Navigation Links
Study says screening accounts for much of black/white disparity in colorectal cancer

ATLANTA April 19, 2012 A new study finds differences in screening account for more than 40 percent of the disparity in colorectal cancer incidence and nearly 20 percent of colorectal cancer mortality between blacks and whites. Differences in stage-specific survival, which likely reflect differences in treatment account for additional 35% of the black-white disparity in colorectal cancer mortality rates. The study, appearing early online in Cancer Epidemiology Biomarkers and Prevention, concludes that equal access to care could substantially reduce the racial disparities in colorectal cancer (CRC) rates.

Previous studies have identified considerable disparities in CRC incidence and mortality rates between blacks and whites in the United States. For the new study, researchers led by Iris Lansdorp-Vogelaar, a visiting scientist at the American Cancer Society when this project was conceived and developed , and now with Erasmus Medical Center, Rotterdam, The Netherlands, used a computer simulation model to apply the screening and survival rates seen among whites to the population of black Americans 50 and over, then compared those to actual, "observed" incidence and mortality rates in blacks to calculate how much of the existing racial disparities in CRC rates are attributable to differences in screening and/or stage-specific relative survival.

They found that applying the screening pattern observed among whites to blacks would close the disparity gap in CRC incidence rates in age 50 and older from 28.2 to 16.4 cases per 100,000. Screening would decrease the mortality gap from 26.8 to 21.6 deaths per 100,000. If blacks had the stage-specific relative survival of whites, the disparity in CRC mortality rates would decrease even further, to 17.2 deaths per 100,000. And when combined, the screening pattern and stage-specific relative CRC survival of whites would decrease disparity in CRC mortality to 12.4 deaths per 100,000.

The report finds differences in CRC screening explained 42% of the observed disparity in CRC incidence between blacks and whites and 19% of disparity in CRC mortality. Stage specific relative CRC survival differences explained 36% of the disparity in CRC mortality. Together, according to the study, differences in screening and survival explained 54% of disparity in CRC mortality. The authors say equalizing access to care could substantially reduce the racial disparities in CRC burden.

As for the remaining 46% to 58% of the disparity in CRC incidence and mortality, known or unknown lifestyle factors are the most likely candidates for the gap. Those include alcohol, smoking, obesity, and meat consumption, which increase the risk of CRC, as well as physical activity and postmenopausal hormone replacement therapy (in women), which decrease risk.


Contact: David Sampson
American Cancer Society

Related medicine news :

1. Eating More Foods Rich in Omega-3s May Lower Alzheimers Risk: Study
2. Antipsychotics Do Help Many With Schizophrenia, Study Finds
3. Study finds overmanagement of benign breast disease
4. Less Invasive Heart Valve Replacement Works for Elderly: Study
5. Aspirin as Effective as Warfarin for Heart Failure: Study
6. Study Redefines What a Healthy Vagina Is
7. Once-Banned Bird Flu Study Suggests Pandemic Threat Is Real
8. Genetically modified T cell therapy shown to be safe, lasting in decade-long study of HIV patients
9. UNC study shows potential to revive abandoned cancer drug by nanoparticle drug delivery
10. Clues to Slacker Behavior Found in Brain, Study Says
11. Women More Likely to Survive Melanoma Than Men: Study
Post Your Comments:
(Date:6/26/2016)... Lake Orion, Clarkston, Michigan (PRWEB) , ... June ... ... direction with respect to fertility once they have been diagnosed with endometriosis. These ... tolerable intercourse but they also require a comprehensive approach that can help for ...
(Date:6/25/2016)... ... , ... The temporary closing of Bruton Memorial Library on June 21 due to a possible ... often overlooked aspect of head lice: the parasite’s ability to live away from a human ... but a necessary one in the event that lice have simply gotten out of control. ...
(Date:6/25/2016)... ... 25, 2016 , ... As a lifelong Southern Californian, Dr. Omkar Marathe earned ... the David Geffen School of Medicine at UCLA. He trained in Internal Medicine at ... fellowship in hematology/oncology at the UCLA-Olive View-Cedars Sinai program where he had the opportunity ...
(Date:6/25/2016)... ... June 25, 2016 , ... Conventional wisdom preaches the benefits ... terms of the latter, setting the bar too high can result in disappointment, perhaps ... slow progress toward their goal. , Research from reveals that ...
(Date:6/24/2016)... ... June 24, 2016 , ... June 19, 2016 is World ... with chronic pain and the benefits of holistic treatments, Serenity Recovery Center ... with Sickle Cell Disease. , Sickle Cell Disease (SCD) is a disorder of the ...
Breaking Medicine News(10 mins):
(Date:6/24/2016)... , June 24, 2016 The Academy of ... recommendations that would allow biopharmaceutical companies to ... entities that make formulary and coverage decisions, a move ... of new medicines. The recommendations address restrictions ... appear on the drug label, a prohibition that hinders ...
(Date:6/24/2016)... and SAN CLEMENTE, Calif. , June 24, ... -based mobile pulmonary function testing company, is now able to perform ... developed by ndd Medical Technologies , Inc. ... in hospital-based labs.  Thanks to ndd,s EasyOne PRO ® , ARL ... can get any needed testing done in the comfort of her ...
(Date:6/24/2016)... -- According to a new market research ... Safety Pen Needles), Needle Length (4mm, 5mm, 6mm, 8mm, ... Purchase (Retail, Non-Retail) - Trends & Global Forecasts to ... for the forecast period of 2016 to 2021. This ... 2021 from USD 1.65 Billion in 2016, growing at ...
Breaking Medicine Technology: