Navigation Links
Study shows how Salmonella survives in environment
Date:3/23/2009

Scientists at the University of Liverpool have demonstrated how a single-celled organism, living freely in the environment, could be a source of Salmonella transmission to animals and humans.

Salmonella are microscopic living creatures that can contaminate almost any food type, causing diarrhoea, abdominal pain and fever. Scientists know that Salmonella which can also cause typhoid fever has evolved unique mechanisms to prevent the body's immune system from functioning effectively, but until now it was not understood how it survives so successfully in the environment.

Scientists at Liverpool, in collaboration with the Institute for Animal Health, have shown that Salmonella use a secretion system to protect themselves inside amoeba a single-celled organism living on land and in the water. The research suggests that amoeba may be a major source of Salmonella within the environment and could play a significant role in transmission of infection to man and animals.

Salmonella uses a system, called SP12 type III, which acts as a bacterial machine inside organisms and causes disease in humans, animals and plants. The system employs a 'syringe-like' mechanism to inject bacteria into cells that would normally release compounds to rid the body of harmful substances. This system changes the structure of the cell and prevents these compounds from coming into contact with pathogens and destroying them.

Dr Paul Wigley, from the National Centre for Zoonosis Research, based at the University's Leahurst campus, explains: "Salmonella has managed to survive extremely successfully in the environment, finding its way into our food and causing illness, despite the body's best efforts to fight it off. We found that it uses a system which operates in the human immune system as well as inside amoeba living in the environment. This system essentially protects Salmonella within cellular compartments, called phagosomes, where it can survive and multiply.

"Its ability to survive in amoeba is a huge advantage to its continued development as it may be more resistant to disinfectants and water treatment. This means that we need to work to understand ways of controlling amoeba in water supplied to animals and prevent it acting as a 'Trojan Horse' for Salmonella and other pathogens."


'/>"/>

Contact: Samantha Martin
samantha.martin@liv.ac.uk
44-151-794-2248
University of Liverpool
Source:Eurekalert

Related medicine news :

1. Penn study finds pro-death proteins required to regulate healthy immune function
2. New study shows promise in reducing surgical risks associated with surgical bleeding
3. Study, meta-analysis examine factors associated with death from heatstroke
4. Study suggests loss of 2 types of neurons -- not just 1 -- triggers Parkinsons symptoms
5. Study says COPD testing is not measuring up
6. Preclinical study suggests organ-transplant drug may aid in lupus fight
7. Ability to cope with stress can increase good cholesterol in older white men, study finds
8. High alcohol consumption increases stroke risk, Tulane study says
9. Mailman School of Public Health study examines link between racial discrimination and substance use
10. Pitt study finds inequality in tobacco advertising
11. Stanford study highlights cost-effective method of lowering heart disease risks
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:2/22/2017)... Dallas, TX (PRWEB) , ... ... ... HCC Risk Adjustment solution leverages advanced data analytics to accurately understand each ... ensure proper reimbursement for a given population. This new solution helps transform ...
(Date:2/22/2017)... ... February 22, 2017 , ... Sideline Products participated in the World ... TV host Tom Seay and his production crew. Tom Seay’s program “Best of ... the world. Saddle Sidekicks will be featured on April 6, 2017. After the ...
(Date:2/22/2017)... ... February 22, 2017 , ... ANGLESTRONG , the new recovery management app ... the App Store and Google Play . Florida-based Sober Network, Inc., ... recovery industry, partnered with Angle to build ANGLESTRONG. The new recovery management app is ...
(Date:2/22/2017)... ... ... A product of digesting a micronutrient found in soy may hold the key ... while others do not, a University of Pittsburgh Graduate School of Public Health-led study ... some types of “good” gut bacteria when they metabolize isoflavones (micronutrients found in dietary ...
(Date:2/22/2017)... ... 22, 2017 , ... Super-Sod will attend the Athens Home Show with a ... A shift from Super-Sod’s simple Athens Home Show booth of 2016, this year’s exhibit ... plant manager Chris Roquemore constructed furniture from recycled pallet wood at the Super-Sod farm ...
Breaking Medicine News(10 mins):
(Date:2/23/2017)... Summary Provides understanding and ... agreements entered into by the worlds leading healthcare ... Description The Global Non-Hodgkin Lymphoma Partnering ... and access to partnering deals and agreements entered ... - Trends in partnering deals - ...
(Date:2/22/2017)... 22, 2017  Andre, DiMino, CEO of ADM Tronics ... of innovative technologies and products, commented on ADMT,s third ... 21, 2017 in the Company,s quarterly report on Form ... CEO Andre, DiMino stated "During the quarter ended December ... devoting a larger portion of our engineering efforts into ...
(Date:2/22/2017)... 22, 2017 Summary Provides ... deals and agreements entered into by the worlds ... http://www.reportlinker.com/p03605670-summary/view-report.html Description The Global Myocardial ... access to partnering deals and agreements entered into ... - Trends in partnering deals - Top ...
Breaking Medicine Technology: