Navigation Links
Study shows surgery provides good long-term outcomes for patients with gastrointestinal cancers

CHICAGO (January 14, 2009) New research published in the January issue of the Journal of the American College of Surgeons shows that laparoscopic removal of gastrointestinal stromal tumors (GISTs) is safe and effective, with a disease-free survival rate of nearly 80 percent after an average follow-up time of three and a-half years.

GIST is a type of cancer arising from special cells in the wall of the gastrointestinal tract that help coordinate the muscular movement of digestive organs. Each year, between 4,500 and 6,000 cases of GIST are diagnosed in the United States. Laparoscopic surgery is an attractive alternative to traditional "open" surgery the treatment of choice for GISTs that have not spread to nearby organs since it is requires smaller abdominal incisions and therefore may be safer and result in a quicker recovery.

"Based on our data, which represents the largest retrospective series of GIST patients reported to date, we believe that laparoscopic resection is feasible in the management of these tumors, carries no additional risks and has comparable results to the open approach," said Celia Divino, MD, FACS, Chief, Division of General Surgery at The Mount Sinai Medical Center, New York, N.Y.

Parissa Tabrizian, MD, further noted that, "The biologic behavior of GISTs makes them amenable to laparoscopic resection because they do not require removal of large amounts of tissue or lymph nodes."

Researchers conducted a retrospective study to evaluate long-term outcomes and survival in 76 patients who underwent laparoscopic treatment of GIST. Tumors were located in the stomach (72 percent) and the small bowel (28 percent).

At a mean follow-up of 41 months (range, 3 to 102 months), the overall disease-free survival rate was 78 percent (77 percent for gastric tumors and 82 percent for small bowel tumors). Three percent of patients died of metastatic disease, and nine percent of patients died from other unrelated causes. In comparison with patients with gastric GISTs, those with small bowel tumors had overall better outcomes, with no deaths or disease recurrence. Recurrent disease was seen in four patients with gastric tumors, and there was disease-specific mortality in two patients. There was no difference in overall survival between patients with small bowel and gastric tumors (89.5 percent versus 88.7 percent, respectively, p>0.165).


Contact: Sally Garneski, ACS
Weber Shandwick Worldwide

Related medicine news :

1. TPHAC Reaction to Economic Impact Study
2. First-of-Its Kind Study: Medicare for All (Single-Payer) Reform Would Be Major Stimulus for Economy With 2.6 Million New Jobs, $317 Billion in Business Revenue, $100 Billion in Wages
3. National Children's Study Begins Recruiting Volunteers
4. Study shows workplace benefits of influenza vaccination in 50-64 year olds
5. Study: Most young violent offenders in two NYC neighborhoods have seen someone killed
6. National Childrens Study Begins Recruiting Volunteers
7. InNexus Biotechnology Completes Preclinical Study Confirming in Vivo Effectiveness and Safety of Lead Candidate DXL625, Schedules Meeting With FDA
8. UNC study supports role of circadian clock in response to chemotherapy
9. Medical study shows epidurals and spinal anesthetics are safer than previously reported
10. InterMune Reports Results from Triple Combination Study of ITMN-191
11. LegalView Reports Traumatic Brain Injury Study Concluding Spirituality Increases Following Brain Damage
Post Your Comments:
(Date:10/13/2017)... ... , ... Talented host, actor Rob Lowe, is introducing a ... episode of "Success Files," which is an award-winning educational program broadcasted on PBS ... in-depth with passion and integrity. , Sciatica occurs when the sciatic nerve in ...
(Date:10/13/2017)... ... October 13, 2017 , ... “The Journey: From the Mountains to the Mission ... lost souls in the Philippines. “The Journey: From the Mountains to the Mission Field” ... the Bible. She has taught all ages and currently teaches a class of ladies ...
(Date:10/12/2017)... ... October 12, 2017 , ... First Healthcare ... program management, will showcase a range of technology and learning solutions at the ... Convention and Expo to be held October 14–18, 2017 at the Mandalay Bay ...
(Date:10/12/2017)... ... , ... Planet Fitness, one of the largest and fastest growing franchisors and ... flagship location in Covington, LA at 401 N. U.S. Highway 190, in January of ... Depot in the Holiday Square shopping center. Its location allows it to serve both ...
(Date:10/12/2017)... ... 2017 , ... IsoComforter, Inc. ( ), one of the ... new design of the shoulder pad. The shoulder pad provides optimal support and ... pain while using cold therapy. By utilizing ice and water that is circulated from ...
Breaking Medicine News(10 mins):
(Date:10/2/2017)... Halo Labs announces the European launch of their new low volume, ... 2017 in Cambridge, U.K on October 4th. ... samples with unprecedented speed and sensitivity while using far less sample ... ... system ...
(Date:9/27/2017)... YORK , Sept. 27, 2017  DarioHealth Corp. (NASDAQ: DRIO), a ... today announced that its MyDario product is expected to appear on The ... when The Dr. Oz Show airs in your area: ... The nine-time Emmy award-winning, The Dr. Oz ... The ...
(Date:9/22/2017)... 22, 2017 AVACEN Medical (AVACEN) announced that ... successfully helping those with the widespread pain associated with ... Amanda in Essex, England commented, ... hair, experiencing no sleep at all, tremendous pain, with ... cannot recommend [the AVACEN 100] enough, how this has ...
Breaking Medicine Technology: