Navigation Links
Study to examine new treatment for West Nile virus
Date:8/18/2010

(CHICAGO) Neurological and infectious disease experts at Rush University Medical Center are testing a new drug therapy for the treatment of individuals with West Nile fever or suspected central nervous system infection due to the West Nile virus. Rush is the only site in the Midwest enrolling patients into the $50 million dollar, NIH-funded, Phase II clinical trial called PARADIGM.

The new drug treatment for West Nile virus that is being tested, also known as MGAWN1, is a humanized monoclonal antibody, which is a drug engineered to help the body seek and destroy the virus. During the randomized, double-blind study, patients with the signs and symptoms of West Nile virus will receive either a single infusion of MGAWN1 or a placebo.

"Currently, there are no approved treatments for people with severe West Nile virus infection and there is no standard of care that is highly effective against it," said Dr. Russell Bartt, neurologist and lead site investigator of the study at Rush. "Patients with the disease are hospitalized and receive supportive care."

"This new drug therapy has the potential of neutralizing the virus and could possibly reduce or prevent complications associated with the West Nile neuroinvasive disease," said Bartt. "This could represent a significant advancement for patients with West Nile."

The monoclonal antibody latches on to the West Nile virus in order for the body's immune system to recognize and eliminate it. The treatment will hopefully reduce the severity and also shorten the length of the disease.

The PARADIGM study will be testing the safety and tolerability of the drug therapy in infected patients. The first phase of the study of MGAWN1 tested doses in healthy adults and demonstrated adequate safety and was tolerated well.

West Nile virus is a disease transmitted through the bite of an infected mosquito. When someone is bitten by an infected mosquito, the virus can enter th
'/>"/>

Contact: Deb Song
deb_song@rush.edu
312-942-0588
Rush University Medical Center
Source:Eurekalert

Page: 1 2

Related medicine news :

1. When Doctors Admit Mistakes, Fewer Malpractice Suits Result, Study Says
2. MRSA policies differ among hospitals, study shows
3. Study examines risks, rewards of energy drinks
4. Berkeley study shows ozone and nicotine a bad combination for asthma
5. Henry Ford Hospital study: Donor Risk Index does not impact outcomes on a small scale
6. In NIH-funded study, researchers uncover step in brain events leading up to addiction
7. Lithium of No Benefit in ALS, Study Finds
8. Study shows behaviors and attitudes towards oral sex are changing
9. Study Offers Support for Surgery After Compression Fracture
10. More Medicaid Patients Using ERs, Study Finds
11. Study shows physicians reluctant to use chemoprevention for prostate cancer
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:11/28/2014)... 2014 BambooFlooringChina.com has been recognized as ... Recently, the business has announced its new strand ... big discount on these new models. , Based on ... hands, without carpenter machines involved. It is crafted on ... great for do-it-yourselfers without hard work on installation, also ...
(Date:11/28/2014)... November 28, 2014 Dr. Diane Walder, ... , announced the addition of Dr. Bridgit Nolan to ... the practice after having completed her dermatology residency at ... Dr. Walder invited Dr. Nolan to join ... surgery and cosmetic dermatology. Not only does Dr. Nolan ...
(Date:11/28/2014)... 2014 Dr. Andrew Campbell, one of ... the expansion of Quintessa Aesthetic Center into a third ... at W307 N1497 Golf Road in Suite 200 and ... Campbell, the new Delafield location will offer a variety ... including: Botox, filler injectables , micro laser peels, ...
(Date:11/28/2014)... Melbourne, Australia (PRWEB) November 28, 2014 ... has undergone healthy growth over the past five ... population's increasing acceptance of therapies that are either ... conventional treatments. According to IBISWorld industry analyst David ... the ageing population and growing private health insurance ...
(Date:11/28/2014)... Nov. 27, 2014 (HealthDay News) -- Planning on seconds ... chronic heartburn -- clinically known as gastroesophageal reflux disease (GERD) ... Dr. Jordan Josephson, an ear, nose and throat specialist at ... tips to help manage GERD on Thanksgiving: ... at least two small meals throughout the day. It,s also ...
Breaking Medicine News(10 mins):Health News:BambooFlooringChina.com Introduces Its New Strand Woven Bamboo Flooring Collection 2Health News:Dr. Diane Walder Welcomes New Cosmetic Dermatologist to Practice 2Health News:Dr. Andrew Campbell to Expand Quintessa Aesthetic Center into Delafield 2Health News:Alternative Health Therapies in Australia Industry Market Research Report Now Updated by IBISWorld 2Health News:Alternative Health Therapies in Australia Industry Market Research Report Now Updated by IBISWorld 3Health News:Alternative Health Therapies in Australia Industry Market Research Report Now Updated by IBISWorld 4Health News:Don't Let Chronic Heartburn Spoil Your Thanksgiving Feast 2
... , , PITTSBURGH, Sept. 14 ... is prototyping an innovative stroke treatment device designed to speed up ... , Michele Migliuolo, NeuroInterventions President and ... presentation at the 3 Rivers Venture Fair in Pittsburgh on Sept. ...
... NY, Sept. 13 /PRNewswire-FirstCall/ - (OTCBB: GVBP.OB) - GENova ... and develops novel drug targets that disrupt the advance ... Dr. Philip Gould as a Member Designate of its ... his career experience in multinational blue chip drug discovery ...
... ROCHESTER, Minn. -- Mayo Clinic researchers say that "teachable ... them diagnose cardiac infections without an invasive exam. Those ... on Antimicrobial Agents and Chemotherapy (ICAAC) in San Francisco. ... sometimes chambers of the heart -- can be a ...
... say they,ll donate than do, leaving long waits for transplants ... and large say they support the idea of donating some ... lives, reality presents a different picture. , Just 38 percent ... organ and tissue donors, according to a report this year ...
... , , DENVER, Sept. 11 ... kidney care services for those diagnosed with chronic kidney disease (CKD), kicks ... events raising funds and awareness of CKD across the nation -- on ... (Logo: http://www.newscom.com/cgi-bin/prnh/20020729/DAVITALOGO ) , , The ...
... ... PhD, JD, is Keynote Speaker on the Failed War on Drugs , ... Las Vegas, NV (PRWEB) September 11, 2009 -- ... Drug Policy Alliance advocating for drug reform in the United States as keynote speaker former ...
Cached Medicine News:Health News:Rapid-response Technology from NeuroInterventions, Inc. Aims to Quickly Restore Brain's Blood Flow After a Stroke 2Health News:GENova appoints Dr. Philip Gould to Scientific Advisory Board 2Health News:GENova appoints Dr. Philip Gould to Scientific Advisory Board 3Health News:Artificial intelligence helps diagnose cardiac infections 2Health News:For Organ Donation, Intent and Reality Don't Align 2Health News:For Organ Donation, Intent and Reality Don't Align 3Health News:DaVita Launches Nationwide Series of Kidney Awareness Run/Walks 2Health News:Healthcare Legal Issues Take the Stage at PAINWeek 2009 2Health News:Healthcare Legal Issues Take the Stage at PAINWeek 2009 3
(Date:11/28/2014)... Nov. 28, 2014  (Booth #7309, North Hall) — ... its newest product, DCMSYS Interface WebBridge, at the 100th ... at McCormick Place, Chicago, Illinois . ... Designed for medical facilities of any size, ... to upload any non-standard data (e.g. JPEG, TFF, PDF, ...
(Date:11/28/2014)... 2014 Chinese magnesium alloy maker DongGuan Eontec ... magnesium alloy bone fixation screw has received Chinese regulatory ... and instrument and that the company acknowledges receipt of ... Science and Technology Daily journalists Wang Xiangming ... and founder, Professor Li Yangde , has been ...
(Date:11/27/2014)... -- Javon Bea Mercy Health System President and ... Janesville Craig High School and Janesville Parker High School ... and Janesville Police and ... Janesville School District. The event was ... schools and other organizations with the resources needed to ...
Breaking Medicine Technology:Dicom Systems Announces WebBridge Interface at RSNA 2014 2Chinese magnesium alloy manufacturer Eontec expects to have its medical magnesium alloy available for clinical trial in 2015 2Chinese magnesium alloy manufacturer Eontec expects to have its medical magnesium alloy available for clinical trial in 2015 3Chinese magnesium alloy manufacturer Eontec expects to have its medical magnesium alloy available for clinical trial in 2015 4Mercy Health System, Janesville Police / Fire, provide casualty training to high school faculty 2Mercy Health System, Janesville Police / Fire, provide casualty training to high school faculty 3
... Medica,s ONCOLOGY and CancerNetwork today announced ... the clinical genetics service at Memorial Sloan-Kettering ... genetic testing in gastrointestinal cancers . ... colleagues bring clarity to when, why—and to what end—to refer ...
... Panasonic Healthcare Group today announced a new ... supplier for the hearing professional, which will allow ... at www.panasonic-hearingshop.com .  This is the first ... available for hearing care professionals to order online.    ...
Cached Medicine Technology:UBM Medica's ONCOLOGY to Feature Special Content on Role of Genetic Testing in GI Cancers 2Panasonic Reaches Distribution Agreement With The Hearing Shop 2Panasonic Reaches Distribution Agreement With The Hearing Shop 3Panasonic Reaches Distribution Agreement With The Hearing Shop 4
Markham-Meyerding Hemilaminectomy Retractors, self-retaining, Right....
Bookwalter Spinal Retractor...
The TEW Cranial/Spinal Retractor is designed for posterior fossa or intraspinal microsurgery where retraction is required....
... Infuse Bone Graft represents an rhBMP-2 (recombinant ... with a bovine-derived absorbable collagen sponge (ACS) ... fusion device is indicated for spinal fusion ... disc disease (DDD) at one level from ...
Medicine Products: