Navigation Links
Study showed oxaliplatin improved colon cancer patient survival
Date:1/20/2012

Stage III colon cancer patients in the general population who receive adjuvant treatment for the disease have an improved rate of survival when oxaliplatin is added to 5-fluorouracil (5FU), according to a study published Jan. 20 in the Journal of the National Cancer Institute.

Colon cancer is a leading global cause of both illness and death; with an estimated 101,340 cases among Americans in 2011. Roughly one third of diagnoses are stage III or node-positive disease. In randomized clinical trials (RCTs), adding oxaliplatin to adjuvant 5FU is known to improve outcomes of patients with stage III colon cancer. But the effect of this combined therapy outside RCTs is unknown. In addition, fewer than 2% of patients with the cancer enroll in RCTs, and participants are known to be generally younger, healthier and less racially diverse than the overall cancer patient population.

In order to determine the effects of combined therapy in stage III colon cancer patients in the general population, Hanna K. Sanoff M.D., and assistant professor of Medicine, Hematology and Oncology at the University of Virginia School of Medicine and colleagues, gathered data from patients using the Surveillance, Epidemiology, and End Results registry linked to Medicare claims (SEER-Medicare), among other cancer registries. All patients had stage III colon cancer, received chemotherapy within 120 days of surgery, and were age 75 years or younger. Overall survival (OS) was then compared between patients treated with combined therapy and standard chemotherapy.

The researchers found that adding oxaliplatin to adjuvant therapies for stage III colon cancer in patients of the general cancer population was just as effective as in patients from RCTs. The addition of oxaliplatin showed improved survival across various practice settings, including those with older and minority patients as well as patients with greater comorbidity. "Physicians and patients should be reas
'/>"/>

Contact: Zachary Rathner
Zachary.Rathner@oup.com
301-841-1286
Journal of the National Cancer Institute
Source:Eurekalert

Page: 1 2

Related medicine news :

1. Despite Treatment, Employees with Depression Generate Higher Absentee Costs, According to Thomson Reuters Study
2. American Council on Exercise (ACE) Study Reveals Kettlebells Provide Powerful Workout in Short Amount of Time
3. TV drama can be more persuasive than news program, study finds
4. Study carried out into biological risks of eating reptiles
5. Neuroimaging study may pave way for effective Alzheimers treatments
6. Study finds racial gaps continue in heart disease awareness
7. Luth Researchs IndicatorEDG(TM) Study Finds Americans Hopes of Achieving Their Dreams Are Fading
8. First blinded study of venous insufficiency prevalence in MS shows promising results
9. Soothing infants with food focus of childhood obesity study
10. People with anxiety disorder less able to regulate response to negative emotions, study shows
11. American Heart Association Rapid Access Journal Report: Study Finds Racial Gaps Continue in Heart Disease Awareness, Low Knowledge of Heart Attack Warning Signs Among Women
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:11/23/2014)... Locks-Magnetic.com, a notable magnetic locks maker, has released a ... are available at low rates up to 30% off. ... new emergency doors. The emergency door adopts fireproof material ... several colors. All of the products are top-quality guaranteed. ... not as easy as many people think. As ...
(Date:11/23/2014)... (PRWEB) November 23, 2014 More than ... month in a federal litigation involving Byetta lawsuits ( ... medications, Bernstein Liebhard LLP reports. , A Case ... over a class of Type 2 diabetes medications referred ... the U.S. District Court, Southern District of California, where ...
(Date:11/23/2014)... Falls Church, VA (PRWEB) November 23, 2014 ... and TV Have in Common, **FDAnews On-Demand Webinar**, Dec. ... http://www.fdanews.com/TheFDAisWatchingOnDemand , The FDA’s focus on promotional ... ads. , Now they're looking at websites, ... , Mark the calendar for Thursday, Dec. 11, for ...
(Date:11/23/2014)... 23, 2014 Today Zane Benefits, ... small businesses, announced their new on demand webinar ... Employer-Provided Health Insurance. , According to ... financial risk facing most American families. It is ... and large, when it comes to recruiting and ...
(Date:11/22/2014)... PrettyTailor , an outstanding dress company, ... promotion. Customers can buy new dresses at its online ... its website. , As a matter of fact, PrettyTailor ... mainly provides four types of wedding outfits, including bridesmaid ... dresses. It also provides a variety of occasion dresses, ...
Breaking Medicine News(10 mins):Health News:California Federal Court Overseeing Byetta Lawsuits, Other Incretin Mimetic Claims Adds New Cases in November, Bernstein Liebhard LLP Reports 2Health News:California Federal Court Overseeing Byetta Lawsuits, Other Incretin Mimetic Claims Adds New Cases in November, Bernstein Liebhard LLP Reports 3Health News:California Federal Court Overseeing Byetta Lawsuits, Other Incretin Mimetic Claims Adds New Cases in November, Bernstein Liebhard LLP Reports 4Health News:FDAnews Announces The FDA is Watching: What Twitter, Tradeshows and TV Have in Common, On-Demand Webinar, Dec. 11, 2014 2Health News:FDAnews Announces The FDA is Watching: What Twitter, Tradeshows and TV Have in Common, On-Demand Webinar, Dec. 11, 2014 3Health News:FDAnews Announces The FDA is Watching: What Twitter, Tradeshows and TV Have in Common, On-Demand Webinar, Dec. 11, 2014 4Health News:FDAnews Announces The FDA is Watching: What Twitter, Tradeshows and TV Have in Common, On-Demand Webinar, Dec. 11, 2014 5Health News:Zane Benefits, Inc. Announces New Webinar on The End of Employer-Provided Health Insurance Now Available On-Demand! 2Health News:Customers Are Welcome to Shop at PrettyTailor.com 2
... , , LAS VEGAS, July ... that its Board of Directors has approved $50,000 in contributions to ... and $50,000 for The International Problem Gambling Center in Las Vegas. ... support of organizations dedicated to the issue of problem gambling. , ...
... , , NORFOLK, Va., July 27 ... Va., has won a contract to provide administrative services for ... , (Logo: http://www.newscom.com/cgi-bin/prnh/20090106/PH55551LOGO ... has set up a service center in Linthicum, where 51 ...
... , , , ... Solutions Alliance today announced Kiwok Nordic AB as the winner ... Awards. Judges selected Kiwok for its BodyKom Series remote ECG ... allows heart patients to live independently while their heart is ...
... , , WILLOW ... affected by HIV/AIDS and poverty just hours before they were scheduled ... cancelled. The session, part of the organization,s Camp Heartland program, was ... commonly known as the Swine Flu. , , ...
... July 27 Quark Pharmaceuticals, Inc., a development-stage pharmaceutical ... today announced data suggesting that QPI-1007 prevents progressive retinal ... (IOP) rat model of glaucoma. The experiments performed by ... and Cell Biology, Universite de Montreal, indicate that QPI-1007 ...
... , , , ... (OTC Bulletin Board: ACCP) announced today that its ... MuGard in Norway. This follows previous commercial launches ... Pharmaceuticals, SpePharm is responsible for manufacturing, regulatory approval and commercialization in the ...
Cached Medicine News:Health News:Association of Gaming Equipment Manufacturers (AGEM) Announces $100,000 in Contributions to Organizations Working to Assist Problem Gamblers 2Health News:Association of Gaming Equipment Manufacturers (AGEM) Announces $100,000 in Contributions to Organizations Working to Assist Problem Gamblers 3Health News:ValueOptions Wins Maryland Mental Health Contract 2Health News:Itanium Solutions Alliance Selects Sweden's Kiwok as the 2009 Innovation Awards Winner for Humanitarian Impact 2Health News:Itanium Solutions Alliance Selects Sweden's Kiwok as the 2009 Innovation Awards Winner for Humanitarian Impact 3Health News:Itanium Solutions Alliance Selects Sweden's Kiwok as the 2009 Innovation Awards Winner for Humanitarian Impact 4Health News:Itanium Solutions Alliance Selects Sweden's Kiwok as the 2009 Innovation Awards Winner for Humanitarian Impact 5Health News:Itanium Solutions Alliance Selects Sweden's Kiwok as the 2009 Innovation Awards Winner for Humanitarian Impact 6Health News:H1N1 'Swine Flu' Leads to Cancellation of HIV/AIDS Summer Camp. One Heartland Announces Campaign to Fund Alternative Camp Session for 82 Children. 2Health News:Quark Pharmaceuticals Announces Data Indicating Potential Utility of QPI-1007 for Treatment of Glaucoma 2Health News:Quark Pharmaceuticals Announces Data Indicating Potential Utility of QPI-1007 for Treatment of Glaucoma 3Health News:Access Pharmaceuticals Announces Commercial Launch of MuGard(TM) in Norway by SpePharm 2Health News:Access Pharmaceuticals Announces Commercial Launch of MuGard(TM) in Norway by SpePharm 3Health News:Access Pharmaceuticals Announces Commercial Launch of MuGard(TM) in Norway by SpePharm 4
(Date:11/22/2014)... HILL, N.C. , Nov. 21, 2014 /PRNewswire/ ... healthcare system. Undoubtedly, the growing influence of patients ... spend for marketing interactions. Now, more than ever, ... retain patients for medical products is essential. ... firm, Best Practices, LLC, benchmarked companies spent about ...
(Date:11/21/2014)... , Nov. 21, 2014  Tandem Diabetes ... ), a medical device company and manufacturer of ... a partnership with Tidepool, a non-profit dedicated to ... source software platform that increases diabetes data accessibility. ... Platform, which is currently under development, to download ...
(Date:11/21/2014)... Ill. , Nov. 21, 2014  Heated dialogue ... drug prices – from cancer treatments to Gilead,s new ... pharmaceutical leaders around the world questioning what it means ... of care. And while drug pricing ... pharmaceutical industry – from both a general business and ...
Breaking Medicine Technology:New Report Details Importance of Adopting a "Patient Journey" Framework in Marketing 2Tandem Diabetes Care Announces Partnership with Tidepool to Further Expand Access to Diabetes Device Data 2Tandem Diabetes Care Announces Partnership with Tidepool to Further Expand Access to Diabetes Device Data 3"The Price of Global Health" Tackles Worldwide Drug-Pricing Debate 2"The Price of Global Health" Tackles Worldwide Drug-Pricing Debate 3"The Price of Global Health" Tackles Worldwide Drug-Pricing Debate 4"The Price of Global Health" Tackles Worldwide Drug-Pricing Debate 5
... and SOUTH SAN FRANCISCO, May 18, 2011 Bayer HealthCare ... ) today announced that data evaluating the use of Nexavar® ... the 2011 Annual Meeting of the American Society of Clinical ... and Onyx remain committed to researching the potential utility of ...
... JOSE, Calif., May 18, 2011 Oclaro, Inc. ... of optical communications and laser solutions, today outlined its ... technology direction of future products.  As a leading provider ... able to leverage its world-class manufacturing operations, technology expertise ...
Cached Medicine Technology:Nexavar Data to Be Presented at American Society of Clinical Oncology Annual Meeting 2Nexavar Data to Be Presented at American Society of Clinical Oncology Annual Meeting 3Nexavar Data to Be Presented at American Society of Clinical Oncology Annual Meeting 4Nexavar Data to Be Presented at American Society of Clinical Oncology Annual Meeting 5Nexavar Data to Be Presented at American Society of Clinical Oncology Annual Meeting 6Nexavar Data to Be Presented at American Society of Clinical Oncology Annual Meeting 7Oclaro Provides Complete Fiber Laser Diode Solutions Portfolio; Outlines Future Innovation and Technology Advancements 2Oclaro Provides Complete Fiber Laser Diode Solutions Portfolio; Outlines Future Innovation and Technology Advancements 3
Colloidal Gold Sol, 40 nm - 12 - 15, 1 ml, Gold Sol Nanoparticles - not boiled, not centrifuged...
... magnification all glass (1.5x) Gonio lens will ... ease., The 4 mirror lens is the ... dynamic gonioscopy and features : , ... appreciate details previously unattainable with Gonio lenses., ...
Colloidal Gold Sol, 20 nm - 50 OD, 1 ml, Gold Sol Nanoparticles - not boiled, not centrifuged...
... The PalmScan P2000 Pachymeter [i.e., PalmScan ... portable,battery operated biometer, which incorporates A-mode ... used to accurately measure the corneal ... human eyes. PalmScan P2000 includes two ...
Medicine Products: