Navigation Links
Study shows link between sleep apnea and hospital maternal deaths

Tampa, FL (May 2, 2014) -- Pregnant women with obstructive sleep apnea are more than five times as likely to die in the hospital than those without the sleep disorder, a comprehensive national study by the University of South Florida researchers found.

Among delivery-related hospital discharges, sleep apnea was also associated with an increase in severe medical conditions that are top causes of maternal death, including preeclampsia, eclampsia, an enlarged heart and pulmonary blood clots, reported the study published online this month in the journal SLEEP.

Sleep apnea causes repeated awakenings and pauses in breathing during the night. Previous smaller studies have found that the condition increases the risk for poor pregnancy outcomes, including preeclampsia (high blood pressure in pregnancy associated with loss of protein in the urine), restricted growth of the fetus, preterm delivery and gestational diabetes. Obesity appears to contribute to the adverse effects.

However, the USF study provided the first large-scale U.S. analysis of the association between sleep apnea and maternal deaths.

"The astounding association with maternal death was surprising," said lead author Judette Louis, MD, MPH, assistant professor of obstetrics and gynecology at the USF Health Morsani College of Medicine who works out of Tampa General Hospital. "I did not expect to find such a difference in mortality between pregnant women who had sleep apnea and those who did not, especially when we controlled for obesity and other complicating factors.

While more study is needed, the increased likelihood of death for those with sleep apnea may be explained in part by the physiological demands of pregnancy, she said. "Underlying damage or chronic disease caused by sleep apnea may be exacerbated by the stresses of pregnancy."

Maternal death rates have increased slightly in recent years, and obesity is one suspected reason.

"Our study indicates that sleep apnea may also play a role, whether a woman is obese or not," said Dr. Louis, who holds a joint appointment in the USF College of Public Health's Department of Community and Family Health. "It's important for obstetricians and primary care practitioners to identify sleep apnea in younger women of reproductive age, convey its risk, and treat the condition before pregnancy."

The researchers drew upon a nationally representative sample of 55 million maternal-related hospital discharges from 1998 to 2009 women who were pregnant or gave birth while in the hospital. They identified those with sleep apnea diagnoses and examined the links between this sleep-disordered breathing and poor pregnancy health outcomes, including in-hospital deaths.

Among the retrospective study's findings:

  • Women with sleep apnea during pregnancy were more likely to experience serious medical conditions and pregnancy-related complications than women without sleep apnea diagnoses.

  • The strongest associations were with the following medical conditions: cardiomyopathy (an enlarged heart), heart failure and pulmonary edema (fluid build-up in the lungs).

  • Among pregnancy-related complications, sleep apnea was associated with a greater likelihood of eclampsia and preeclampsia as well as gestational diabetes and gestational high blood pressure, even after controlling for obesity.

  • Even after adjusting for potentially life-threatening cardiovascular and metabolic conditions, women with sleep apnea were five times more likely to die before discharge from the hospital than their counterparts without sleep apnea.

  • The increase in the rate of sleep apnea among pregnancy-related discharges over the study period coincided with a rise in obesity rates.

  • With the exception of cesarean delivery, gestational hypertension and stillbirth, the likelihood of potentially life-threatening illnesses and maternal death were higher for women with sleep apnea irrespective of obesity.

  • The presence of obesity appeared to intensify the effects of risks of cardiovascular disease in pregnant women with sleep apnea.


Contact: Anne DeLotto Baier
University of South Florida (USF Health)

Related medicine news :

1. Vanderbilt study explores genetics behind Alzheimers resiliency
2. Study: Custom-made mouthguards reduce athletes risk of concussion
3. Study: Low-fat diet helps fatigue in people with MS
4. Space Station study seeks how plants sense up and down
5. Study confirms increased prevalence of GI symptoms among children with autism
6. Anti-smoking TV ads should use anger, Dartmouth-Cornell study suggests
7. $2.3M study to examine how neighborhoods influence child maltreatment rates
8. Treat homelessness first, everything else later: Study
9. NYU Steinhardt researchers to study why male millennials risk HIV transmission
10. Study finds almost half of homeless men had traumatic brain injury in their life
11. Study finds almost half of homeless men had traumatic brain injury in their
Post Your Comments:
Related Image:
Study shows link between sleep apnea and hospital maternal deaths
(Date:10/13/2015)... Angeles, CA (PRWEB) , ... October 13, 2015 , ... ... To incentivize would-be customers, eMarketing Concepts began a $1 promotion – effectively offering all ... a resounding success, and within weeks the company was flooded with phone calls from ...
(Date:10/13/2015)... ... 13, 2015 , ... The Bill Howe Family of Companies is an award ... and flood remediation services. Family-owned and operated for 35 years, they have maintained value, ... Diego plumber two years in a row from the Union Tribune Reader’s Poll, a ...
(Date:10/12/2015)... , ... October 13, 2015 , ... ... its biannual Heroes in Recovery Awards at Foundations Recovery Network’s Moments of Change ... presented the one-of-a-kind awards to Noah Levine and Dean Dauphinais who exemplify the ...
(Date:10/12/2015)... North Carolina (PRWEB) , ... October 12, 2015 , ... Kevin Costello, winner of the ... North Carolina , embarks today for his dream vacation to Hawaii. , “I didn’t believe ... worked out,” he says. “This contest encouraged me to get to the gym and invest ...
(Date:10/12/2015)... ... 2015 , ... The American Society of Clinical Hypnosis (ASCH) ... and clinical training in a health care discipline. , Many practitioners claim ... losing weight, managing pain, or stopping smoking, etc. Frequently, extravagant statements and guarantees ...
Breaking Medicine News(10 mins):
(Date:10/12/2015)... Ga. , Oct. 12, 2015  MiMedx Group, ... company utilizing human amniotic tissue and patent-protected processes to ... Wound Care, Surgical, Orthopedic, Spine, Sports Medicine, Ophthalmic, and ... revenue results for the third quarter of 2015, its ... the Company has secured a $50 million Senior Secured ...
(Date:10/12/2015)... -- This study focuses on China,s ... past decades, the industry has been growing at a fast ... consumer consumptions in China have transformed ... China is one of the world,s major producers ... the world, China is the world,s ...
(Date:10/12/2015)... SACRAMENTO, Calif. , Oct. 12, 2015  In ... month in the Journal of Neurology, Neurosurgery, and Psychiatry, ... to reduce brain atrophy and cognitive decline in patients ... --> --> IVIG, extracted ... contains antibodies to amyloid, an abnormal brain protein found ...
Breaking Medicine Technology: