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Study ties bone marrow transplant to negative sexual side effects
Date:10/24/2013

their sexual health might not rebound as much or as quickly. Data have been limited to this point, prompting us to take a closer look at this issue in a larger, more diverse group of autologous and allogeneic transplant survivors over an extended period."

To further investigate long-term effects of SCT on the sexual health of survivors, a team of researchers led by senior author Smita Bhatia, MD, MPH, surveyed 277 adult patients (152 men and 125 women; median age 48) who underwent SCT at City of Hope for blood cancer between February 2001 and January 2005 about their sexual activity. Participants completed two questionnaires that together evaluated specific areas of sexual function (sexual cognition/fantasy, sexual arousal, sexual behavior/experience, orgasm, and drive/relationship) as well as sexual satisfaction at a median time of 17 days pre-transplant and at six, 12, 24, and 36 months post-transplant. A third questionnaire assessed overall health-related quality of life.

Investigators' analysis of questionnaire results (led by Dr. Wong) confirmed previous studies in demonstrating a definitive impact of SCT on survivors' post-transplant sexual activity. During the three-year post-transplant analysis period, the percentage of men who self-reported being "sexually active" (defined as having sex with a partner at least once in the preceding month) declined 7 percentage points, with 61 percent of men reporting sexual activity pre-transplant and 54 percent reporting activity post-transplant. The opposite a 15 percentage point increase in sexually active individuals was observed in women, with 37 percent reporting sexual activity pre-transplant and 52 percent reporting activity post-transplant.

In addition to further crystallizing transplantation's impact on survivors' sexual health, study data specifically associated diminished sexual function and satisfaction with transplant-related total body radiation in men and chronic GVHD with di
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Contact: Amanda Szabo
aszabo@hematology.org
202-552-4914
American Society of Hematology
Source:Eurekalert

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