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Study shows on-pump bypass comparable to off-pump at year mark
Date:3/11/2013

SAN FRANCISCO (March 11, 2013) Patients who underwent heart bypass surgery without a heart- lung machine did as well one year later as patients whose hearts were connected to a pump during surgery in a study presented today at the American College of Cardiology's 62nd Annual Scientific Session.

CORONARY, an international, multicenter trial of on-pump (with a heart-lung machine) versus off-pump bypass surgery, enrolled 4,752 patients already scheduled to undergo a bypass procedure. The study is the largest to compare the two approaches.

For the primary endpoint of patients' composite outcomes of death, stroke, heart attack or new kidney failure requiring dialysis within one year of surgery, researchers found no significant difference between patients receiving the off-pump and on-pump procedures (12.2 vs. 13.3 percent, p = 0.24.) The study previously looked at this primary endpoint for patients at 30 days and also found the two methods to be statistically neutral in the short-term, but conflicting results from other research studies raised uncertainty about patients' intermediate (one year post-surgery) and long-term outcomes.

"We found that both on-pump and off-pump bypass have similar results, even at one year," said Andre Lamy, MD, lead author of the CORONARY study and professor in the division of cardiac surgery at McMaster University in Ontario. "Both surgical approaches are effective when provided by experienced surgeons."

Coronary artery bypass graft surgery (CABG) is one of the most commonly performed operations in the U.S. and the world and consumes more resources in cardiovascular medicine than any other procedure. In on-pump CABG, the patient's heart is stopped and blood is circulated through a heart-lung machine, where it is oxygenated and returned to the patient. In the off-pump technique, the surgeon uses a retractor to lift the still-beating heart and perform all coronary artery grafts. Off-pump CABG eliminat
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Contact: Beth Casteel
bcasteel@acc.org
240-328-4549
American College of Cardiology
Source:Eurekalert

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