Navigation Links
Study shows how Salmonella survives in environment
Date:3/23/2009

Scientists at the University of Liverpool have demonstrated how a single-celled organism, living freely in the environment, could be a source of Salmonella transmission to animals and humans.

Salmonella are microscopic living creatures that can contaminate almost any food type, causing diarrhoea, abdominal pain and fever. Scientists know that Salmonella which can also cause typhoid fever has evolved unique mechanisms to prevent the body's immune system from functioning effectively, but until now it was not understood how it survives so successfully in the environment.

Scientists at Liverpool, in collaboration with the Institute for Animal Health, have shown that Salmonella use a secretion system to protect themselves inside amoeba a single-celled organism living on land and in the water. The research suggests that amoeba may be a major source of Salmonella within the environment and could play a significant role in transmission of infection to man and animals.

Salmonella uses a system, called SP12 type III, which acts as a bacterial machine inside organisms and causes disease in humans, animals and plants. The system employs a 'syringe-like' mechanism to inject bacteria into cells that would normally release compounds to rid the body of harmful substances. This system changes the structure of the cell and prevents these compounds from coming into contact with pathogens and destroying them.

Dr Paul Wigley, from the National Centre for Zoonosis Research, based at the University's Leahurst campus, explains: "Salmonella has managed to survive extremely successfully in the environment, finding its way into our food and causing illness, despite the body's best efforts to fight it off. We found that it uses a system which operates in the human immune system as well as inside amoeba living in the environment. This system essentially protects Salmonella within cellular compartments, called phagosomes, where it can survive and multiply.

"Its ability to survive in amoeba is a huge advantage to its continued development as it may be more resistant to disinfectants and water treatment. This means that we need to work to understand ways of controlling amoeba in water supplied to animals and prevent it acting as a 'Trojan Horse' for Salmonella and other pathogens."


'/>"/>

Contact: Samantha Martin
samantha.martin@liv.ac.uk
44-151-794-2248
University of Liverpool
Source:Eurekalert

Related medicine news :

1. Penn study finds pro-death proteins required to regulate healthy immune function
2. New study shows promise in reducing surgical risks associated with surgical bleeding
3. Study, meta-analysis examine factors associated with death from heatstroke
4. Study suggests loss of 2 types of neurons -- not just 1 -- triggers Parkinsons symptoms
5. Study says COPD testing is not measuring up
6. Preclinical study suggests organ-transplant drug may aid in lupus fight
7. Ability to cope with stress can increase good cholesterol in older white men, study finds
8. High alcohol consumption increases stroke risk, Tulane study says
9. Mailman School of Public Health study examines link between racial discrimination and substance use
10. Pitt study finds inequality in tobacco advertising
11. Stanford study highlights cost-effective method of lowering heart disease risks
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:5/3/2016)... ... May 03, 2016 , ... Branches, Inc. is proud to ... Climb children and youth programs in South Miami. Macy’s is a wonderful community partner ... Grow Program provides afterschool tutoring, mentoring, enrichment and academic support to elementary students 5 ...
(Date:5/3/2016)... ... May 03, 2016 , ... Hydra Skin Sciences, a ... its Allegro Anti-aging Cream, a revolutionary new anti-aging skin care product that ... repair damaged skin, has sold over seventy-five thousand units worldwide within the first two ...
(Date:5/3/2016)... WA (PRWEB) , ... May 03, 2016 , ... Dave ... Pediatric Interim Care Center (PICC) annual fundraiser luncheon on Friday, May 20. ... that helps the smallest victims of drug abuse,” said Newberry. , PICC is a ...
(Date:5/2/2016)... , ... May 03, 2016 , ... ... its FDA approved sSOIP telemedicine stethoscope software that enables the stethoscope stream to ... called PCP-SSP and works with RNK’s flagship PCP-USB stethoscope. , Remote auscultation involves ...
(Date:5/2/2016)... ... May 02, 2016 , ... ProElectric Cartoon is a package of 30 ... choose from a variety of electric styles including zap, sizzles, and more. Easily alter ... dof blur, three dimensional rotation, and much more. ProElectric Cartoon’s simplistic style makes it ...
Breaking Medicine News(10 mins):
(Date:4/29/2016)... India , April 29, 2016 ... Pipeline Review, H1 2016" market research report that ... complete with comparative analysis at various stages, therapeutics ... route of administration (RoA) and molecule type, along ... releases. It also reviews key players involved in ...
(Date:4/29/2016)... April 29, 2016 Glycotope GmbH, ... today announces the appointment of Dr. Alfredo Zurlo ... is an oncologist with many years clinical experience and ... industries. His last role was at Mologen AG where ... Executive Board. Previously Dr. Zurlo held various positions at ...
(Date:4/28/2016)... , April 28, 2016  While Abbott,s ... complement the company,s valve repair and stent business, ... also places Abbott more firmly into patient monitoring.  ... the fastest growing device areas, with double-digit growth ... recent report,  Advanced Remote Patient Monitoring ...
Breaking Medicine Technology: