Navigation Links
Study shows how vitamin E can help prevent cancer
Date:3/14/2013

COLUMBUS, Ohio Researchers have identified an elusive anti-cancer property of vitamin E that has long been presumed to exist, but difficult to find.

Many animal studies have suggested that vitamin E could prevent cancer, but human clinical trials following up on those findings have not shown the same benefits.

In this new work, researchers showed in prostate cancer cells that one form of vitamin E inhibits the activation of an enzyme that is essential for cancer cell survival. The loss of the enzyme, called Akt, led to tumor cell death. The vitamin had no negative effect on normal cells.

"This is the first demonstration of a unique mechanism of how vitamin E can have some benefit in terms of cancer prevention and treatment," said lead author Ching-Shih Chen, professor of medicinal chemistry and pharmacognosy at The Ohio State University and an investigator in Ohio State's Comprehensive Cancer Center.

The study appears in the March 19, 2013, issue of the journal Science Signaling.

Chen cautioned that taking a typical vitamin E supplement won't offer this benefit for at least two reasons: The most affordable supplements are synthetic and based predominantly on a form of the vitamin that did not fight cancer as effectively in this study, and the human body can't absorb the high doses that appear to be required to achieve the anti-cancer effect.

"Our goal is to develop a safe pill at the right dose that people could take every day for cancer prevention. It takes time to optimize the formulation and the dose," he said.

Chen has filed an invention disclosure with the university, and Ohio State has filed a patent application for the agent.

Vitamin E occurs in numerous forms based on their chemical structure, and the most commonly known form belongs to a variety called tocopherols. In this study, researchers showed that, of the tocopherols tested, the gamma form of tocopherol was the most p
'/>"/>

Contact: Ching-Shih Chen
chen@pharmacy.ohio-state.edu
614-688-4008
Ohio State University
Source:Eurekalert

Page: 1 2 3

Related medicine news :

1. Study Suggests Vaccine May Help Kids With Brain Cancer
2. Study reveals how cancer drug causes diabetic-like state
3. Coffee Drinking in Pregnancy Wont Lead to Sleepless Baby: Study
4. Lower GI problems plague many with rheumatoid arthritis, Mayo Clinic study finds
5. Veggies Like Broccoli, Cabbage May Help Fight Breast Cancer: Study
6. No Added Cancer Risk From Hip Replacement Materials: Study
7. Reported Decline in U.S. Pneumonia Deaths May Be False: Study
8. Early Study Finds Some Promise for Lung Cancer Vaccine
9. Narcissists Often Ace Job Interviews, Study Finds
10. Sexual objectification of female artists in music videos exists regardless of race, MU study finds
11. Soy may alleviate hot flashes in menopause, large-scale study finds
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:4/26/2015)... Italian public health researchers have released new data ... and other asbestos-related industries. Surviving Mesothelioma has just posted ... to read it now. , University researchers ... Medicine analyzed more than 15,000 cases of mesothelioma between ... asbestos cancer was most common. , “Asbestos cement ...
(Date:4/26/2015)... From March 18th, 2015 toward the ... Master™ Dahryn Trivedi, spent a month traveling in India ... institutions in the efforts of creating highly advanced, effective ... for human health care. , During their journey, ... institutions. All lab facilities are approved by the U.S. ...
(Date:4/26/2015)... In an article published last month in ... biomechanics occurring during the use of handheld electronic devices such ... that use of a tablet increases mechanical demand on neck ... more than when the neck is in a neutral position. ... pointing out the potential hazards of overuse of mobile technology ...
(Date:4/25/2015)... The National League for Nursing's ... endeavor to prepare nurses to provide high quality, culturally ... according to a new report by the John A. ... , The project began in 2007 as a ... direction of Elaine Tagliareni, EdD, RN, CNE, FAAN, professor ...
(Date:4/25/2015)... The Hon. Ellen Tauscher, Independent Chair ... following statement following the deadly earthquake in Nepal: , ... in the deaths of more than 1,000 people. ... Nepal, Bangladesh, India and other parts of South Asia. ... the people of Nepal and the families of the ...
Breaking Medicine News(10 mins):Health News:New Investigation Finds Mesothelioma “Clusters” Around Italian Cement Plants, According to Surviving Mesothelioma 2Health News:Trivedi Science™ Has Started Scientific Research to Create More Effective Pharmaceuticals and Nutraceuticals 2Health News:Trivedi Science™ Has Started Scientific Research to Create More Effective Pharmaceuticals and Nutraceuticals 3Health News:Avoiding the Pain in the Neck Caused by Overuse of Technology 2Health News:Avoiding the Pain in the Neck Caused by Overuse of Technology 3Health News:Avoiding the Pain in the Neck Caused by Overuse of Technology 4Health News:Hartford Foundation Report Details Success of NLN's Advancing Care Excellence for Seniors (ACE.S) Program 2Health News:Hartford Foundation Report Details Success of NLN's Advancing Care Excellence for Seniors (ACE.S) Program 3
... Feb. 7 PartnerRe Ltd.,(NYSE: PRE ) announced ... the period December 1, 2007 - February 29, 2008 ... Cumulative Redeemable Preferred Shares, and,$0.40625 per share on the ... will be payable on March 3, 2008, to,shareholders of ...
... NHS Choices ( http://www.nhs.uk ), the,online ,front door, ... information,resource, Health A-Z, aimed to help people find ... Based on NHS accredited information, the A-Z directory,( ... on a topic in seconds, providing them with ...
... that run on both conventional gasoline and stored ... gap until more sustainable technology is developed, according ... publication International Journal of Automotive Technology and Management, ... even slow development of more sustainable fuel-cell powered ...
... release was issued,today jointly by Schiffrin Barroway Topaz & ... DISTRICT COURT DISTRICT OF MARYLAND (NORTHERN DIVISION), ... LITIGATION Civil Action No. MJG 05-1224, SUMMARY ... ALL PERSONS AND ENTITIES WHO PURCHASED OR OTHERWISE ACQUIRED ...
... Comes With Software that Provides Hands-on Learning, ... a patient,s,medical records is essential to quality medical ... and death of a patient. Electronic Health,Record (EHR) ... make patient history readily available in those critical ...
... Environmental Health Groups Call for Immediate Moratorium on Bisphenol,A ... CHURCH, Va., Jan. 7 Dozens of state,and national ... for an immediate moratorium on the use of bisphenol ... containers, based on the results of a,new study that ...
Cached Medicine News:Health News:The trouble with hybrids 2Health News:Summary Notice of Proposed Settlement and Settlement Hearing in Re Martek Biosciences Corp., Securities Litigation 2Health News:McGraw-Hill Higher Education Publishes Text on Innovative Electronic Health Records System 2Health News:Baby Bottles Leach Toxic Chemical, According to New U.S. and Canadian Study 2Health News:Baby Bottles Leach Toxic Chemical, According to New U.S. and Canadian Study 3Health News:Baby Bottles Leach Toxic Chemical, According to New U.S. and Canadian Study 4
(Date:4/24/2015)...  Novartis Pharmaceuticals Corporation (NPC) has been named the top ... on the annual DiversityInc Top 50 Companies for Diversity listing. ... for Diversity on April 23 at an awards ceremony in ... second on the DiversityInc Top 10 Companies for Recruitment list ... Groups list. David Epstein , Division ...
(Date:4/24/2015)... , April 24, 2015  Lannett Company, Inc. (NYSE: ... and increased its five-year revolving credit facility to $120 ... accordion feature that will allow the company to increase ... $30.0 million, subject to securing additional commitments from existing ... the credit facility remains December 18, 2018.   ...
(Date:4/24/2015)... Spain , April 24, 2015  Elekta has ... Monaco® treatment planning system , enabling European clinics ... supports major treatment techniques including advanced 3D planning, IMRT, ... system. Monaco ... as well improved workflow efficiency. Advancements in 3D planning ...
Breaking Medicine Technology:Novartis Pharmaceuticals Corporation is first company to receive number one ranking two years in a row on DiversityInc Top 50 Companies for Diversity list 2Novartis Pharmaceuticals Corporation is first company to receive number one ranking two years in a row on DiversityInc Top 50 Companies for Diversity list 3Novartis Pharmaceuticals Corporation is first company to receive number one ranking two years in a row on DiversityInc Top 50 Companies for Diversity list 4Lannett Expands Revolving Credit Facility To $120 Million 2Elekta CE marks for Monaco v5.10 treatment planning system 2
... VALLEY FORGE, Pa., June 13, 2011 Saint-Gobain ... adding a variety of ergonomic features that improve ... and solution storage applications. These improvements are based ... laboratory and pharmaceutical environments. Manufactured from ...
... Today Divine Skin Inc. (DSKX), a developer of ... analgesic intended to compete over the counter with the ... to begin shipping upon final authorization by the Drug ... on underserved and niche categories, of course our pain ...
Cached Medicine Technology:New Bio-Simplex™ Polypropylene Carboys Feature Ergonomic Design, Versatile Closure Options 2New Bio-Simplex™ Polypropylene Carboys Feature Ergonomic Design, Versatile Closure Options 3Divine Skin Announces New Pain Reliever to Compete With Tylenol, Advil, Aspirin 2Divine Skin Announces New Pain Reliever to Compete With Tylenol, Advil, Aspirin 3
... Vitamin D kit is an enzymeimmunoassay for ... hydroxylated metabolites in serum or plasma. Calibrators, ... labelled 25-OH D. The diluted samples are ... with a highly specific sheep 25-OH D ...
... for the control of glucose metabolism. It ... of Langerhans as the precursor, proinsulin, which is ... are secreted in equimolar amounts into the portal ... of two polypeptide chains, the A-chain and B-chain ...
... is an integral part of the enzymatic ... II as well as the degradation of ... ACE is primarily located in endothelial cells. ... parameter for sarcoidosis and myocardial infarction but ...
... Retinol binding Proetin (RBP) is small (21kD) ... complex with pre-albumin in blood but loses ... been deliverd to the target cells. The ... the glomerulus and catabolized in the,renal tubules ...
Medicine Products: