Navigation Links
Study shows that administering calcium and magnesium effectively reduces neurological sensitivity
Date:5/16/2008

ROCHESTER, Minn. -- Researchers in the North Central Cancer Treatment Group (NCCTG) have shown that patients who receive intravenous calcium and magnesium before and after the chemotherapy drug oxaliplatin for the treatment of advanced colon cancer experience a significantly reduced incidence and severity of neurological side effects (neurotoxicity). This reduction increases the likelihood that patients are able to complete a full course of treatment. The findings were released May 15 as part of the 44th annual meeting of the American Society of Clinical Oncology.

There have been limited studies and anecdotal stories about the effectiveness of calcium plus magnesium in reducing neurotoxicity caused by oxaliplatin, says Daniel Nikcevich, M.D., Ph.D., an oncologist at St. Marys Duluth Clinic in Duluth, Minn., a member of NCCTG and study co-chair.

We designed a double-blind, placebo-controlled study that confirmed the effectiveness of calcium plus magnesium in reducing debilitating neurological sensitivity associated with oxaliplatin, such as pain in the hands, fingers, feet and toes. In the past, these side effects have caused patients to stop treatment and, therefore, not receive critical therapy.

Each year in the United States, 150,000 patients are diagnosed with colon cancer, and approximately 50 percent of those develop advanced colon cancer. Oxaliplatin, in combination with other chemotherapy drugs such as 5-fluorouracil (5-FU), has emerged as a standard-of-care of first-line therapy for advanced colon cancer. However, oxaliplatin can cause both acute and chronic cumulative sensory neurological problems including pain, numbness and tingling that can prevent patients from completing treatment.

In the study, 50 of the 102 patients enrolled received intravenous calcium and magnesium along with oxaliplatin-based chemotherapy, while 52 patients received oxaliplatin-based adjuvant chemotherapy for colon cancer and an intraven
'/>"/>

Contact: Traci Klein
newsbureau@mayo.edu
507-284-5005
Mayo Clinic
Source:Eurekalert

Page: 1 2

Related medicine news :

1. ASCO Study Confirms Importance of Histology in Treatment of Non-Small Cell Lung Cancer With ALIMTA (pemetrexed for injection)
2. Study suggests blood test can help improve treatment outcomes for breast cancer patients
3. Study takes a step toward better defining fatigue
4. Having Less Power Impairs the Mind and Ability to Get Ahead, Study Shows
5. Study finds parents use cough medicines on under-2s despite the warnings
6. CardioDynamics Announces Significant ICG Study with Nearly Three Times the National Average Blood Pressure Control Rates at the American Society for Hypertension Annual Scientific Meeting
7. Study Supports Popular HIV Drug Regimen
8. Duska Therapeutics Sponsored University of Pennsylvania Study Demonstrates ATP Improves Sperm Motility and In Vitro Fertilization in Animals
9. Study shows that prostate cancer increases the risk of bone fracture
10. Study Suggests Green Tea May Support the Medical Treatment of Stomach and Colon Cancer
11. Forty-Five Percent of U.S. Employees Have Gained Weight at Their Current Jobs, CareerBuilder.com Study Finds
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:3/2/2015)... 2015 Robins & Morton Celebrates Women ... Women in Construction Week (March 1-7, sponsored by the ... National Women’s History Month, Robins & Morton is recognizing ... company and the construction industry as a whole. From ... dozens of roles in between, each woman has a ...
(Date:3/2/2015)... 2015 The Workgroup for Electronic Data ... use of health IT to create efficiencies in healthcare ... for Small Providers.” The white paper by WEDI’s ICD-10 ... for ICD-10 testing by focusing on primary considerations and ... with the October 1, 2015 implementation date. Download the ...
(Date:3/2/2015)... March 02, 2015 This year, the National ... and will provide opportunities for people across the country to ... help people with MS live their best lives. MS Awareness ... to inspire others to join the Society’s vision of a ... unpredictable, often disabling disease of the central nervous system, interrupts ...
(Date:3/2/2015)... 2015 Four Seasons Resort Maui at Wailea, ... anniversary this year, having officially opened its doors on March ... is honoring over 70 employees who started on Day 1 ... the approximately 400 original employees. The celebration will be ... , This Four Seasons flagship resort, the first ...
(Date:3/2/2015)... What are the best practices for writing a ... interviews scheduled, how can physicians best prepare, and how ... physicians who are looking for new opportunities can learn ... PracticeLink Physician Career Advancement Workshop and Job Fair on ... 5:30 to 8:30 p.m. at the Marriott-Texas Medical Center ...
Breaking Medicine News(10 mins):Health News:Robins & Morton Recognizes Women In Construction 2Health News:WEDI Releases New White Paper on ICD-10 Testing for Small Providers 2Health News:Every Connection Counts During MS Awareness Week 2Health News:Every Connection Counts During MS Awareness Week 3Health News:Every Connection Counts During MS Awareness Week 4Health News:Celebrating Four Seasons Resort Maui’s 25th Anniversary 2Health News:PracticeLink to Host a Career Advancement Workshop and Job Fair in Houston 2
... Ablation Frontiers, Inc., a,privately-held medical device company, ... using the company,s Tip-Versatile Ablation,Catheter(TM) (T-VAC). Dr. ... in,Chertsey, United Kingdom is one of three ... new multi-electrode linear ablation catheter since,November 2007. ...
... One of Australia,s largest,pharmacy groups, Chemmart, has introduced a ... posed by discount chains., The system was launched ... participating pharmacies signed up more than 30,000 Chemmart,"rewards" members., ... has now been,rolled out to more than 160 Chemmart ...
... 16 The Ninth Annual Renal Teen,Prom, "Winter ... is,to be held Sunday, January 20, 2008 at ... unique event attracts more than 350 kidney teens,(ages ... a transplant, and,their guests, coming from Washington D.C., ...
... Americans consume more calories as a,nation on Super Bowl Sunday ... the time the final whistle blows at Super Bowl XLII,Americans ... chicken wings, and beer., But this year you have ... field 109 times to burn off all of those extra ...
... life for kids with moderate to severe disease, , , ... significantly improved psoriasis symptoms in children under 17 with ... The study found that 57 percent of the children ... a 75 percent improvement in their symptoms, and their ...
... a 23% reduced risk of falling in winter, spring ... may help reduce the risk of falls among high-risk elderly ... than 65 fall each year, and six percent sustain a ... of falling is a major problem in older people," according ...
Cached Medicine News:Health News:Speedy Procedures Demonstrate Excitement and Continued Interest in Novel Multi-Electrode Ablation System 2Health News:Chemmart(R) Sees Instant Results From Launch of New Rewards Program 2Health News:Celebrities to Attend the Ninth Annual Kidney Teen Prom 2Health News:Eat This, Not That!(TM): 5 Smart Super Bowl Swaps That Will Save You Hundreds of Calories 2Health News:Adult Drug Effective in Treating Psoriasis in Children 2Health News:Adult Drug Effective in Treating Psoriasis in Children 3Health News:Vitamin D May Curb Falls in High-Risk Older Women 2
(Date:3/2/2015)... BETHESDA, Md. , March 2, 2015 ... on treating and preventing autoimmune diseases, announced today that ... (AMG 714) from Amgen (NASDAQ: AMGN ). ... has the rights to develop, manufacture and commercialize AMG ... . Concurrently, Amgen has been granted an exclusive ...
(Date:3/2/2015)... Texas , March 2, 2015   Lexicon ... biopharmaceutical company focused on developing breakthrough treatments for human ... 2014 financial results on Wednesday, March 4, 2015 before ... conference call and webcast to discuss clinical development progress ... end of 2014 at 10:00 a.m. Eastern Time on ...
(Date:3/2/2015)... 2, 2015  BioMed Realty Trust, Inc. (NYSE: ... 313,000 square feet of space in the most dynamic ... world through the termination of Vertex Pharmaceuticals, leases on ... effective February 28, 2015. BioMed Realty will receive a ... begin to reposition the properties to meet the growing ...
Breaking Medicine Technology:Celimmune Announces Anti-IL-15 Antibody Licensing and Option Agreements with Amgen 2Celimmune Announces Anti-IL-15 Antibody Licensing and Option Agreements with Amgen 3Lexicon To Report Fourth Quarter And Year End 2014 Financial Results On March 4, 2015 2BioMed Realty Gets Back 313,000 Square Feet Of Valuable Real Estate In Cambridge Innovation District 2BioMed Realty Gets Back 313,000 Square Feet Of Valuable Real Estate In Cambridge Innovation District 3
... 13 Anadys Pharmaceuticals, Inc. (Nasdaq: ANDS ) ... Annual Healthcare Conference on Friday, September 17, 2010 at 8:35 ... at the Four Seasons in Boston.  Steve Worland, Ph.D., President ... of Anadys and its clinical development programs. Dr. ...
... Amgen (Nasdaq: AMGN ) will participate in ... the St. Regis New York in New York City, beginning ... president of Global Development, for Amgen, will present at the ... the Internet and can be accessed from Amgen,s website, ...
Cached Medicine Technology:Anadys Pharmaceuticals to Present at Two Upcoming Investor Conferences 2
... nebulizer system offers an affordable and ... COPD or other respiratory conditions. The ... gives patients the ability to take ... Its unique nebulizer design delivers powerful ...
... The most compact, portable DC powered ... Elite provides the freedom to take ... system is powered by the included ... Adapter and Battery Kit. The integral ...
... The 50 psi MaxiCompressor, the ... to run 24 hours a ... It features a tamper-proof locking ... unintentional increases or decreases in ...
... PulmoStar is a low cost compressor/nebuliser which offers ... the home, health centre or clinic. The SunMist ... and a simple filter change every six months., ... With Disposable Neb, 3 Prong Polarized plug With ...
Medicine Products: