Navigation Links
Study shows that maintenance rituximab is useful for advanced indolent lymphoma
Date:3/10/2009

ar progression-free survival was also higher in the MR group: 68% vs. 33% in controls. In the sub group of 282 patients with follicular lymphoma, the corresponding rates were 64% and 33%. With more than ten years follow-up, the patients receiving MR went nearly 5 years on average before relapse, compared with 1.9 years without .

According to the National Cancer Institute, lymphoma is a disease in which malignant cancer cells form in the lymph system. Indolent lymphoma includes several sub-types of lymphoma that tend to grow and spread slowly, and has few symptoms. It's also called low-grade lymphoma.

The anti-CD20 monoclonal antibody, rituximab was approved for use in follicular lymphoma and indolent lymphoma in 1997 for those no longer responding to chemotherapy. In this setting, the objective response rate was 48% and the agent had rare serious adverse effects, generally limited to infusional toxicity. On the basis of earlier trials, the E1496 study, is the first to test rituximab to maintain response to chemotherapy in indolent lymphoma. Observations from this most recent study add to a substantial body of evidence that the combination of rituximab with chemotherapy is a new standard for patients with indolent lymphoma who require treatment.

The National Cancer Institute funded this multi-center, national trial through ECOG, which began in 1997. Trial centers included the NYU Langone Medical Center in New York City, the Dana Farber Cancer Institute in Boston, Columbia Cancer Agency in Vancouver, the Mayo Clinic in Rochester, Northwestern University in Chicago, Stanford University in Stanford and the University of Maryland in Baltimore.

"This study has led to a new FDA indication for the use of rituximab as maintenance therapy in patients with indolent lymphoma," states Dr. Hochster.


'/>"/>

Contact: Dorie Klissas
dorie.klissas@nyumc.org
212-404-3555
NYU Langone Medical Center / New York University School of Medicine
Source:Eurekalert

Page: 1 2

Related medicine news :

1. Study Links Blood Type and Pancreatic Cancer
2. New study identifies risk factors in severity of flat head syndrome in babies
3. New Study Shows That One-Third of Shelter Youth Have Been Institutionalized; Almost One-Half Suffered Violence in the Home
4. Beaumont Launches 1st U.S. Adult Human Stem Cell Study for Stress Urinary Incontinence
5. Common Approaches to Member Retention by Health Insurance Plans are Ineffective, New Study Shows
6. Celator(R) Pharmaceuticals Enrolls First Patient in Its Phase 2 Study of CPX-351 in Acute Myeloid Leukemia in First Relapse
7. Study Shows 80% of Adults with Peripheral Arterial Disease Go Undiagnosed
8. Study finds pay for performance stimulates changes in medical practice
9. Study: Doctor-patient conversations at end of life associated with lower medical expenses
10. Study tests reliability of more accurate measure of patient pain
11. New published study demonstrates over-the-counter device lowers blood pressure in diabetic patients
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:10/20/2014)... Pittsburgh, PA (PRWEB) October 20, 2014 ... new, minimally-invasive procedure that enables physicians to repair a ... , The MitraClip system, developed by ... regurgitation (MR), a progressive and life-threatening condition in which ... allowing blood to flow backward from the heart’s left ...
(Date:10/20/2014)... hc1.com today announced the launch of ... enables healthcare organizations of all sizes to immediately ... management (“CRM”) solution. , Designed from the ground ... healthcare industry, the hc1 Healthcare Relationship Cloud™ personalizes ... combining healthcare CRM, HIPAA-compliant collaboration, and real-time analytics ...
(Date:10/20/2014)... October 20, 2014 AttorneyOne.com, a recognized authority ... information from the FDA on Sit and Slim II ... not to purchase or use Sit and Slim II because ... II is promoted as weight loss product on various websites ... the market in 2010 for safety reasons, can significantly increase ...
(Date:10/20/2014)... (PRWEB) October 20, 2014 National Teen Driver ... of the American Academy of Pediatrics (Ohio AAP, http://www.ohioaap.org ... in encouraging parents of teen drivers to talk to their ... road. , Motor vehicle crashes are the leading cause of ... drivers involved in fatal crashes, and 859 (42%) of those ...
(Date:10/20/2014)... Houston plastic surgeon Dr. Christopher ... of his innovative True Form Tummy Tuck® ... and faculty at The University of Texas Medical ... once a medical student. Patronella, who is a founding ... surgery practices in Texas, The Aesthetic Center for ...
Breaking Medicine News(10 mins):Health News:Allegheny General Hospital Introduces New, Beating-Heart Procedure for Mitral Valve Repair 2Health News:Allegheny General Hospital Introduces New, Beating-Heart Procedure for Mitral Valve Repair 3Health News:Healthcare Relationship Management (HRM) Leader hc1.com® Launches hc1® Quick Start™ 2Health News:FDA Advises Not to Use Sit and Slim II: AttorneyOne Monitors and Keeps Consumers Informed 2Health News:Ohio AAP Promotes National Teen Driver Safety Week 2Health News:Plastic Surgeon Patronella Presents Artistically-Inspired Tummy Tuck Method to Future Generation of Plastic Surgeons in Texas 2
... cardiovascular diseases.,A potbelly indicates that the risk of a heart ... is skinny as a beanpole. ,This new study ... of waist size to the hips, an elevated waist-to-hip ratio ... that even people who would otherwise be considered safe going ...
... Women who exercise by doing household chores like dusting, ... cancer, suggests a new study.// ,The research ... from nine European countries and found that doing housework ... the online edition of BBC News. , ,It ...
... acquired but quite difficult to stop.// All habitual smokers who ... have to try out recommended smoking cessation methods. ... 16 and 24 years do try to quit smoking but ... methods. ,An article presented in Morbidity and Mortality ...
... undergo a double hand transplant was ecstatic as she got ... "I'm doing very well, I'm very happy. I'm taking steps ... life. When I saw the hands after the operation, they ... her arms following an explosion in a laboratory in 1978, ...
... that a flabby waist certainly points to a greater risk of ... study has revealed that the risk for coronary illness is inflated ... sports a podgy flabby waistline. ,The diameter along the median ... amounts to an imaginary line cutting through the body joining two ...
... government of Bharatiya Janta Party has been inspired from ... devise a family planning programme for the Muslim community// ... religious texts and clerics for awareness campaign as well ... comes in the way of family planning is ignorance ...
Cached Medicine News:Health News:Pot Belly Is A Better Risk Predictor Of Heart Attack Than BMI 2Health News:Tried To Quit Smoking And Failed? Call 1-800-QUIT-NOW 2Health News:Madhya Pradesh Imbibes Family Planning Lessons from Pakistan 2
(Date:10/17/2014)... 2014 According to ... Technique (Optical Coherence Tomography, Hyperspectral Imaging, Photoacoustic ... Neurology, Oncology, Cardiology) - Global Forecasts to ... Optical Imaging market over the forecast period ... $917.1 million in 2014 and is expected ...
(Date:10/17/2014)... 2014 The following is being released ... The Green Park Collaborative (GPC) will bring ... payers, medical device and pharmaceutical companies, as well ... 12, 2015 at its first ever workshop on ... treatments.  Participants will discuss study designs to evaluate ...
(Date:10/17/2014)... BALTIMORE , Oct. 17, 2014  Ameritox SM ... announced the appointment of Thomas Smith , M.D., ... lead a field-based team offering scientific resources for healthcare ... Smith has held leadership positions at a variety of ... will benefit both the pain and behavioral health sides ...
Breaking Medicine Technology:Optical Imaging Market Worth $1,669.2 Million by 2019 2Optical Imaging Market Worth $1,669.2 Million by 2019 3Optical Imaging Market Worth $1,669.2 Million by 2019 4Green Park Collaborative to Discuss Comparative Effectiveness and Value of Weight Loss Treatments 2Ameritox Appoints New Chief Medical Officer 2
... ... ... ... ...
... , ... ... ... ...
Cached Medicine Technology:BNA Books' Announces Publication of New 2009 Cumulative Supplement to 'Pharmaceutical Law: Regulation of Research, Development, and Marketing' 2BNA Books' Announces Publication of New 2009 Cumulative Supplement to 'Pharmaceutical Law: Regulation of Research, Development, and Marketing' 3BNA Books' Announces Publication of New 2009 Cumulative Supplement to 'Pharmaceutical Law: Regulation of Research, Development, and Marketing' 4BNA Books' Announces Publication of New 2009 Cumulative Supplement to 'Pharmaceutical Law: Regulation of Research, Development, and Marketing' 5BNA Books' Announces Publication of New 2009 Cumulative Supplement to 'Pharmaceutical Law: Regulation of Research, Development, and Marketing' 6BNA Books' Announces Publication of New 2009 Cumulative Supplement to 'Pharmaceutical Law: Regulation of Research, Development, and Marketing' 7BNA Books' Announces Publication of New 2009 Cumulative Supplement to 'Pharmaceutical Law: Regulation of Research, Development, and Marketing' 8BNA Books' Announces Publication of New 2009 Cumulative Supplement to 'Pharmaceutical Law: Regulation of Research, Development, and Marketing' 9China Biologic Products to Present at the Rodman & Renshaw Annual China Investment Conference 2China Biologic Products to Present at the Rodman & Renshaw Annual China Investment Conference 3China Biologic Products to Present at the Rodman & Renshaw Annual China Investment Conference 4China Biologic Products to Present at the Rodman & Renshaw Annual China Investment Conference 5China Biologic Products to Present at the Rodman & Renshaw Annual China Investment Conference 6China Biologic Products to Present at the Rodman & Renshaw Annual China Investment Conference 7China Biologic Products to Present at the Rodman & Renshaw Annual China Investment Conference 8
... The assay is an immunometric ... measurement of Prolactin in human ... the sample is bound by ... different epitopes. One antibody is ...
... hormone secreted in significant amounts by the ... in synergy with estrogen, plays an important ... of mammary gland growth and lactation in ... effects on cell growth in other tissues ...
... The AxSYM BNP assay allows ... in the status of your heart ... BNP versus NT-ProBNP. The AxSYM BNP ... fast, simple, walk-away resultson a platform ...
... this Enzyme ImmunoAssay (EIA) is as follows: ... on a 96 well microtiter plate. After ... the trapped molecule is covalently linked to ... After washing and denaturing treatment, Angiotensin II ...
Medicine Products: