Navigation Links
Study shows that surgical weight loss does not eliminate obstructive sleep apnea
Date:8/14/2008

Westchester, Ill. A study in the August 15 issue of the Journal of Clinical Sleep Medicine shows that surgical weight loss results in an improvement of obstructive sleep apnea (OSA), but most patients continue to have moderate to severe OSA one year after undergoing bariatric surgery. .Results of this study suggest that it is the severity of the condition, rather than a patient's presurgical weight, that determines if OSA will be resolved.

Results show that bariatric surgery reduced body mass index (BMI) from an average of 51 to 32 in 24 adults with OSA. At the one-year follow-up, however, only one participant (4 percent) experienced a resolution of OSA, and the majority of the study group (71 percent) still had moderate to severe OSA. Patients who have residual OSA after surgery are encouraged to maintain ongoing treatment with continuous positive airway pressure (CPAP) therapy.

The prevalence of OSA among obese individuals is high and correlates with increasing BMI; among the severely obese, the prevalence of OSA ranges from 55 percent to 90 percent. OSA itself may promote weight gain through ineffective sleep, impaired glucose metabolism and imbalances of leptin, ghrelin and orexin levels.

"We were surprised by the severity of the residual sleep apnea in postoperative patients," said principal investigator Christopher J. Lettieri, MD, Chief of Sleep Medicine at Walter Reed Army Medical Center. "The majority of individuals still had moderate to severe OSA."

"The second surprising finding of this study was that despite the persistence and severity of the disease, most people thought their sleep apnea was resolved after their weight loss and only a few still used CPAP," he said.

According to Lettieri, weight loss has many overall benefits; however, most people should not assume their OSA will be resolved after they have lost weight. The baseline apnea-hypopnea index (AHI), a measure used to identify the presence of OSA and define its severity, is the most important determinant of whether or not an individual will be cured of the disease. Individuals with a lower AHI may experience complete resolution of their OSA.

Twenty-four consecutive patients referred to the Pulmonary Critical Care and Sleep Medicine Service for preoperative evaluation of excessive daytime somnolence (EDS) prior to bariatric surgery were included in the study. Patients on average were 47.9 years, and most (75 percent) were women. Each was assessed by overnight polysomnography prior to and one year after undergoing bariatric surgery.

Postoperative polysomnography revealed reductions in the AHI in 22 subjects. Of the 12 patients whose AHI improved sufficiently to reclassify their OSA severity, three (12.5 percent) improved by more than one category of severity. Twenty-three patients had persistent OSA at follow-up. One patient had AHI less than five and no longer met the criteria for a diagnosis of OSA.

Although only seven patients (29 percent) subjectively complained of snoring postoperatively, all but one (96 percent) snored during the follow-up polysomnography. Significant improvements were noted on the Epworth Sleepiness Scale (EES); however, nearly half reported a persistence of daytime somnolence and more than half (54 percent) continued to have ESS scores greater than 10.

The authors of this study note that patients and physicians need to recognize that the subjective resolution of snoring after surgical weight loss does not equate to improvements or cure of OSA.


'/>"/>

Contact: Kelly Wagner
kwagner@aasmnet.org
708-492-0930
American Academy of Sleep Medicine
Source:Eurekalert

Related medicine news :

1. Study shows that older adult caregivers of people with dementia have worse sleep than noncaregivers
2. Study finds that sleep selectively preserves emotional memories
3. Study finds a wide variety of errors in testing process at family medicine clinics
4. Study finds not all hearing aids are created equal
5. Overweight Hispanic children at significant risk for pre-diabetes, according to new USC study
6. Public health clinic study links Americanization and depression
7. Case Western Reserve University study finds caregivers of spouses with dementia enjoy life less
8. Weight Loss After Diabetes Diagnosis Offers Big Benefits: Study
9. Losing Weight After Diabetes Diagnosis can Prevent Diabetes-Related Disease, Kaiser Permanente Study Finds
10. UNC study: Two-thirds of severe sports injuries to female students due to cheerleading
11. Athletes Study Shows Pride, Shame Universal Behaviors
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:1/20/2017)... Boca Raton, FL (PRWEB) , ... January 20, 2017 , ... ... supplement development, announced it attended the January ECRM trade show to continue the marketing ... technologically advanced vitamin C supplement, known for providing 400 percent better absorption than traditional ...
(Date:1/20/2017)... (PRWEB) , ... January 20, 2017 , ... ... wellness products to enhance people’s everyday lives, recently attended the January ECRM Trade ... , ATP Science is known for its large range of supplements that keep ...
(Date:1/20/2017)... (PRWEB) , ... January 20, 2017 , ... "TransFlare 4K ... use inside of Final Cut Pro X," said Christina Austin - CEO of Pixel ... RED Dragon. Utilizing the Dragon Sensor,TransFlare 4K Mystique lens flare and light leak transitions ...
(Date:1/20/2017)... , ... January 20, 2017 , ... “The Angel”: ... Lord has set out for each of his children. “The Angel” is the creation ... of Music in New York City, and impassioned writer. , When asked of her ...
(Date:1/20/2017)... ... 2017 , ... D R Burton Healthcare Products LLC, makers ... in a study indicating superior performance against competitive products in secretion clearance. ... Positive Expiratory Pressure Devices During Simulated Breathing“ was published in the winter issue ...
Breaking Medicine News(10 mins):
(Date:1/20/2017)... , January 20, 2017 Avillion LLP, ... appointment of Mark Weinberg , MD MBA as Chief Medical ... , USA . ... Dr Weinberg has spent more than 17 years ... 20" pharma companies to micro-cap biotech. Over the course of his ...
(Date:1/19/2017)... , Jan. 19, 2017 The U.S. Food ... of Chronic Idiopathic Constipation (CIC) in adult patients. ... chronic gastrointestinal disorders," said Julie Beitz , M.D., director ... Center for Drug Evaluation and Research. "With the availability of ... appropriate treatment for their condition." ...
(Date:1/19/2017)... 2017  Stealth BioTherapeutics Inc. ( Stealth ), a ... today announced new additions to its senior leadership team: ... Officer, and Daniel Geffken as interim Chief ... Carr , Pharm.D. has been promoted to Chief Clinical ... welcome Doug and Daniel to our management team, as ...
Breaking Medicine Technology: