Navigation Links
Study shows lifetime effects of pediatric liver transplants
Date:3/26/2008

Parents of pediatric liver transplant recipients report lower health-related quality of life for their children two years after the surgery, compared to reports from the parents of healthy children. However, reports of family dysfunction fall within the normal range. These findings are published in the April issue of Liver Transplantation. The article is also available online at Wiley Interscience (www.interscience.wiley.com ).

Children account for up to 15 percent of liver transplant recipients each year in the U.S. Their 10-year survival rate is nearly 80 percent, however, survival is not the only outcome of interest. Liver transplantation has long-term implications for a childs health related quality of life (HRQOL), which includes physical health, mental health, social functioning, role functioning and general health perceptions.

Previous studies have attempted to measure the HRQOL of pediatric liver transplant recipients, but have been limited to single centers and have yielded mixed results. Researchers from the Studies of Pediatric Liver Transplantation (SPLIT) consortium, led by Estella Alonso of Childrens Memorial Hospital in Chicago, decided to conduct a multi-center analysis of HRQOL and family function for these young patients.

They included 102 pediatric liver transplant recipients from five centers in the United States. Sixty-seven were under 5 years old, while 35 were between 5 and 18 years of age. At about 2 years post transplant, the researchers asked the childrens parents to complete a questionnaire about their childs quality of life, along with the Family Assessment Devise (FAD), assessing family function. They then compared the data to either a control population or a published healthy normative population.

On measures of HRQOL, the younger transplant recipients scored significantly lower in global health, general health perceptions and change in health, compared to the children in the control group. The older children scored significantly lower in physical health, general health, parental emotional impact, and disruption of family activities.

Interestingly, however, the mean scores of the FAD scales indicated no increase in family dysfunction. Twenty-five percent of the transplant families were within the unhealthy range, compared to 19 to 36 percent of non-clinical families reported in FAD validation studies.

Future assessments of HRQOL in this population should include the perspective of the patient and both of their parents to yield the fullest understanding of their health status and adjustment to post-transplant medical care, the authors conclude.


'/>"/>

Contact: Sean Wagner
swagner@bos.blackwellpublishing.com
781-388-8550
Blackwell Publishing Ltd.
Source:Eurekalert

Related medicine news :

1. New Study -- Same Result! Comprehensive Sex Education Works
2. New study suggests that specially-formulated
3. Study: Pregnant Women Who Eat More Fish, Including Canned Tuna, Have Smarter Children
4. Study finds certain liver disease related to cardiovascular fitness
5. Study: Dramatic rise in hepatitis C-related deaths in the United States
6. St. Jude study offers new hope for children with kidney tumors deemed inoperable
7. U.S. Army Study Reports WoundStat(TM) is Most Effective
8. APIC Launches First National C. Difficile Prevalence Study
9. New Lung Association Study Shows $142 Billion Benefit of Converting to Zero-Emission Vehicles by 2030
10. APIC launches first national C. difficile prevalence study
11. Cato Study Finds Iran a Surprising Model for Kidney Markets
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:12/7/2016)... ... 2016 , ... The Business Architecture Guild is ... on March 21-22, 2017. This premier event features business practitioners and experts from ... of industries such as financial services, insurance, healthcare, manufacturing, transportation, retail, and utilities. ...
(Date:12/7/2016)... San Mateo, CA (PRWEB) , ... December 07, 2016 , ... ... entire San Francisco Peninsula region, is proud to announce new city-specific pages as part ... care services for the elderly, they often look, first, for local agencies serving their ...
(Date:12/6/2016)... ... 06, 2016 , ... People with Parkinson’s disease and cognitive ... type of MRI, according to a study appearing online in the journal Radiology. ... characterized by tremors or trembling and stiffness in the limbs, impaired balance and ...
(Date:12/6/2016)... ... December 06, 2016 , ... Men with gum disease ... of serious health problems, such as cardiovascular illness, according to research cited in ... Hills Periodontics & Dental Implant Center notes that the correlation between periodontal disease ...
(Date:12/6/2016)... ... December 06, 2016 , ... According to a November 1 article ... too many mints or not drinking enough water, which can cause bad breath (known ... notes that good oral hygiene not only helps reduce the possibility of bad breath, ...
Breaking Medicine News(10 mins):
(Date:12/7/2016)... 7, 2016 The global  ... value of USD 3.9 billion by 2024, based ... Inc. The growth of the market is attributed ... technological advancements by the market players. Demand for ... increasing donation, rising awareness about transfusion-transmitted diseases, and ...
(Date:12/6/2016)... -- Licenders is bringing their 100% all-natural lice removal service to ... 203 13 th Street was specifically chosen to make treatment ... "Our goal is to ease parents, stress and bring their lives ... right back to class without skipping a beat. The best part ... the whole family," Licenders President Adie Horowitz states. ...
(Date:12/6/2016)... 6, 2016  Alopexx Oncology, LLC announced data from ... fusion protein (immunocytokine) composed of interleukin-2 and a CD20-targeting ... on B cells as Rituxan and maintains the activities ... also involved in tumor targeting, engagement of the immune ... results of the study (abstract #95954) were presented at ...
Breaking Medicine Technology: