Navigation Links
Study shows that maintenance rituximab is useful for advanced indolent lymphoma
Date:3/10/2009

A new study has found for the first time that maintenance therapy with the novel antibody, rituximab (MR) following cyclophosphamide, vincristine and prednisone (CVP) therapy improves progression-free survival in patients with stage III-IV indolent lymphoma, according to Howard S. Hochster, M.D. of NYU Langone Medical Center, lead author of a recent study published online ahead of print in the Journal of Clinical Oncology.

In a study, sponsored by the National Institutes of Health and conducted by the Eastern Cooperative Oncology Group (ECOG) titled, "Maintenance Rituximab After Cyclophosphamide, Vincristine, and Prednisone Prolongs Progression-Free Survival in Advanced Indolent Lymphoma: Results of the Randomized Phase III ECOG1496 Study," researchers looked at 311 patients with stable or responding disease after CVP therapy. The patients were randomly assigned to observation only or a maintenance rituximab (MR) 375 mg/square meter once per week for 4 weeks every 6 months for 2 years. Results are the first phase III data showing patients with untreated indolent lymphoma can be given (MR) after chemotherapy with minimal toxicity to prevent relapse.

"Low grade lymphoma is very treatable, with patients living many years on the average," says Howard Hochster, M.D. professor of medicine and clinical pharmacology at NYU School of Medicine and director of gastrointestinal oncology and early drug development at the NYU Cancer Institute. "But no one treatment to date has been able to show benefit on long term survival. This reasonably non-toxic antibody can improve disease free survival by several years and possibly effect overall survival. In this group of patients, even 10 years of observation is a little too soon to show survival benefits, but the trend is present."

An improved disease response was seen in 22% of rituximab-treated patients versus just 7% of control subjects. Toxic effects were minimal in both groups. Three ye
'/>"/>

Contact: Dorie Klissas
dorie.klissas@nyumc.org
212-404-3555
NYU Langone Medical Center / New York University School of Medicine
Source:Eurekalert

Page: 1 2

Related medicine news :

1. Study Links Blood Type and Pancreatic Cancer
2. New study identifies risk factors in severity of flat head syndrome in babies
3. New Study Shows That One-Third of Shelter Youth Have Been Institutionalized; Almost One-Half Suffered Violence in the Home
4. Beaumont Launches 1st U.S. Adult Human Stem Cell Study for Stress Urinary Incontinence
5. Common Approaches to Member Retention by Health Insurance Plans are Ineffective, New Study Shows
6. Celator(R) Pharmaceuticals Enrolls First Patient in Its Phase 2 Study of CPX-351 in Acute Myeloid Leukemia in First Relapse
7. Study Shows 80% of Adults with Peripheral Arterial Disease Go Undiagnosed
8. Study finds pay for performance stimulates changes in medical practice
9. Study: Doctor-patient conversations at end of life associated with lower medical expenses
10. Study tests reliability of more accurate measure of patient pain
11. New published study demonstrates over-the-counter device lowers blood pressure in diabetic patients
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:1/23/2015)... (PRWEB) January 23, 2015 Hastings and Hastings, ... matters, reports a record number of legal representation client review ... there has been a steady rise in the number of ... and at home throughout the Valley. With that said, a ... be reviewed by an experienced law firm. Hastings and Hastings ...
(Date:1/22/2015)... with its top dressmaking technologies, has been a leading dress ... its latest designs of wedding dresses and launching a site-wide ... all the fresh new products are designed for 2015, and ... off. All the clothes from LunaDress follow up with the ...
(Date:1/22/2015)... Padre Murphy's and Owner Tom Boyle in Glendale, AZ ... Alliance (PPHA). The PPHA's passion for others' well-being and ... greats, treated for obstructive sleep apnea (OSA) has propelled them ... in the valley. The most recent plans for an event ...
(Date:1/22/2015)... 2015 Blue Cross and Blue Shield of ... what it means to “Live Fearless.” , The ... share their stories about how they or someone they know ... by living in the moment. By telling these types of ...
(Date:1/22/2015)... 2015 A new white paper by ... person-centeredness in the long-term care environment as well as ... continuum. The paper, “The Power of Person-Centeredness in Long-Term ... practices of the patient, resident and family experience in ...
Breaking Medicine News(10 mins):Health News:Hastings and Hastings Reports a Record Number of Client Review Requests for Slip and Fall Accidents in 2014 2Health News:LunaDress Shows The Latest Styles Of Wedding Dresses In 2015 2Health News:Padre Murphy's Holds NFL Retired Players Association Party Star Studded Event With Bud Light and Pro Player Health Alliance Sponsoring 2Health News:Padre Murphy's Holds NFL Retired Players Association Party Star Studded Event With Bud Light and Pro Player Health Alliance Sponsoring 3Health News:Blue Cross and Blue Shield of Minnesota to Showcase “Faces of Fearless” 2Health News:The Power of Person-Centeredness in Long-Term Care Explored by The Beryl Institute 2Health News:The Power of Person-Centeredness in Long-Term Care Explored by The Beryl Institute 3
... 2009 -- Children regularly exposed to tobacco smoke at ... adulthood. This finding by researchers at Columbia University,s Mailman ... not recover completely from the effects of early-life exposures ... the December 2009 American Journal of Epidemiology . ...
... ... one percent of the risk of electronic cigarettes and that attacks on them are due ... ... Professor Carl Phillips, associate professor at the University of Alberta, has argued that electronic cigarettes ...
... ... American children overweight and obese, Smart for Life,s new THIN ADVENTURE(TM) ... for children between the ages of 6 and 14. It will be ... , The program was designed by Dr. Sasson Moulavi ( Dr. Sass ...
... , , Site recognized as Best Online Health ... , WESTPORT, Conn. , Dec. 28 dLife, the ... to its Web site dlife.com reached an all time high with ... in which dlife.com metrics rose 35%+ versus 2008 in visits and ...
... effectiveness, but many don,t, study finds , MONDAY, Dec. 28 ... don,t return for follow-up tests that make sure the procedure ... go back, and therefore risk an unwanted pregnancy, are more ... of four or more children, the study found. , The ...
... ... Hailed by best selling authors such as Jack Canfield, Dr. Joe ... after fitness guru to date, who entertains, educates and enlightens audiences worldwide ... Nicole Lee (JNL) is a weight loss success story who has become ...
Cached Medicine News:Health News:Exposure to tobacco smoke in childhood home associated with early emphysema in adulthood 2Health News:Professor: No Doubt Electronic Cigarettes Safer than Cigarettes 2Health News:THIN ADVENTURE(TM) Presents the First Children's Do-It-Yourself Weight-Loss Program 2Health News:THIN ADVENTURE(TM) Presents the First Children's Do-It-Yourself Weight-Loss Program 3Health News:THIN ADVENTURE(TM) Presents the First Children's Do-It-Yourself Weight-Loss Program 4Health News:dLife.com Hits 1 Million Plus Visitors! 2Health News:Half of Men Fail to Check if Vasectomy is Working 2Health News:Fitness Celebrity Jennifer Nicole Lee Reveals her Revolutionary Weight Loss Principles in 'The Mind, Body, and Soul Diet' Book 2Health News:Fitness Celebrity Jennifer Nicole Lee Reveals her Revolutionary Weight Loss Principles in 'The Mind, Body, and Soul Diet' Book 3Health News:Fitness Celebrity Jennifer Nicole Lee Reveals her Revolutionary Weight Loss Principles in 'The Mind, Body, and Soul Diet' Book 4
(Date:1/23/2015)... Pa. , Jan. 23, 2015  MedScope ( www.medscope.org ... been nominated for a 2015 Connected World ... Emergency Response System (mPERS), that can be used anywhere, ... technology partner.  In nominating MedScope, ...
(Date:1/23/2015)... Fla. and DUBLIN , Jan. ... the agreement with KRS Global Biotechnology, Inc. for the compounding, ... be compounded for shipment in the United States ... FDA approved Outsourcing Facility capable of compounding naltrexone tablets in ...
(Date:1/23/2015)... , Jan. 23, 2015  Pete Rose, baseball,s all-time hits leader, ... arthritis pain reliever Myoflex, Ducere Pharma has announced. ... are excited to have him on board with Myoflex," said ... is a legendary player who is known across all generations. ...
Breaking Medicine Technology:MedScope Nominated by RacoWireless for Prestigious 2015 Connected World Magazine Connected World Award 2Immune Therapeutics, Inc. Announces Agreement with KRS Global Biotechnology, Inc. 2Immune Therapeutics, Inc. Announces Agreement with KRS Global Biotechnology, Inc. 3Immune Therapeutics, Inc. Announces Agreement with KRS Global Biotechnology, Inc. 4Pete Rose bets on Myoflex to relieve aches and pains 2
...
Inquire...
Diamond Reusable Probed work with all ACMI™ instrument inserts. Dual trumpet valves provide smooth, effective fingertip control over suction and irrigation....
Corson Suction-Irrigation Probes are designed to provide flexibility and reliability in a disposable probe....
Medicine Products: