Navigation Links
Study sheds light on role of stem cells in children's brain tumor
Date:1/10/2010

New research from scientists at Queen Mary, University of London shows how the most common type of children's brain cancer can arise from stem cells.

Scientists know relatively little about medulloblastomas or why some cases respond better to treatments than others.

The new research, published today in Oncogene*, shows that medulloblastomas can grow from a type of brain stem cell and that these cancers are a distinct form of the disease which may require a completely different approach to treatment.

Medulloblastomas account for one in five of all children's brain tumours. They are most common in children between the ages of three and eight but they can also affect young adults.

Silvia Marino, Professor of Neuropathology at Queen Mary, University of London, led the study. She said: "This type of brain tumour can pose a great challenge to doctors. In some children, treatment works well but in others the cancer is aggressive and far harder to treat.

"As scientists we've been trying to understand how these cancers which look the same can behave so differently.

"This study is a major advance for us because it shows for the first time that some of these tumours develop from endogenous stem cells.

"This is important for two reasons. First, it could help us to tell which cancers will respond well to treatment and which will need a more aggressive therapy. Second, this new understanding could help us to find much-needed new drugs for the disease."

Previous research has shown that human brains contain a small number of stem cells called neural stem cells - which enable the brain to repair itself to some degree. Professor Marino and her team studied equivalent cells taken from mouse brains.

They found that two particular genes called Rb and p53, which are already known to play a role in cancer, could malfunction in these cells and allow the cells to grow uncontrollably. They also fou
'/>"/>

Contact: Sian Halkyard
s.halkyard@qmul.ac.uk
44-797-009-6175
Queen Mary, University of London
Source:Eurekalert

Page: 1 2

Related medicine news :

1. Study explains why light worsens migraine headaches
2. Abraxis Provides Overview Of ABRAXANE Study
3. Study Suggests Way to Mop Up Leukemia Cells
4. Periodic Paralysis Study Reveals Gene Causing Disorder
5. UCLA study shows metformin is safe for patients with advanced heart failure and diabetes mellitus
6. Technology new gateway into treatment for problem alcohol users: Study
7. Few breast cancer surgeons follow quality of care standards, U-M study finds
8. Study shows serious emotional disturbances among children after Katrina
9. Study links restless leg syndrome with erectile dysfunction in older men
10. Study identifies those elderly most at risk for major depression
11. Despite Earlier Doubts, Feinstein Study Shows Fetal Transplants May Benefit Parkinson's Patients Over Age 60
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:12/26/2014)... December 26, 2014 Plugin and template developers ... Volume 5 Plugin for Final Cut Pro X. , “TransPack ... light tool to pull off an industry professional look” Said ... their hands on TransPack Volume 5, a new level of ... a set of over 50 Final Cut Pro X transitions ...
(Date:12/26/2014)... 26, 2014 Parker & Sons, ... best in heating, cooling and plumbing contractor services ... emergency services in 2014 with regard to air-conditioning ... Arizona is known for its incredibly hot summers. ... the intricacies and details of a wide variety ...
(Date:12/25/2014)... Dallas, TX (PRWEB) December 26, 2014 ... Analysis to 2023” focuses on the current treatment landscape, ... colorectal cancer market. TS-1 is an anti-cancer drug which ... administered orally and is also used for treating gastric ... gimestat and otastat potassium. The drug was first approved ...
(Date:12/25/2014)... CA (PRWEB) December 25, 2014 The short ... was created in honor of a true 9/11 hero, ... two film festivals including the 24 hours of Nuremberg International ... in Bangladesh. , Actress, screenwriter and director Luciana ... produce this film together with her husband, Gregory Graham ...
(Date:12/25/2014)... December 25, 2014 Recently, LunaDress.co.uk has updated its ... and related accessories. Now, all of the models at LunaDress.co.uk come ... a groom lifts the wedding veil can turn out to be ... charm. A wedding veil can always bring surprise to a wedding. ... on how to choose veils for a big day . ...
Breaking Medicine News(10 mins):Health News:Today a new plugin was announced from Pixel Film Studios, TransPack Volume 5 for Final Cut Pro X 2Health News:Parker & Sons Announces Record Demand For 24 Hour Emergency Services In 2014 With Regard To Air-Conditioning Systems 2Health News:Parker & Sons Announces Record Demand For 24 Hour Emergency Services In 2014 With Regard To Air-Conditioning Systems 3Health News:TS-1 Colorectal Cancer Market Analysis and Forecast to 2023 Report at RnRMarketReserach.com 2Health News:TS-1 Colorectal Cancer Market Analysis and Forecast to 2023 Report at RnRMarketReserach.com 3Health News:The True 9/11 Hero Story “Color of Honor” Premieres in Germany and Bangladesh: Luciana Lagana Plays the Mother of the Lead and Co-Produces with Blaise Dolcemaschio. 2Health News:The True 9/11 Hero Story “Color of Honor” Premieres in Germany and Bangladesh: Luciana Lagana Plays the Mother of the Lead and Co-Produces with Blaise Dolcemaschio. 3Health News:LunaDress Provides Professional Tips On Shopping Wedding And Prom Dresses 2
... Today,s Local Winners Eligible for Consideration in National ... Today, the Society of Gastroenterology Nurses and Associates ... gastroenterology and endoscopy, and Procter and Gamble Pharmaceuticals ... Asacol(R) (mesalamine) delayed-release tablets, are proud to support ...
... Texas, March 25 Go Healthy, Inc. (Pink Sheets: GOHE) ... Interest from the Mandate Officer for the China Shenyang Company ... very favorable China Development Loan Package.Stuart Evey, Chairman of Go ... are quite pleased to see the support of our operating ...
... Healthcare Group at Frost & Sullivan ... Briefing Presentation on the European Medical Imaging Equipment ... 2009, at 4 p.m. GMT.(Logo: http://www.newscom.com/cgi-bin/prnh/20081117/FSLOGO )In ... safety standard was introduced, requiring that manufacturers of ...
... framework to meet Continua Health Alliance requirements for remote ... ZigBee(R) Alliance today announces it has completed development of ... Health Care will enable new ways to help people ... healthcare costs by providing a variety of remote health ...
... Life Line Screening corroborates research recently presented at the Society ... the ankle-brachial index in identifying high-risk individuals previously thought to ... ... Independence, OH (PRWEB) March 25, 2009 ...
... as Liaison Counsel and taking active roles in the Federal Court ... nephrogenic systemic fibrosis . The Federal Judge presiding over these ... , ... Cleveland, Ohio (PRWEB) March 25, 2009 -- Since ...
Cached Medicine News:Health News:Nationwide 'GI Nurses & Associates Day' Celebrates Contributions of Gastroenterology and Endoscopy Professionals 2Health News:Nationwide 'GI Nurses & Associates Day' Celebrates Contributions of Gastroenterology and Endoscopy Professionals 3Health News:Nationwide 'GI Nurses & Associates Day' Celebrates Contributions of Gastroenterology and Endoscopy Professionals 4Health News:Go Healthy Announces Receipt of Letter of Interest to Fund Distribution, Production, Packaging, Concept Stores and Bottling Facilities 2Health News:Leveraging the Third Amendment Ruling the Risk Management Process: Frost & Sullivan's Assessment of Regulations for Medical Imaging Equipment in Europe 2Health News:Leveraging the Third Amendment Ruling the Risk Management Process: Frost & Sullivan's Assessment of Regulations for Medical Imaging Equipment in Europe 3Health News:New ZigBee Health Care Profile: Helping People Live Healthier and Independent Lives 2Health News:New ZigBee Health Care Profile: Helping People Live Healthier and Independent Lives 3Health News:Life Line Screening Data on Peripheral Arterial Disease Validated 2Health News:Cleveland Trials Set In Nephrogenic Systemic Fibrosis (NSF) Gadolinium MRI Side Effects Cases 2Health News:Cleveland Trials Set In Nephrogenic Systemic Fibrosis (NSF) Gadolinium MRI Side Effects Cases 3Health News:Cleveland Trials Set In Nephrogenic Systemic Fibrosis (NSF) Gadolinium MRI Side Effects Cases 4
(Date:12/24/2014)... 23, 2014 ResMed (NYSE: RMD ) ... against Chinese medical device manufacturer BMC Medical Co., Ltd. ... BMC,s masks listed below infringe ResMed,s patents, and entered an ... in the United States : ... , Willow nasal pillows mask , iVolve full ...
(Date:12/24/2014)... DALLAS , Dec. 23, 2014  Lockton ... operation of Lockton Companies, announced the addition of ... Foerster will join Lockton Dunning,s Pharmacy Consulting team, ... years of relevant industry experience to the position.  ... Managed Market Sales at Diplomat Specialty Pharmacy, where ...
(Date:12/24/2014)... RALEIGH, N.C. , Dec. 23, 2014 /PRNewswire/ ... (NASDAQ: ENDP ) (TSX: ENL), and BioDelivery ... today that they have submitted a New Drug Application ... Food and Drug Administration (FDA).  Buprenorphine HCl Buccal Film ... enough to require daily, around-the-clock, long-term opioid treatment and ...
Breaking Medicine Technology:ResMed Wins Patent Infringement Lawsuit Against Chinese Manufacturer BMC Medical 2Kim Foerster Joins Lockton Companies 2Endo Pharmaceuticals and BioDelivery Sciences Announce NDA Submission for Buprenorphine HCl Buccal Film for the Management of Moderate to Severe Chronic Pain 2Endo Pharmaceuticals and BioDelivery Sciences Announce NDA Submission for Buprenorphine HCl Buccal Film for the Management of Moderate to Severe Chronic Pain 3Endo Pharmaceuticals and BioDelivery Sciences Announce NDA Submission for Buprenorphine HCl Buccal Film for the Management of Moderate to Severe Chronic Pain 4Endo Pharmaceuticals and BioDelivery Sciences Announce NDA Submission for Buprenorphine HCl Buccal Film for the Management of Moderate to Severe Chronic Pain 5
... is a national reference laboratory and a ... development. ARUP offers an extensive test menu ... in clinical and anatomic pathology. Owned by ... include more than half of the nation's ...
... ARUP Laboratories is a national reference laboratory ... research and development. ARUP offers an extensive ... medical tests in clinical and anatomic pathology. ... Laboratories' clients include more than half of ...
... national reference laboratory and a worldwide leader ... offers an extensive test menu of highly ... and anatomic pathology. Owned by the University ... than half of the nation's university teaching ...
... ARUP Laboratories is a national reference laboratory ... research and development. ARUP offers an extensive ... medical tests in clinical and anatomic pathology. ... Laboratories' clients include more than half of ...
Medicine Products: