Navigation Links
Study shows drug combination improves outcome for advanced non-small cell lung cancer
Date:5/30/2009

A new, international study found that the combination of two drugs delays disease progression for patients with advanced non-small cell lung cancer (NSCLC). Results from the Phase III "ATLAS" trial were presented today by Dr. Vincent Miller of Memorial Sloan-Kettering Cancer Center (MSKCC) at the American Society of Clinical Oncology Annual Meeting.

The goal of the study was to determine whether adding erlotinib (Tarceva), a targeted agent, to maintenance therapy with bevacizumab (Avastin), an agent commonly used as a component of treatment for advanced NSCLC would delay disease progression. Maintenance therapy involves using one or more agents of a chemotherapy regimen, but not the entire regimen, to delay disease progression and possibly improve survival after patients have previously received stronger standard chemotherapy, which can have significant side effects.

"This is the first study to show the addition of erlotinib to maintenance therapy prolongs progression-free survival in patients with advanced non-small cell lung cancer," said Dr. Miller, a thoracic oncologist at MSKCC and one of the study's lead authors. "Knowing which patients will get the greatest benefit from this combination, based on the identification of biomarkers, will be an important next step in this research," Dr. Miller added.

In total, 768 patients were randomized to receive bevacizumab plus erlotinib or bevacizumab plus placebo after initial cytotoxic chemotherapy with bevacizumab. There was a 29 percent reduction in the risk of progression for those patients treated with erlotinib, and the median progression-free survival (the time it took for the cancer to get worse) was 4.8 months for the combination versus 3.7 months for the bevacizumab-placebo group. Because a statistically significant improvement in efficacy was found in the erlotinib group, the trial was stopped early. The combination was also found to be safe and well tolerated.

Bevaciz
'/>"/>

Contact: Courtney DeNicola
denicolc@mskcc.org
212-639-3573
Memorial Sloan-Kettering Cancer Center
Source:Eurekalert

Page: 1 2

Related medicine news :

1. Penn study finds pro-death proteins required to regulate healthy immune function
2. New study shows promise in reducing surgical risks associated with surgical bleeding
3. Study, meta-analysis examine factors associated with death from heatstroke
4. Study suggests loss of 2 types of neurons -- not just 1 -- triggers Parkinsons symptoms
5. Study says COPD testing is not measuring up
6. Preclinical study suggests organ-transplant drug may aid in lupus fight
7. Ability to cope with stress can increase good cholesterol in older white men, study finds
8. High alcohol consumption increases stroke risk, Tulane study says
9. Mailman School of Public Health study examines link between racial discrimination and substance use
10. Pitt study finds inequality in tobacco advertising
11. Stanford study highlights cost-effective method of lowering heart disease risks
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:9/20/2014)... September 21, 2014 Diabetes Protocol ... Pullman that is helping thousands of people learn how ... without shots, pills, or prescriptions has caught the attention ... “There are currently tens of millions of people in ... and Type 2 diabetes, and unfortunately, big pharma makes ...
(Date:9/20/2014)... The Villa Group announced today that ... San Lucas, Villa La Estancia and Villa del Arco, ... plans to welcome guests back to the properties by ... all members and guests of the Villa Group’s Los ... effort with government authorities. , Hurricane Odile struck ...
(Date:9/20/2014)... Ticket Down is a reputable source ... popular ticket exchange is offering their customer appreciation promo code ... next step in the entertainment business. The 21-year-old from Boca ... and entertainment business, but is closing in on “Pop Diva” ... album, will hit the road next year on the “Honeymoon ...
(Date:9/20/2014)... 20, 2014 Lifeinsurancequoteterm.net has released ... no medical exam life insurance plan provides for vulnerable ... family members should be a top priority for every ... insurance without taking medical examinations and visiting a doctor. ... medical examinations will provide coverage up to $300,000, but ...
(Date:9/20/2014)... Ticket Down is a reputable source for ... “Honeymoon Tour.” This well-known ticket exchange is offering their ... early 2015, fans will have a chance to see one ... Twenty-one-year-old Ariana Grande will hit the road in February 2015 ... cities across the United States and Canada. Grande, the singer ...
Breaking Medicine News(10 mins):Health News:Diabetes Protocol: Review Exposes Kenneth Pullman’s Breakthrough Discovery About Diabetes Management 2Health News:Villa Group Resorts in Cabo Largely Unharmed, Plan to Re-open Early October 2Health News:Ariana Grande Tickets in Chicago/Rosemont, Kansas City, Milwaukee, Saint Paul, Dallas, Houston, San Antonio, Oklahoma City Go On Sale Today 2Health News:Ariana Grande Tickets in Chicago/Rosemont, Kansas City, Milwaukee, Saint Paul, Dallas, Houston, San Antonio, Oklahoma City Go On Sale Today 3Health News:No Medical Exam Life Insurance Provides Financial Protection for Families 2Health News:Ariana Grande Tickets in New York, Philadelphia, Orlando, Fairfax, Worcester, Toronto, Uncasville, Detroit, Miami, Pittsburgh, Cleveland, and Atlanta On Sale Today 2Health News:Ariana Grande Tickets in New York, Philadelphia, Orlando, Fairfax, Worcester, Toronto, Uncasville, Detroit, Miami, Pittsburgh, Cleveland, and Atlanta On Sale Today 3
... , , NEW YORK, Dec. 21 ... announce that its director, Diane E. Meier, MD , a ... HELP Committee. , As one of four 2009-2010 Health and ... directly participate in the policymaking process at the Federal level. The ...
... , ADA, Mich., Dec. 21 Amway Global and Disson Skating ... to air on NBC. Amway Global Improv-Ice is a special competition ... figure skating superstars by having them skate on the fly to ... and with that will come great entertainment for viewers to enjoy ...
... , AVENTURA, Fla., Dec. 21 Cinergy Health ... for the consumer market, expressed its concern for the ongoing healthcare ... , "While the Senate and House healthcare bills are far from ... expanding access to affordable health coverage for all Americans," said ...
... levels that could cause hearing loss , MONDAY, Dec. 21 ... or other music player this holiday season, consider a bonus ... to one-half or two-thirds of the actual maximum. , That,s ... warn that sound over 85 decibels -- well short of ...
... ... Longevity? , ... December 21, 2009 -- Medical breakthroughs and technological advances – in combination with healthy ... Mather LifeWays Institute on Aging . These and other positive trends will have ...
... RATON, Fla., Dec. 21 Flipping for Phonics(TM), the proven ... adults, has teamed up with Fisher House® to donate Flipping ... of $10,000 - to the children of military families at ... to make the holidays a bit brighter, children currently residing ...
Cached Medicine News:Health News:Center to Advance Palliative Care Director and MacArthur Recipient, Diane E. Meier, MD, Accepts Fellowship Post With Senate HELP Committee 2Health News:Amway Global Improv-Ice Provides Christmas Day Entertainment 2Health News:Amway Global Improv-Ice Provides Christmas Day Entertainment 3Health News:Cinergy Health Commentary on Senate Healthcare Vote 2Health News:Aging Institute Reveals 2010 Trends 2Health News:Aging Institute Reveals 2010 Trends 3Health News:Flipping for Phonics(TM) Helps Spread Cheer To Military Families In Fisher Houses(R) This Holiday Season 2Health News:Flipping for Phonics(TM) Helps Spread Cheer To Military Families In Fisher Houses(R) This Holiday Season 3
(Date:9/19/2014)... , September 19, 2014 ... has announced the addition of the ... to their offering.      (Logo: ... been broadly classified into wide categories based ... for the treatment of different gynecological conditions ...
(Date:9/19/2014)...  4WEB Medical announces the formal launch of the ... implants on the market today at this weekend,s ... Chicago .  The Osteotomy Truss System is ... with 74 size options included in one versatile set. ... 15 to 18 implant sizes, which limited a surgeon,s ...
(Date:9/19/2014)... 19, 2014 UBM Medica US announces that  ... community to help oncologists and other clinicians gain a ... use of targeted therapies and immunotherapies, discusses some of ... Every September, Blood Cancer Awareness ... awareness about blood cancers—helping to increase survival rates and ...
Breaking Medicine Technology:Global Gynecological Devices Market 2014-2018: Key Vendors are Bayer, Boston Scientific, CooperSurgical, Ethicon, Hologic, Medtronic, Olympus and Stryker 2Global Gynecological Devices Market 2014-2018: Key Vendors are Bayer, Boston Scientific, CooperSurgical, Ethicon, Hologic, Medtronic, Olympus and Stryker 34WEB Medical Unveils 3D-Printed Osteotomy Truss System 2OncoTherapy Network Highlights National Blood Cancer Awareness Month 2OncoTherapy Network Highlights National Blood Cancer Awareness Month 3OncoTherapy Network Highlights National Blood Cancer Awareness Month 4
... 2011 /PRNewswire-Asia-FirstCall/ -- Dehaier Medical Systems Ltd. (Nasdaq: ... leader in the development, assembly, marketing and sale of ... announced that Xiaoqing Wang, Ph.D., has been appointed Chief ... will report to Chief Executive Officer Mr. Chen Ping, ...
... (OTCBB: IAGX) issued today a shareholders, letter discussing the results of ... the future. Dear Imagenetix shareholder - ... and as we commence the new fiscal year, I would like ... the future.   Over the past few years our ...
Cached Medicine Technology:Dehaier Medical Systems Names Dr. Xiaoqing Wang New Chief Technology Officer 2Dehaier Medical Systems Names Dr. Xiaoqing Wang New Chief Technology Officer 3Imagenetix, Inc. Discusses March 31, 2011 Fiscal Year End Results and Future Focus 2Imagenetix, Inc. Discusses March 31, 2011 Fiscal Year End Results and Future Focus 3
The D.O.R.C. CryoStar is the smart cryosurgical system that combines optimal performance with state-of-the-art automation. simple for O.R. staff to operate and maintain throughout every procedure....
Eftiar® offers the vitreoretinal surgeon a temporary tamponade for efficient re-attachment of the retina, release of subretinal fluid, dissection of fibro-vascular proliferation and controlling r...
Red Rubber Robinson Catheters (Latex)...
Silver Foley Catheter 3-way...
Medicine Products: