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Study shows additional role for abiraterone in blocking tumor growth in CRPC
Date:3/15/2013

RPC," added Moll.

Moll also said that "it is clear that the AR remains the most important target in the treatment of CRPC."

"Blockade of androgen synthesis seems not sufficient to prevent AR activation. New drugs that block AR activation irrespective of the activating ligand may provide new ammunition to last another 'round' for clinicians to treat CRPC," he said. "We believe it is vital to identify which metabolites have the potential to activate the mutated or overexpressed AR present in CRPC, which under normal conditions may not activate the AR. In that perspective, we are currently working together with our partner, Janssen, and other partners within the IMI-PREDECT consortium on developing new model systems for CRPC to further understand its biology and test new potential pathway perturbations that may benefit CRPC patients in the future."


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Contact: Ivanka Moerkerken
i.moerkerken@uroweb.org
31-026-389-0680
European Association of Urology
Source:Eurekalert

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