Navigation Links
Study shows that surgical weight loss does not eliminate obstructive sleep apnea
Date:8/14/2008

Westchester, Ill. A study in the August 15 issue of the Journal of Clinical Sleep Medicine shows that surgical weight loss results in an improvement of obstructive sleep apnea (OSA), but most patients continue to have moderate to severe OSA one year after undergoing bariatric surgery. .Results of this study suggest that it is the severity of the condition, rather than a patient's presurgical weight, that determines if OSA will be resolved.

Results show that bariatric surgery reduced body mass index (BMI) from an average of 51 to 32 in 24 adults with OSA. At the one-year follow-up, however, only one participant (4 percent) experienced a resolution of OSA, and the majority of the study group (71 percent) still had moderate to severe OSA. Patients who have residual OSA after surgery are encouraged to maintain ongoing treatment with continuous positive airway pressure (CPAP) therapy.

The prevalence of OSA among obese individuals is high and correlates with increasing BMI; among the severely obese, the prevalence of OSA ranges from 55 percent to 90 percent. OSA itself may promote weight gain through ineffective sleep, impaired glucose metabolism and imbalances of leptin, ghrelin and orexin levels.

"We were surprised by the severity of the residual sleep apnea in postoperative patients," said principal investigator Christopher J. Lettieri, MD, Chief of Sleep Medicine at Walter Reed Army Medical Center. "The majority of individuals still had moderate to severe OSA."

"The second surprising finding of this study was that despite the persistence and severity of the disease, most people thought their sleep apnea was resolved after their weight loss and only a few still used CPAP," he said.

According to Lettieri, weight loss has many overall benefits; however, most people should not assume their OSA will be resolved after they have lost weight. The baseline apnea-hypopnea index (AHI), a measure used to identify the presence of OSA and define its severity, is the most important determinant of whether or not an individual will be cured of the disease. Individuals with a lower AHI may experience complete resolution of their OSA.

Twenty-four consecutive patients referred to the Pulmonary Critical Care and Sleep Medicine Service for preoperative evaluation of excessive daytime somnolence (EDS) prior to bariatric surgery were included in the study. Patients on average were 47.9 years, and most (75 percent) were women. Each was assessed by overnight polysomnography prior to and one year after undergoing bariatric surgery.

Postoperative polysomnography revealed reductions in the AHI in 22 subjects. Of the 12 patients whose AHI improved sufficiently to reclassify their OSA severity, three (12.5 percent) improved by more than one category of severity. Twenty-three patients had persistent OSA at follow-up. One patient had AHI less than five and no longer met the criteria for a diagnosis of OSA.

Although only seven patients (29 percent) subjectively complained of snoring postoperatively, all but one (96 percent) snored during the follow-up polysomnography. Significant improvements were noted on the Epworth Sleepiness Scale (EES); however, nearly half reported a persistence of daytime somnolence and more than half (54 percent) continued to have ESS scores greater than 10.

The authors of this study note that patients and physicians need to recognize that the subjective resolution of snoring after surgical weight loss does not equate to improvements or cure of OSA.


'/>"/>

Contact: Kelly Wagner
kwagner@aasmnet.org
708-492-0930
American Academy of Sleep Medicine
Source:Eurekalert

Related medicine news :

1. Study shows that older adult caregivers of people with dementia have worse sleep than noncaregivers
2. Study finds that sleep selectively preserves emotional memories
3. Study finds a wide variety of errors in testing process at family medicine clinics
4. Study finds not all hearing aids are created equal
5. Overweight Hispanic children at significant risk for pre-diabetes, according to new USC study
6. Public health clinic study links Americanization and depression
7. Case Western Reserve University study finds caregivers of spouses with dementia enjoy life less
8. Weight Loss After Diabetes Diagnosis Offers Big Benefits: Study
9. Losing Weight After Diabetes Diagnosis can Prevent Diabetes-Related Disease, Kaiser Permanente Study Finds
10. UNC study: Two-thirds of severe sports injuries to female students due to cheerleading
11. Athletes Study Shows Pride, Shame Universal Behaviors
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:3/24/2017)... ... , ... “Vintage and Harvest A Cultivation of Christian Love” is the creation ... North Carolina with his wife, Anna Marie. He and his wife are the proud ... also the author of “Shadow and Substance.” , “Love, the agape kind, is seen ...
(Date:3/23/2017)... ... 2017 , ... In 2016 the World Health Organization declared the Zika virus ... Zika-related cases in the Americas within the next year. Lyme disease is one of ... skyrocketing to an estimated 329,000. Yet, Zika, Lyme and other insect borne illnesses are ...
(Date:3/23/2017)... ... March 23, 2017 , ... Demonstrating ... communities, 16 more public health departments have been awarded national accreditation through the ... million people into the expanding network of communities across the nation whose health ...
(Date:3/23/2017)... ... March 23, 2017 , ... The IoT (Internet of Things) is ... making a huge impact on businesses and individual consumers alike. Laboratories can maximize ... have a value anywhere from $4 trillion to $11 trillion dollars by the year ...
(Date:3/23/2017)... , ... March 23, 2017 ... ... financial services firm serving the families and businesses of the Norwalk and ... program. Northern Ohio Recovery Center (N.O.R.A.) is a nonprofit, community-based substance abuse ...
Breaking Medicine News(10 mins):
(Date:3/24/2017)... March 24, 2017 ShangPharma, a ... and cost-effective drug development and discovery services, ... biotechnology industry, announced today the intent for ... will be consolidating the Contract Research Organizations ... Shanghai ChemPartner. These entities include ChemPartner Shanghai, ...
(Date:3/24/2017)... India , March 24, 2017 A ... market has been growing rapidly as the global sales of Adcetris ... the growth in the antibody drug conjugates market is driven by ... of cancer and wider therapeutic window offered by ADCs. ... Browse 3 Tables and 94 ...
(Date:3/24/2017)... , March 24, 2017  Eli Lilly and ... plans to invest $850 million in its U.S. ... across its U.S. enterprise, including research laboratories, manufacturing ... are being driven by demand for Lilly products, ... medicines in development targeting cancer, pain, diabetes and ...
Breaking Medicine Technology: