Navigation Links
Study shows that maintenance rituximab is useful for advanced indolent lymphoma
Date:3/10/2009

ar progression-free survival was also higher in the MR group: 68% vs. 33% in controls. In the sub group of 282 patients with follicular lymphoma, the corresponding rates were 64% and 33%. With more than ten years follow-up, the patients receiving MR went nearly 5 years on average before relapse, compared with 1.9 years without .

According to the National Cancer Institute, lymphoma is a disease in which malignant cancer cells form in the lymph system. Indolent lymphoma includes several sub-types of lymphoma that tend to grow and spread slowly, and has few symptoms. It's also called low-grade lymphoma.

The anti-CD20 monoclonal antibody, rituximab was approved for use in follicular lymphoma and indolent lymphoma in 1997 for those no longer responding to chemotherapy. In this setting, the objective response rate was 48% and the agent had rare serious adverse effects, generally limited to infusional toxicity. On the basis of earlier trials, the E1496 study, is the first to test rituximab to maintain response to chemotherapy in indolent lymphoma. Observations from this most recent study add to a substantial body of evidence that the combination of rituximab with chemotherapy is a new standard for patients with indolent lymphoma who require treatment.

The National Cancer Institute funded this multi-center, national trial through ECOG, which began in 1997. Trial centers included the NYU Langone Medical Center in New York City, the Dana Farber Cancer Institute in Boston, Columbia Cancer Agency in Vancouver, the Mayo Clinic in Rochester, Northwestern University in Chicago, Stanford University in Stanford and the University of Maryland in Baltimore.

"This study has led to a new FDA indication for the use of rituximab as maintenance therapy in patients with indolent lymphoma," states Dr. Hochster.


'/>"/>

Contact: Dorie Klissas
dorie.klissas@nyumc.org
212-404-3555
NYU Langone Medical Center / New York University School of Medicine
Source:Eurekalert

Page: 1 2

Related medicine news :

1. Study Links Blood Type and Pancreatic Cancer
2. New study identifies risk factors in severity of flat head syndrome in babies
3. New Study Shows That One-Third of Shelter Youth Have Been Institutionalized; Almost One-Half Suffered Violence in the Home
4. Beaumont Launches 1st U.S. Adult Human Stem Cell Study for Stress Urinary Incontinence
5. Common Approaches to Member Retention by Health Insurance Plans are Ineffective, New Study Shows
6. Celator(R) Pharmaceuticals Enrolls First Patient in Its Phase 2 Study of CPX-351 in Acute Myeloid Leukemia in First Relapse
7. Study Shows 80% of Adults with Peripheral Arterial Disease Go Undiagnosed
8. Study finds pay for performance stimulates changes in medical practice
9. Study: Doctor-patient conversations at end of life associated with lower medical expenses
10. Study tests reliability of more accurate measure of patient pain
11. New published study demonstrates over-the-counter device lowers blood pressure in diabetic patients
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:12/26/2014)... 26, 2014 India Network Foundation, a ... the USA, announced today a new version of “ ... choosing the right plan for their visiting parents. The ... of the selection process when choosing an insurance plan ... with only a few clicks. Many elderly Asian Indian ...
(Date:12/26/2014)... December 26, 2014 Parker & ... the best in heating, cooling and plumbing contractor ... hour emergency services in 2014 with regard to ... that Arizona is known for its incredibly hot ... understands the intricacies and details of a wide ...
(Date:12/25/2014)... The click strand woven ... and durability. Today, the business announces a click ... until Jan. 30, 2015. , Click strand woven ... BambooFlooringChina.com is a well-known brand in the bamboo ... find a reliable bamboo flooring supplier. , “We ...
(Date:12/25/2014)... 25, 2014 Product liability lawsuits filed ... recall ( http://www.consumerinjurylawyers.com/DePuy/ ) continue to move forward in ... Order issued in the U.S. District Court, Northern District ... an open conference on January 7, 2015, at the ... in West Palm Beach, Florida. The Conference is scheduled ...
(Date:12/25/2014)... Dylan Queen, a famous online company supplying women’s special ... prom dresses, most of which are priced under $200. ... the promotion is valid until Jan. 22, 2015; the ... market. , The prom dresses in this new collection ... strapless, empire strapless chiffon, one shoulder, floor-length, V-neck beading, ...
Breaking Medicine News(10 mins):Health News:India Network Health Insurance Announces new Comprehensive Pre-existing Condition Coverage policy for Visitors to the United States 2Health News:India Network Health Insurance Announces new Comprehensive Pre-existing Condition Coverage policy for Visitors to the United States 3Health News:Parker & Sons Announces Record Demand For 24 Hour Emergency Services In 2014 With Regard To Air-Conditioning Systems 2Health News:Parker & Sons Announces Record Demand For 24 Hour Emergency Services In 2014 With Regard To Air-Conditioning Systems 3Health News:BambooFlooringChina.com: click strand woven bamboo flooring promotion valid until Jan. 30, 2015. 2Health News:Federal Court Overseeing DePuy ASR Hip Lawsuit Set to Convene Conference in January, Bernstein Liebhard LLP Reports 2Health News:Federal Court Overseeing DePuy ASR Hip Lawsuit Set to Convene Conference in January, Bernstein Liebhard LLP Reports 3Health News:Dylan Queen: Cheap Prom Dresses for the UK Market 2
... Georgia State University and the Georgia Institute of Technology ... around Atlanta with a dedicated magnetic resonance imaging scanner ... and mind. , The Center for Advanced Brain Imaging, ... opened this month for researchers exploring topics from autism ...
... Global eHealth solutions provider ICW celebrates its opening in ... Newt Gingrich, Founder of the Center for Health ... with Frank McKenna, Deputy Chair of TD Bank Financial ... CEO of eHealth specialist InterComponentWare AG (ICW), will celebrate ...
... Imaginis.com today announced that it has again received the ... the Health Information Resource Center. Imaginis received a merit ... for the period of Spring/Summer 2008. This is ... Health Award. The WWW Health Awards program recognizes the ...
... and personal skillsWASHINGTON, March 18 A new survey ... with support from The Atlantic Philanthropies and the California ... care system for millions of Americans suffering from a ... Re-Forming Health Care: Americans Speak Out about Chronic Conditions ...
... received a pledge of $10.5 million to create ... professorship and an international scholars training program, from ... wishes to remain anonymous. This pledge represents the ... Medicine. , "This exceedingly generous commitment is an ...
... in partnership with Children,s Hospital of Michigan will teach ... travelProper use of booster seats and car restraints is ... DETROIT, March 18 Parents and caregivers can learn ... vehicle travel during the Second Annual Child Car ...
Cached Medicine News:Health News:Georgia State/Georgia Tech Center for Advanced Brain Imaging to expand brain, mind research 2Health News:Gingrich and McKenna to Speak on Transformation of Healthcare Delivery at ICW Launch 2Health News:Video: NCOA Issues Call-to-Action for National Chronic Care Reform Based on Results of Comprehensive Survey of Americans with Chronic Conditions 2Health News:Video: NCOA Issues Call-to-Action for National Chronic Care Reform Based on Results of Comprehensive Survey of Americans with Chronic Conditions 3Health News:Video: NCOA Issues Call-to-Action for National Chronic Care Reform Based on Results of Comprehensive Survey of Americans with Chronic Conditions 4Health News:BU School of Medicine receives $10.5 million pledge 2Health News:Wayne County Community College District Presents Second Annual Child Car Seat Check Program 2
(Date:12/24/2014)... 2014  Conkwest, Inc., the Natural Killer Cell ... Killer (NK) cell-line platform, Neukoplast® (NK-92™) as an ... , NantWorks founder, physician scientist and biotechnology entrepreneur, ... approximately $48 million of the Company,s Class A ... will be named Co-Chairman of the Conkwest Board ...
(Date:12/24/2014)... and LONDON , December ... orthopedic industry are expected to grow at an average ... terms of value and volume. Hip, knee and spine ... world while in emerging economies they have a lower ... are challenging the use of composites. Non-metallic orthopedic devices ...
(Date:12/24/2014)... , Dec. 23, 2014  Advanced Medical Isotope ... engaged primarily in the development of brachytherapy devices ... today announced that it has filed a ... Drug Administration ("FDA") for marketing clearance for its ... of the U.S. Food, Drug and Cosmetic Act ...
Breaking Medicine Technology:Conkwest Announces $50m In Strategic Investments And Appoints NantWorks Founder, Dr. Patrick Soon-Shiong As Co-Chairman Of The Board 2Conkwest Announces $50m In Strategic Investments And Appoints NantWorks Founder, Dr. Patrick Soon-Shiong As Co-Chairman Of The Board 3Conkwest Announces $50m In Strategic Investments And Appoints NantWorks Founder, Dr. Patrick Soon-Shiong As Co-Chairman Of The Board 4Conkwest Announces $50m In Strategic Investments And Appoints NantWorks Founder, Dr. Patrick Soon-Shiong As Co-Chairman Of The Board 5Use of Composites in Orthopedic Industry to Reach $596 Million by 2020 2Use of Composites in Orthopedic Industry to Reach $596 Million by 2020 3Advanced Medical Isotope Corporation Files a "de novo" Submission for Y-90 RadioGel(TM) Device 2Advanced Medical Isotope Corporation Files a "de novo" Submission for Y-90 RadioGel(TM) Device 3
... 2007- Biota Holdings,Limited (ASX:BTA) today announced that ... anti-influenza,treatment, has: , ,1. demonstrated effectiveness against ... I studies in Japan; and ,3. received ... the,UK. , ,Biota’s partner for LANI, Daiichi-Sankyo, ...
... GENEVA, April 20, 2007 /PRNewswire/ -- Addex Pharmaceuticals,announced ... proof of,concept trial with its lead compound ADX10059 ... objective, the absence of,pain at 2 hours after ... improvement in pain-free status and,improvement of migraine pain ...
Cached Medicine Technology:LANI completes Phase I in Japan and to commence Phase I in UK 2LANI completes Phase I in Japan and to commence Phase I in UK 3LANI completes Phase I in Japan and to commence Phase I in UK 4Addex Reports Positive Results in Phase IIa Clinical Trial With,ADX10059 in Migraine 2Addex Reports Positive Results in Phase IIa Clinical Trial With,ADX10059 in Migraine 3Addex Reports Positive Results in Phase IIa Clinical Trial With,ADX10059 in Migraine 4
... is a fully automated ... for clotting, photometric and ... tests.The medium-throughput analyser offers ... tubes, 45 reagents onboard, ...
... KeraCel Ophthalmic Products are constructed ... of lint-free MEROCEL polyvinyl acetal ... to be beneficial to both ... absorbent, and yet firm enough ...
... Haemolance safety lancets are ... to obtain capillary blood ... frequently used for monitoring ... may also be used ...
The Unistik 3 family of single use safety lancets has 4 models for use across all clinical environments....
Medicine Products: