Navigation Links
Study shows combination stroke therapy safe and effective
Date:7/30/2013

Health

Says Pancioli: "We know that the combination of these two medications dissolves clots faster and more completely than tPA alone. Our goal is to determine if we can use this combination to improve the outcomes for acute stroke victims."

CLEAR-ER investigators enrolled 126 subjects from July 2009 to October 2012. Of those, 101 received tPA plus eptifibatide and 25 received tPA alone. As the trial was a double-blind, randomized study, neither patient nor doctor was aware if the substance administered in addition to tPA was a medication or a placebo.

Investigators examined safety at specified endpoints, watching for incidence of intracerebral hemorrhage (ICH), and 90-day outcomes using a standardized measurement tool. Of the subjects who were given tPA plus eptifibatide, 50 (49.5 percent) had what were classified as good outcomes. Those who received tPA alone had nine good outcomes (36 percent).

Safety between the two groups was shown to be comparable at 36-hour, seven-day and 90-day endpoints.

The potential next step in investigation of the enhanced regimen, a phase-3 clinical trial, would typically use a larger pool of subjects determined by data from the phase-2 trial. Phase-3 trials, the last step before marketing of a medication, typically confirm its effectiveness, monitor side effects, compare it to commonly used treatments and collect information that will allow it to be used safely.


'/>"/>

Contact: Kathryn Cosse
kathryn.cosse@uc.edu
513-558-0207
University of Cincinnati Academic Health Center
Source:Eurekalert

Page: 1 2

Related medicine news :

1. Study Suggests Vaccine May Help Kids With Brain Cancer
2. Study reveals how cancer drug causes diabetic-like state
3. Coffee Drinking in Pregnancy Wont Lead to Sleepless Baby: Study
4. Lower GI problems plague many with rheumatoid arthritis, Mayo Clinic study finds
5. Veggies Like Broccoli, Cabbage May Help Fight Breast Cancer: Study
6. No Added Cancer Risk From Hip Replacement Materials: Study
7. Reported Decline in U.S. Pneumonia Deaths May Be False: Study
8. Early Study Finds Some Promise for Lung Cancer Vaccine
9. Narcissists Often Ace Job Interviews, Study Finds
10. Sexual objectification of female artists in music videos exists regardless of race, MU study finds
11. Soy may alleviate hot flashes in menopause, large-scale study finds
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:10/31/2014)... City, UT (PRWEB) October 31, 2014 ... the new Activz Silver line offering natural ... cleansing wipes. For over a century, silver has been ... found in Activz Silver products is the most advanced ... patents, has a unique chemical structure that supports the ...
(Date:10/31/2014)... Oct. 31, 2014 (HealthDay News) -- Obesity increases the ... black and Hispanic women, two new U.S. studies show. ... found being overweight or obese increased the risk for ... women. "We,ve known this for a long time ... also in Hispanic women," study author Esther John, a ...
(Date:10/31/2014)... Johns Hopkins engineers have invented a lab device to ... the complex way that tumor cells spread through the ... By shedding light on precisely how tumor cells travel, ... in check. , The inventors, from the university,s Whiting ... published details and images from their new system recently ...
(Date:10/31/2014)... Miami Beach, Florida (PRWEB) October 31, 2014 ... Hydroponics” or, the “Company”) today announced it has signed ... three Canada-based companies in the urban cultivation sector - ... Ltd. (BC Northern Lights”), and W3 Metal Inc. (“W3 ... Lights, the “Target Companies”). Pursuant to the LOI ...
(Date:10/31/2014)... NY (PRWEB) October 31, 2014 In an ... York patients, Dr. Majid Jamali announced he will soon offer ... practice by the end of November. , To build ... Maxillofacial Surgery of New York has become known for, Dr. ... boasts degrees from such top learning institutions as UCLA, Stanford ...
Breaking Medicine News(10 mins):Health News:New Collection of Nano-particle Natural Silver Products by Activz Whole-Food Nutrition 2Health News:New Collection of Nano-particle Natural Silver Products by Activz Whole-Food Nutrition 3Health News:New Collection of Nano-particle Natural Silver Products by Activz Whole-Food Nutrition 4Health News:Study Confirms Obesity-Breast Cancer Link for Blacks, Hispanics 2Health News:Viewing cancer on the move: New device yields close-up look at metastasis 2Health News:Viewing cancer on the move: New device yields close-up look at metastasis 3Health News:Urban Hydroponics Inc. Signs Definitive Agreement to Merge with Canadian Hydroponics Companies 2Health News:Urban Hydroponics Inc. Signs Definitive Agreement to Merge with Canadian Hydroponics Companies 3Health News:Urban Hydroponics Inc. Signs Definitive Agreement to Merge with Canadian Hydroponics Companies 4Health News:Urban Hydroponics Inc. Signs Definitive Agreement to Merge with Canadian Hydroponics Companies 5Health News:Oral & Maxillofacial Surgery of New York Adds Orthodontic Patient Services 2Health News:Oral & Maxillofacial Surgery of New York Adds Orthodontic Patient Services 3
... rival many developed countriesSEATTLE, March 19 ... developing nations, access to healthcare, today announced significant ... strengthening program in Mozambique. The results of ... that rival those of many developed countries. VillageReach ...
... the actress, sudden death, doctors say , , THURSDAY, March ... on Natasha Richardson expected later Thursday, many are wondering ... after a seemingly minor fall on a beginner,s ski ... examiner was performing the autopsy. The 45-year-old Richardson reportedly ...
... U.S. Representative Gerry Connolly, several prominent doctors from ... held a press conference today to call for quick ... Food and Drug Administration (FDA) authority over tobacco products. ... bill earlier this month and a full House vote ...
... the Centre for Addiction and Mental Health (CAMH) and ... greatest risk factor for acetaldehyde-related cancer. Heavy drinkers ... multiple sources. , Acetaldehyde is ubiquitous in daily life ... is inhaled from the air and tobacco smoke, ingested ...
... International Symposium April 1-5, 2009 at Marriott ... The National Osteoporosis Foundation (NOF) will bring ... share clinically relevant evidence-based information on bone ... with hundreds of healthcare professionals at its ...
... local business, labor, academic and health care groups, ... House of Delegates Health & Government Operations Committee, ... -- a unique network of partners dedicated to ... the United States and in Maryland. "New advancements ...
Cached Medicine News:Health News:VillageReach Announces Results of Five-Year Health System Improvement Program in Mozambique 2Health News:NYC Medical Examiner Peforming Autopsy on Natasha Richardson 2Health News:NYC Medical Examiner Peforming Autopsy on Natasha Richardson 3Health News:U.S. Rep. Connolly, Inova Health System Physicians, Public Health Groups Call for Congressional Action to Protect Kids from Tobacco 2Health News:U.S. Rep. Connolly, Inova Health System Physicians, Public Health Groups Call for Congressional Action to Protect Kids from Tobacco 3Health News:U.S. Rep. Connolly, Inova Health System Physicians, Public Health Groups Call for Congressional Action to Protect Kids from Tobacco 4Health News:Acetaldehyde in alcohol -- no longer just the chemical that causes a hangover 2Health News:Latest Osteoporosis Research Translated for Health Professionals to Use in Clinical Setting 2Health News:Maryland 'We Work for Health' Calls on Elected Officials to Focus on Medical Research and Innovation to Bolster Economy and Find Cures 2Health News:Maryland 'We Work for Health' Calls on Elected Officials to Focus on Medical Research and Innovation to Bolster Economy and Find Cures 3
(Date:10/30/2014)... , Oct. 30, 2014  Zimmer Holdings, Inc. (NYSE: ... the future executive leadership team and organizational structure of ... transaction.  Zimmer also announced that the combined organization will ... be named Zimmer Biomet, with the new brand to ... closing of the merger.  The future leadership team is ...
(Date:10/30/2014)... VIEW, Calif. , Oct. 30, 2014 /PRNewswire/ ... accelerated dramatically as a result of government initiatives ... time - healthcare providers have invested over the ... the heart of health IT, and U.S. clinicians ... Logo - http://photos.prnewswire.com/prnh/20141029/155278LOGO ...
(Date:10/30/2014)... NEW YORK , Oct. 30, 2014  The ... United States is growing steadily, thanks to ... years, as a result of the economic downturn, retail ... was a year of opportunities, as the number of ... market researcher,s report, Retail Clinics Market Overview and ...
Breaking Medicine Technology:Zimmer Announces Executive Leadership Team and New Name of Combined Company Following Closing 2Zimmer Announces Executive Leadership Team and New Name of Combined Company Following Closing 3Zimmer Announces Executive Leadership Team and New Name of Combined Company Following Closing 4Zimmer Announces Executive Leadership Team and New Name of Combined Company Following Closing 5Zimmer Announces Executive Leadership Team and New Name of Combined Company Following Closing 6Zimmer Announces Executive Leadership Team and New Name of Combined Company Following Closing 7Zimmer Announces Executive Leadership Team and New Name of Combined Company Following Closing 8Zimmer Announces Executive Leadership Team and New Name of Combined Company Following Closing 9Electronic Health Record Usability: CIOs Weigh In 2Electronic Health Record Usability: CIOs Weigh In 3Electronic Health Record Usability: CIOs Weigh In 4Report: Drugstore Chains Drive Retail Clinic Growth 2Report: Drugstore Chains Drive Retail Clinic Growth 3
... fume containment system is ... equipment. Even large benchtop ... the Hyperclean 2. The ... unit comes complete with one ...
Reusable shielded cable...
... OIA test features a dual-detection technology to ... for children under age 5 with a ... in just over 15 minutes. This combination ... to decrease costs for unnecessary ancillary testing, ...
... OIA A/B test combines performance equivalence to 14-day ... A or B with a simple, easy-to-use test ... test has all the same procedural steps as ... enable you decrease costs for unnecessary ancillary testing, ...
Medicine Products: