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Study shows that surgical weight loss does not eliminate obstructive sleep apnea
Date:8/14/2008

Westchester, Ill. A study in the August 15 issue of the Journal of Clinical Sleep Medicine shows that surgical weight loss results in an improvement of obstructive sleep apnea (OSA), but most patients continue to have moderate to severe OSA one year after undergoing bariatric surgery. .Results of this study suggest that it is the severity of the condition, rather than a patient's presurgical weight, that determines if OSA will be resolved.

Results show that bariatric surgery reduced body mass index (BMI) from an average of 51 to 32 in 24 adults with OSA. At the one-year follow-up, however, only one participant (4 percent) experienced a resolution of OSA, and the majority of the study group (71 percent) still had moderate to severe OSA. Patients who have residual OSA after surgery are encouraged to maintain ongoing treatment with continuous positive airway pressure (CPAP) therapy.

The prevalence of OSA among obese individuals is high and correlates with increasing BMI; among the severely obese, the prevalence of OSA ranges from 55 percent to 90 percent. OSA itself may promote weight gain through ineffective sleep, impaired glucose metabolism and imbalances of leptin, ghrelin and orexin levels.

"We were surprised by the severity of the residual sleep apnea in postoperative patients," said principal investigator Christopher J. Lettieri, MD, Chief of Sleep Medicine at Walter Reed Army Medical Center. "The majority of individuals still had moderate to severe OSA."

"The second surprising finding of this study was that despite the persistence and severity of the disease, most people thought their sleep apnea was resolved after their weight loss and only a few still used CPAP," he said.

According to Lettieri, weight loss has many overall benefits; however, most people should not assume their OSA will be resolved after they have lost weight. The baseline apnea-hypopnea index (AHI), a measure used to identify the pre
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Contact: Kelly Wagner
kwagner@aasmnet.org
708-492-0930
American Academy of Sleep Medicine
Source:Eurekalert

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