Navigation Links
Study shows that administering calcium and magnesium effectively reduces neurological sensitivity
Date:5/16/2008

ous placebo. Study results showed that the use of calcium and magnesium infusions before and after oxaliplatin was associated with a significant decrease in the incidence and severity of neurotoxicity, and it also delayed the time to the onset of neurotoxicity on oxaliplatin therapy.

Calcium and magnesium are an easily administered, safe treatment option for oxaliplatin-induced neurotoxicity. Some initial reports from other studies claimed that the use of calcium and magnesium reduced the activity of oxaliplatin-based chemotherapy, says Axel Grothey, M.D., an oncologist at Mayo Clinic and study co-chair. However, we have definitive results from an independent, blinded radiologic review which demonstrates no negative influence of calcium and magnesium on the outcome for oxaliplatin-based chemotherapy.

Now that we have shown the effectiveness of calcium and magnesium in reducing oxaliplatin-induced neurotoxicity, a further step may be to evaluate the benefit of calcium and magnesium in reducing neurotoxicity caused by other medications, says Dr. Nikcevich. Many other commonly used chemotherapy agents cause neurological sensitivity. By applying our study design, we can test the effectiveness of calcium and magnesium when used with other treatments.

This study was done as part of a program coordinated by Charles Loprinzi, M.D., a medical oncologist at Mayo Clinic Rochester. The program he leads has conducted more than 50 clinical trials designed to find ways to prevent or treat untoward symptoms related to cancer and cancer therapy. This includes three trials to evaluate ways to treat established neuropathy caused by chemotherapy and three additional studies to try to prevent such toxicity. Additional trials are in development to find other ways to alleviate this toxicity.


'/>"/>

Contact: Traci Klein
newsbureau@mayo.edu
507-284-5005
Mayo Clinic
Source:Eurekalert

Page: 1 2

Related medicine news :

1. ASCO Study Confirms Importance of Histology in Treatment of Non-Small Cell Lung Cancer With ALIMTA (pemetrexed for injection)
2. Study suggests blood test can help improve treatment outcomes for breast cancer patients
3. Study takes a step toward better defining fatigue
4. Having Less Power Impairs the Mind and Ability to Get Ahead, Study Shows
5. Study finds parents use cough medicines on under-2s despite the warnings
6. CardioDynamics Announces Significant ICG Study with Nearly Three Times the National Average Blood Pressure Control Rates at the American Society for Hypertension Annual Scientific Meeting
7. Study Supports Popular HIV Drug Regimen
8. Duska Therapeutics Sponsored University of Pennsylvania Study Demonstrates ATP Improves Sperm Motility and In Vitro Fertilization in Animals
9. Study shows that prostate cancer increases the risk of bone fracture
10. Study Suggests Green Tea May Support the Medical Treatment of Stomach and Colon Cancer
11. Forty-Five Percent of U.S. Employees Have Gained Weight at Their Current Jobs, CareerBuilder.com Study Finds
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:7/9/2014)... July 9, 2014 There has been a sharp ... Southwestern Medical Center using MyChart, the online, interactive service ... communicate with their healthcare providers, schedule appointments, and renew ... patients actively using MyChart each year increased ... increased more than 10-fold, according to a study by ...
(Date:7/9/2014)... watching World Cup highlights, Brian Williams refreshing old school ... positions on railings. A University of Colorado Cancer Center ... shows that YouTube also allows researchers, journals, and health ... of skin cancer and prevention. , "No matter what ... how we communicate around the world," says Chante Karimkhani, ...
(Date:7/9/2014)... of the most important organs in the human body. ... food properly this is its synthesis function ... this is its detoxification function. Lack of exercise ... damage the liver. The resulting diseased cells can lead ... liver failure. According to the German Liver Foundation, over ...
(Date:7/9/2014)... kidney and heart disease have raised concerns about the ... in the first study to look closely at this ... the University of Pennsylvania report that older kidney donors ... cardiovascular health as very healthy older people who did ... increasing organ transplant waitlists, the authors of the study ...
(Date:7/9/2014)... of allergic diseases has risen dramatically in Western societies. ... exposed to microorganisms and have fewer infections than previous ... A study by researchers at Sahlgrenska Academy, University of ... examine maturation of the immune system in relation to ... areas of the Vstra Gtaland Region, half of them ...
Breaking Medicine News(10 mins):Health News:MyChart use skyrocketing among cancer patients, UT Southwestern study finds 2Health News:MyChart use skyrocketing among cancer patients, UT Southwestern study finds 3Health News:Study of dermatology on YouTube shows new ways science reaches public 2Health News:Telemedicine for patients with chronic liver diseases 2Health News:Telemedicine for patients with chronic liver diseases 3Health News:Penn study finds living kidney donation does not increase risk of death or heart disease for older 2
... Survey finds children and their children are ... March 27 (HealthDay News) -- Alzheimer,s care in the ... suggests. , Three in five so-called "sandwich" caregivers who ... said their children help with care duties, ranging from ...
... Unveiling a Secure, Convenient Solution to Identify Blood ... BIO-key International,Inc. (OTC Bulletin Board: BKYI), a leader ... a proud sponsor at the spring,2008 AABB Conference ... association formerly known as the American Association of,Blood ...
... response to the growing,demand for solutions to ... United,States, a group of entrepreneurs has established ... consulting,firm with over 25 years experience in ... implement pharmaceutical care, and,"Inspire Pharmacists to Practice ...
... free dental screening, DALLAS, March 27 ... Computer Services, Inc. (ACS) will,sponsor free dental education ... 28. The event will be held for pupils ... in Dallas, starting at 9:00 a.m., The ...
... study ... participants, MINNEAPOLIS, ... Minnesota Cancer Center and ClearWay Minnesota(SM) found that,since the Freedom to ... significantly reduced exposure to a,tobacco-specific cancer causing chemical., The study ...
... Up, and Changes Lives, One Smile at ... a Time via Operation Smile Partnership, CINCINNATI, March 26 ... to host an upcoming award show,Samantha Harris knows firsthand the importance ... has partnered with Oral-B Satin,Floss to not only show people how ...
Cached Medicine News:Health News:With Alzheimer's, It Takes a Family 2Health News:With Alzheimer's, It Takes a Family 3Health News:BIO-key(R) to Sponsor and Exhibit at AABB Spring Conference 2Health News:BIO-key(R) to Sponsor and Exhibit at AABB Spring Conference 3Health News:Tabula Rasa Strategies(TM), LLC, Announces Their Company Launch - A 'Clean Slate' Approach to the Practice of Pharmaceutical Care 2Health News:Tabula Rasa Strategies(TM), LLC, Announces Their Company Launch - A 'Clean Slate' Approach to the Practice of Pharmaceutical Care 3Health News:ACS Expands National Dental Outreach Program to Dallas 2Health News:U of M Study Provides First Scientific Evidence That the Freedom to Breathe Act is Creating Healthier Workplaces for Hospitality Employees 2Health News:U of M Study Provides First Scientific Evidence That the Freedom to Breathe Act is Creating Healthier Workplaces for Hospitality Employees 3Health News:Samantha Harris and Oral-B Satin Floss Partner to Share Smiles 2Health News:Samantha Harris and Oral-B Satin Floss Partner to Share Smiles 3
(Date:1/15/2014)... Shire plc (LSE: SHP, NASDAQ: SHPG ) ... approval condition to the announced tender offer for all of the ... a result of the waiver, the transaction is no longer conditional ... on January 24, 2014 following the currently scheduled expiration time, subject ...
(Date:1/15/2014)... LOUISVILLE, Ky. , Jan. 15, 2014  Manufacturers, ... technologies must be able to protect their most ... (Logo: http://photos.prnewswire.com/prnh/20130716/CL46586LOGO ) Because ... Industry, it steadfastly remains one of the most ...
(Date:1/15/2014)... , Jan. 15, 2014 MultiCell Technologies, Inc. ... a U.S. provisional patent application concerning composition of matter, ... achieve targeted tumor cell death.  This ... noncoding double stranded RNA molecules (VSRNAs) which interfere with ...
Breaking Medicine Technology:Shire Waives OFT Condition Relating to the Acquisition of ViroPharma Inc. 2Shire Waives OFT Condition Relating to the Acquisition of ViroPharma Inc. 3Intellectual Property Insurance for Medical-related Products and Services 2MultiCell Technologies Files Patent Application Covering New Class of RNA Therapeutics 2MultiCell Technologies Files Patent Application Covering New Class of RNA Therapeutics 3
A rapid, convenient, qualitative method for detecting asymptomatic occult bleeding....
... die each year of colon cancer ... improvements (high contrast berium enema, colonoscopy, ... in the success rate of curative ... been achieved over the past two ...
... use of guaiac as a test for the ... of phenolic compounds present in guaiac to quinones, ... If blood is present, the heme portion of ... manner, catalyzing the release of oxygen from hydrogen ...
... SENSA elitewas designed to improve patient compliance. ... and sample collection options make this fecal ... understand and complete. Diet guidelines are explained ... determine which foods and drugs are okay ...
Medicine Products: