Navigation Links
Study showed oxaliplatin improved colon cancer patient survival
Date:1/20/2012

Stage III colon cancer patients in the general population who receive adjuvant treatment for the disease have an improved rate of survival when oxaliplatin is added to 5-fluorouracil (5FU), according to a study published Jan. 20 in the Journal of the National Cancer Institute.

Colon cancer is a leading global cause of both illness and death; with an estimated 101,340 cases among Americans in 2011. Roughly one third of diagnoses are stage III or node-positive disease. In randomized clinical trials (RCTs), adding oxaliplatin to adjuvant 5FU is known to improve outcomes of patients with stage III colon cancer. But the effect of this combined therapy outside RCTs is unknown. In addition, fewer than 2% of patients with the cancer enroll in RCTs, and participants are known to be generally younger, healthier and less racially diverse than the overall cancer patient population.

In order to determine the effects of combined therapy in stage III colon cancer patients in the general population, Hanna K. Sanoff M.D., and assistant professor of Medicine, Hematology and Oncology at the University of Virginia School of Medicine and colleagues, gathered data from patients using the Surveillance, Epidemiology, and End Results registry linked to Medicare claims (SEER-Medicare), among other cancer registries. All patients had stage III colon cancer, received chemotherapy within 120 days of surgery, and were age 75 years or younger. Overall survival (OS) was then compared between patients treated with combined therapy and standard chemotherapy.

The researchers found that adding oxaliplatin to adjuvant therapies for stage III colon cancer in patients of the general cancer population was just as effective as in patients from RCTs. The addition of oxaliplatin showed improved survival across various practice settings, including those with older and minority patients as well as patients with greater comorbidity. "Physicians and patients should be reas
'/>"/>

Contact: Zachary Rathner
Zachary.Rathner@oup.com
301-841-1286
Journal of the National Cancer Institute
Source:Eurekalert

Page: 1 2

Related medicine news :

1. Despite Treatment, Employees with Depression Generate Higher Absentee Costs, According to Thomson Reuters Study
2. American Council on Exercise (ACE) Study Reveals Kettlebells Provide Powerful Workout in Short Amount of Time
3. TV drama can be more persuasive than news program, study finds
4. Study carried out into biological risks of eating reptiles
5. Neuroimaging study may pave way for effective Alzheimers treatments
6. Study finds racial gaps continue in heart disease awareness
7. Luth Researchs IndicatorEDG(TM) Study Finds Americans Hopes of Achieving Their Dreams Are Fading
8. First blinded study of venous insufficiency prevalence in MS shows promising results
9. Soothing infants with food focus of childhood obesity study
10. People with anxiety disorder less able to regulate response to negative emotions, study shows
11. American Heart Association Rapid Access Journal Report: Study Finds Racial Gaps Continue in Heart Disease Awareness, Low Knowledge of Heart Attack Warning Signs Among Women
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:7/14/2014)... Doctor Mike Hamilton from Inception Chiropractic ... company website. The Inception website is a place for ... It's also a place for potential clients to learn ... When contacted at his office, Doctor Hamilton said, "We're ... website. Our site is obviously a great place for ...
(Date:7/14/2014)... 2014 Love Digits LLC has successfully ... Digits. The App brings ancient astrology to the modern ... their compatibility using a five-star rating system. By entering ... instantaneously test their compatibility for love and marriage across ... app’s five-star rating system generates a weighted average of ...
(Date:7/14/2014)... Spine Team Texas continues to stay ... treatment and recovery. Currently all physical therapists at Spine ... for certification in The McKenzie Method. Two therapists, Craig ... program. , “We require certification of our therapists because ... outcomes for spine pain patients,” said Mark Hood, CEO ...
(Date:7/14/2014)... Townsend Security, a leading authority ... IBM i (AS/400, iSeries) Two Factor Authentication Partner ... threats evolve and make passwords ineffective for system ... their applications and implement two factor authentication (2FA). ... for ISVs on the IBM i platform to ...
(Date:7/14/2014)... Crystal Dental has recently announced that it will ... made via LAD Solutions in in order to increase awareness ... in order to draw in new patients that can now ... Dental offers a variety of services for both routine and ... include cosmetic dentistry procedures such as porcelain veneers and dental ...
Breaking Medicine News(10 mins):Health News:Doctor Mike Hamilton From Inception Chiropractic Websites Announces the Launch of Their New Website 2Health News:Love Digits, Numerical Approach to Modern Love, Now Available on iTunes 2Health News:Love Digits, Numerical Approach to Modern Love, Now Available on iTunes 3Health News:Spine Team Texas’ Physical Therapists Complete The McKenzie Method Training and Certification 2Health News:Spine Team Texas’ Physical Therapists Complete The McKenzie Method Training and Certification 3Health News:IBM i ISVs Can Now Easily Integrate Mobile-Based Two Factor Authentication to Increase Security of Solutions 2Health News:IBM i ISVs Can Now Easily Integrate Mobile-Based Two Factor Authentication to Increase Security of Solutions 3Health News:Crystal Dental Announces the Opening of New Office Location in Sacramento 2
... Centre and Kenya has been asked to spell out, account ... intended 134 million. The fund was provided to Kenya to ... have to provide the accounts of how the money was ... Kenya has been ridden with serious corruption problems that have ...
... The burden of HIV, malaria and Tuberculosis in most ... //The European Union, UNAIDS, WHO and the Indian Government ... the diseases. ,"These diseases mostly affect the ... aim to share our experiences and develop strategies to ...
... drug manufactured by German pharmaceutical company TeGenero by medical research ... designed to treat rheumatoid arthritis, leukaemia and multiple sclerosis was ... who fell seriously ill after taking part in a drug ... brain was on fire. Student Nav Modi, 24, said that ...
... an NGO official India’s population stabilization solely rests on ... which has the highest fertility rates. ,'India's population ... an immediate lead in checking population growth' A.R. Nanda, ... ,'If high growth states like Bihar and Uttar Pradesh, ...
... funds to the tune of ?4m or more will be ... This spending should take care of containing// the unhealthy trend, ... gone up by almost 50%. ,A senior medical ... problems with suicidal tendencies, according to Mr Woodward. To enable ...
... high risk of the potentially-fatal condition of pre-eclampsia, should ... Vitamin C and E. // Recent research has suggested that ... and can trigger pre-eclampsia. ,Pre-eclampsia, is a dangerous condition ... women which is a common cause of deaths and still ...
Cached Medicine News:
(Date:7/11/2014)... N.C. , July 11, 2014 ... approaches are evolving across industry sectors to better ... examining better ways to engage with and understand ... inform themselves and make critical purchasing decisions. ... firm, Best Practices, LLC, one area where organizations ...
(Date:7/11/2014)... Research and Markets has announced the addition ... Industry Report 2014" report to their offering. ... And Chinese Medical X-Ray Film Industry Report 2014 is ... of the Global medical X-ray film industry with a ... a basic overview of the industry including definitions, classifications, ...
(Date:7/11/2014)... 2014 Research and Markets  has announced ... 2014-2018" report to their offering. ... is a hollow needle commonly used with a syringe ... extract fluids from it. A hypodermic needle is used ... that cannot be ingested. Hypodermic needles are broadly classified ...
Breaking Medicine Technology:New Technologies Transforming Consumer Marketing Research Playbook 2Global and Chinese Medical X-ray Film Industry Report 2014 2Global Hypodermic Needles Market 2014-2018: Key Vendors are Becton, Dickinson and Co, Covidien, Retractable Technologies and Terumo Corp. 2Global Hypodermic Needles Market 2014-2018: Key Vendors are Becton, Dickinson and Co, Covidien, Retractable Technologies and Terumo Corp. 3
... (Nasdaq: NVAX ) announced today that it has ... H1N1 influenza vaccine in Mexico in collaboration with Avimex ... and pharmaceutical products for use in Mexico and more ... is providing financial support for the trial and is ...
... SHENYANG, China, Oct. 20 /PRNewswire-Asia-FirstCall/ -- 3SBio ... China-based biotechnology,company focused on researching, developing, manufacturing and marketing,biopharmaceutical ... of shareholders held on October 12, 2009. , ... re-elected Dr. Jing Lou and Mr.,Moujia Qi to serve ...
Cached Medicine Technology:Novavax Launches Pivotal Clinical Study of Novel 2009 H1N1 VLP Flu Vaccine in Mexico 2Novavax Launches Pivotal Clinical Study of Novel 2009 H1N1 VLP Flu Vaccine in Mexico 3Novavax Launches Pivotal Clinical Study of Novel 2009 H1N1 VLP Flu Vaccine in Mexico 4Novavax Launches Pivotal Clinical Study of Novel 2009 H1N1 VLP Flu Vaccine in Mexico 5
... ARUP Laboratories is a national reference laboratory ... research and development. ARUP offers an extensive ... medical tests in clinical and anatomic pathology. ... Laboratories' clients include more than half of ...
... reference laboratory and a worldwide leader in ... an extensive test menu of highly complex ... anatomic pathology. Owned by the University of ... half of the nation's university teaching hospitals ...
... reference laboratory and a worldwide leader in ... an extensive test menu of highly complex ... anatomic pathology. Owned by the University of ... half of the nation's university teaching hospitals ...
... ARUP Laboratories is a national reference ... laboratory research and development. ARUP offers an ... unique medical tests in clinical and anatomic ... ARUP Laboratories' clients include more than half ...
Medicine Products: