 Consider Using Steroids; polyDNA Recommends Muxscle for Safe Muscle Building
6. Blacks With Kidney Disease Should Watch for Blood Pressure Shifts: Study
7. Study of dragonfly prey detection at MBL wins PNAS Cozzarelli Prize
8. Study shows how vitamin E can help prevent cancer
9. Autism Speaks trailblazer study -- Blocking cell distress signals can ease autism symptoms
10. Clot Buster Safe for Stroke Patients on Blood Thinners: Study
11. Study: Dynamic new software improves care of aging brain
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:1/22/2015)... January 23, 2015 AngelWeddingDress, the premier ... 2015 maternity wedding dresses. View website of ... looking for maternity wedding dresses online for a bridal ... with high quality for them. Its maternity wedding dresses ...
(Date:1/22/2015)... Autocarinsurancebest.com has released a new blog post explaining the main ... , Auto insurance quotes help many drivers find the ... to call an agent or visit an agency for price ... website: http://autocarinsurancebest.com/ . , Every business who relies heavily ...
(Date:1/22/2015)... Jolla, Calif. (PRWEB) January 22, 2015 ... Assemblymembers Susan Bonilla (D-Concord) and Kristin Olsen (R-Modesto) ... for their leadership in advancing biotechnology, biomedical science, ... Bonilla and Olsen each received the “2014 Life ...
(Date:1/22/2015)... Mass. (PRWEB) January 22, 2015 EBSCO ... (AMA) are expanding their relationship in an effort to ... around the world. While EBSCO has long made AMA journals ... a sales agent for The JAMA Network. , ...
(Date:1/22/2015)... Step into a macabre world where plants hold ... Wicked Plants, the Museum’s latest featured exhibition, opens Saturday, ... and diabolical plants inside of a dilapidated, Victorian home. ... physical and neurological processes between botanicals and the human ...
Breaking Medicine News(10 mins):Health News:AngelWeddingDress Has Recently Released Its Collection Of 2015 Maternity Wedding Dresses 2Health News:Commercial Auto Insurance Provides Several Important Features! 2Health News:California Biomedical Community Honors Senator Holly Mitchell, Assemblymembers Susan Bonilla & Kristin Olsen 2Health News:California Biomedical Community Honors Senator Holly Mitchell, Assemblymembers Susan Bonilla & Kristin Olsen 3Health News:EBSCO Expands Partnership with the American Medical Association 2Health News:EBSCO Expands Partnership with the American Medical Association 3Health News:EBSCO Expands Partnership with the American Medical Association 4Health News:Wicked Plants are taking over the Science Museum of Virginia 2
... principle to enable the smooth transfer of microorganisms and ... encouraging sign for Indian bioscience. But slow implementation of ... scheme to become the global hub of contract research ... a major player. , ,Discussions in mid-June between ...
... Smoking ban around the world can be materialized by increasing ... enforcing current regulations that prevent or delay youth smoking according ... to improve the lives of billions of people addicted to ... suggestion and act accordingly., , “Our research shows that ...
... people worldwide are estimated to suffer from multiple sclerosis ... in young adults, and has a significant impact on ... afford an average reduction in relapse rates of 30% ... daily to weekly., ,Data from the extension of ...
... of a bird flu pandemic has created a stir worldwide ... and urging vaccine developers to speed up the process of ... ,Representatives of more than 80 countries and international organizations met ... flu pandemic. Health officials including those from the World Health ...
... to inform you of his/her HIV status, but as far ... this. Even horrifying is the fact that you have to ... from the virus., ,The Wellington District Court, New Zealand, ... was charged with criminal nuisance after not disclosing to his ...
... have been held against, a London based leading drug ... anti-asthmatic drug, Serevent to the U.S. Food and Drug ... up for a review. This became evident last November ... needed additional warnings. , ,The Public Citizen Group ...
Cached Medicine News:Health News:Biologicals Transfer Proposal between US and Indian Biotechnology 2Health News:Lawmakers alerted on new tobacco control policies by research team 2Health News:New Hope For Patients With Relapsing Multiple Sclerosis 2Health News:Ruling On Non Disclosure Of HIV Positive Status Is Not Ethical 2Health News:FDA Mislead On Asthma Drug By GlaxoSmithKline 2
(Date:1/22/2015)... 22, 2015 Increasing sophistication among enterprise buyers of ... purchasing in 2015, says Moravia CMO, ... study by market research firm Common Sense Advisory, 15 ... their translation and localization needs. "From a language industry ...
(Date:1/22/2015)... 2015 Research and Markets ( http://www.researchandmarkets.com/research/x3hp3g/microbiology ... "Microbiology Testing/Clinical Microbiology Market by Product, Clinical Application ... report to their offering. Clinical ... for the detection of infectious diseases. The respiratory ...
(Date:1/22/2015)... , Jan. 22, 2015 The Parenteral Drug Association ... Program SM : Enabling Pharmaceutical Manufacturing,s Future. ... the following goals: , Highlight the ongoing focus ... and build practical solutions by filling known gaps in current ...
Breaking Medicine Technology:Moravia Sees Single-Sourcing as Key Localization Trend in 2015 2Global Microbiology Testing/Clinical Microbiology (Instrument, Analyzer, Incubator, Kit, Microscope, Molecular Diagnostics) Market - Forecast to 2019 2Global Microbiology Testing/Clinical Microbiology (Instrument, Analyzer, Incubator, Kit, Microscope, Molecular Diagnostics) Market - Forecast to 2019 3PDA Launches Manufacturing Science Program(SM) 2PDA Launches Manufacturing Science Program(SM) 3
Sandhill Scientific offers a comprehensive selection of solid state and water perfused catheters for both adult & pediatric applications.Contact Sandhill Scientific for full details...
Each solid state catheter kit below is supplied with adapter cable(s) for Polygraf ID and a Manometric Calibrator....
Esophageal Stylet for LATITUDE® Air-Charged Catheter...
MMS Adapter Cable for LATITUDE® Air-Charged Catheter...
Medicine Products: