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Study shows PRP, commonly used technique to improve healing, doesn't work in rotator cuff surgery
Date:2/18/2011

For years, doctors have used platelet rich plasma (PRP) to promote healing in various surgeries, but a recent study demonstrates that a type of PRP did not improve healing after rotator cuff repair. The study, conducted by Hospital for Special Surgery (HSS) investigators, will be presented at the upcoming American Orthopedic Society for Sports Medicine (AOSSM) 2011 Specialty Day meeting, held Feb. 19 in San Diego, Calif., following the annual meeting of the American Academy of Orthopaedic Surgeons.

"I would not recommend platelet-rich fibrin matrix [PRFM] as we used it in this study until we gain further information," said Scott Rodeo, M.D. He led the study and is co-chief of the Sports Medicine and Shoulder Service and professor of Orthopedic Surgery at HSS. PRP has been used extensively in orthopedic surgeries and the study begs the question of whether it has been used prematurely in some cases, before sufficient evidence has accumulated to back up its usefulness.

"The general PRP has been used extensively in orthopedics and in other areas," Dr. Rodeo said. "There are a number of different types of PRP, and I think we need more information to identify the appropriate doses and the appropriate timing of giving it."

For roughly 15 years, PRP has been used to improve healing in various surgeries, especially oral and maxillofacial surgery, with varying degrees of success. Because there is a rate of incomplete or failed healing after rotator cuff repair surgeries, investigators at HSS set out to test whether a type of PRP, platelet-rich fibrin matrix (PRFM), could improve tendon healing in this surgery.

Platelets have proteins that are known to improve cell proliferation, cell division, and cell migration, a myriad of processes that can encourage healing. To create PRP, doctors extract blood from a patient and then use a centrifuge to isolate the platelets. In the study presented at AOSSM, the investigators then used calcium c
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Contact: Phyllis Fisher
phyllis.fisher@gmail.com
212-606-1197
Hospital for Special Surgery
Source:Eurekalert

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