Navigation Links
Study shows SBRT for stage I NSCLC safe and effective
Date:7/1/2013

DENVER Stereotactic body radiotherapy (SBRT) is considered the treatment of choice for early-stage nonsmall-cell lung cancer (NSCLC) if patients are inoperable because of additional medical conditions. This is based on several prospective phase II trials, which reported consistently high rates of local tumor control. However, these studies only included small number of patients, the methodology of SBRT varied between the studies and SBRT was mainly practiced in specialized centers. Therefore, safety and efficacy of SBRT practiced in routine clinical practice outside of study protocols is not well analyzed.

A working group called Extracranial Stereotactic Radiotherapy was formed within the German Society for Radiation Oncology and this group performed a patterns-of-care and patterns-of-outcome analysis looking at safety and efficacy of SBRT for stage I NSCLC in Germany and Austria. Their research, published in the August issue of the Journal of Thoracic Oncology (JTO), concludes SBRT for stage I NSCLC was safe and effective in this multi-institutional environment. In addition, radiotherapy dosage was identified as a major treatment factor influencing local tumor control and overall survival.

The researchers looked at data from 582 patients treated at 13 institutions between 1998 and 2011. Average follow-up for all patients was 21.4 months and the maximum was 144 months (12 years); follow-up was more than 3 years for 108 patients. Three-year freedom from local progression was 79.6 percent for all 582 patients.

The biological effective dosage was the most significant factor influencing freedom from local progression and overall survival. No evidence of a learning curve or improvement of results with larger SBRT experience and implementation of new radiotherapy technologies was observed. The group concluded that SBRT for stage I NSCLC was safe and effective in this multi-institutional, academic environment, despite considerable inter-institutional variability and time trends in SBRT practice.


'/>"/>

Contact: Kristal Griffith
Kristal.Griffith@iaslc.org
720-325-2952
International Association for the Study of Lung Cancer
Source:Eurekalert

Related medicine news :

1. Study links cardiac hormone-related inflammatory pathway with tumor growth
2. How to boost Hispanics participation in clinical trials? Relate to them, Moffitt study shows
3. Impact of iPad® on radiology residents daily clinical duties is limited, study suggests
4. New study on popular prostate cancer protein provides insight into disease progression
5. Study finds dramatic increase in hospitalization of US children with inflammatory bowel disease
6. GAP-AF study helps to define optimal approach to ablation
7. New Study: Alcohol Drinkers May Face Long Term Health Issues
8. A Study Shows That Mom’s Obesity Surgery May Help Break Cycle in Obese Kids
9. New Study Casts Doubt on FDA Pradaxa Conclusions
10. Results of landmark 11-year study on weight losss effect on heart disease risks published today
11. Rottenstein Law Group LLP Acknowledges BMJ Study of Risks of Byetta, Januvia
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:1/23/2017)... ... , ... "ProRandom is a set of camera tools that allow video editors to integrate up ... X," said Christina Austin - CEO of Pixel Film Studios. , With ProRandom, video ... footage. ProRandom works by using a virtual camera to create the illusion of a ...
(Date:1/23/2017)... , ... January 23, 2017 , ... ... high-quality general gynecological care and gynecological services for women of all ... care for a wide variety of reproductive services from routine health screenings to ...
(Date:1/23/2017)... ... January 23, 2017 , ... The ... at seafoodnutrition.org/programs and seafoodnutrition.org/resources to assist in teaching communities and individuals about ... been developed for use by nutrition educators and influencers within the public ...
(Date:1/23/2017)... ... January 23, 2017 , ... Valentine’s Day is a time when many people celebrate ... For those who may be looking for the ideal present, Atlanta-based Perimeter Plastic Surgery ... an additional $25 free. Or, spend $200 and get $50 free. , “A lot ...
(Date:1/22/2017)... Viejo, California (PRWEB) , ... January 22, 2017 , ... ... Photo Cloud to create a beautiful 3D slideshow with complete ease," said Christina Austin ... the Generators browser to place in the FCPX timeline. Presets include scenes ...
Breaking Medicine News(10 mins):
(Date:1/23/2017)... , Jan 23, 2017 Research and Markets ... Analysis & Trends - Product - Forecast to 2025" report to ... Report Highlights: ... and future market trends to identify the investment opportunities ... Key market trends across the business segments, Regions and ...
(Date:1/23/2017)... -- Stock-Callers.com today presents the following Generic Drugs ... ), Sophiris Bio Inc. (NASDAQ: SPHS ), Momenta ... Inc. (NASDAQ: AGRX ). These companies are part ... trade on Friday, January 20 th , 2017, with the ... health care companies in the S&P 500 also were sinking ...
(Date:1/23/2017)... , 23. Januar 2017  ResMed (NYSE: ... ) und 3B Medical ( Winter Haven, Florida ... eine Vereinbarung über die Beilegung aller globalen Rechtsstreitigkeiten zwischen ... der Verkauf ihrer bestehenden Produkte im Tausch gegen ... Zahlung an 3B leisten, um das in ...
Breaking Medicine Technology: