Navigation Links
Study says screening accounts for much of black/white disparity in colorectal cancer
Date:5/3/2012

ATLANTA April 19, 2012 A new study finds differences in screening account for more than 40 percent of the disparity in colorectal cancer incidence and nearly 20 percent of colorectal cancer mortality between blacks and whites. Differences in stage-specific survival, which likely reflect differences in treatment account for additional 35% of the black-white disparity in colorectal cancer mortality rates. The study, appearing early online in Cancer Epidemiology Biomarkers and Prevention, concludes that equal access to care could substantially reduce the racial disparities in colorectal cancer (CRC) rates.

Previous studies have identified considerable disparities in CRC incidence and mortality rates between blacks and whites in the United States. For the new study, researchers led by Iris Lansdorp-Vogelaar, a visiting scientist at the American Cancer Society when this project was conceived and developed , and now with Erasmus Medical Center, Rotterdam, The Netherlands, used a computer simulation model to apply the screening and survival rates seen among whites to the population of black Americans 50 and over, then compared those to actual, "observed" incidence and mortality rates in blacks to calculate how much of the existing racial disparities in CRC rates are attributable to differences in screening and/or stage-specific relative survival.

They found that applying the screening pattern observed among whites to blacks would close the disparity gap in CRC incidence rates in age 50 and older from 28.2 to 16.4 cases per 100,000. Screening would decrease the mortality gap from 26.8 to 21.6 deaths per 100,000. If blacks had the stage-specific relative survival of whites, the disparity in CRC mortality rates would decrease even further, to 17.2 deaths per 100,000. And when combined, the screening pattern and stage-specific relative CRC survival of whites would decrease disparity in CRC mortality to 12.4 deaths per 100,000.

The report finds differences in CRC screening explained 42% of the observed disparity in CRC incidence between blacks and whites and 19% of disparity in CRC mortality. Stage specific relative CRC survival differences explained 36% of the disparity in CRC mortality. Together, according to the study, differences in screening and survival explained 54% of disparity in CRC mortality. The authors say equalizing access to care could substantially reduce the racial disparities in CRC burden.

As for the remaining 46% to 58% of the disparity in CRC incidence and mortality, known or unknown lifestyle factors are the most likely candidates for the gap. Those include alcohol, smoking, obesity, and meat consumption, which increase the risk of CRC, as well as physical activity and postmenopausal hormone replacement therapy (in women), which decrease risk.


'/>"/>

Contact: David Sampson
david.sampson@cancer.org
American Cancer Society
Source:Eurekalert

Related medicine news :

1. Eating More Foods Rich in Omega-3s May Lower Alzheimers Risk: Study
2. Antipsychotics Do Help Many With Schizophrenia, Study Finds
3. Study finds overmanagement of benign breast disease
4. Less Invasive Heart Valve Replacement Works for Elderly: Study
5. Aspirin as Effective as Warfarin for Heart Failure: Study
6. Study Redefines What a Healthy Vagina Is
7. Once-Banned Bird Flu Study Suggests Pandemic Threat Is Real
8. Genetically modified T cell therapy shown to be safe, lasting in decade-long study of HIV patients
9. UNC study shows potential to revive abandoned cancer drug by nanoparticle drug delivery
10. Clues to Slacker Behavior Found in Brain, Study Says
11. Women More Likely to Survive Melanoma Than Men: Study
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:6/25/2016)... ... June 25, 2016 , ... On Friday, June 10, Van ... Wellness at Work award to iHire in recognition of their exemplary accomplishments in worksite ... 7th annual Maryland Workplace Health & Wellness Symposium at the BWI Marriott in Linthicum ...
(Date:6/24/2016)... (PRWEB) , ... June 24, 2016 , ... Those who ... with these feelings, many turn to unhealthy avenues, such as drug or alcohol abuse, ... Marne, Michigan, has released tools for healthy coping following a traumatic event. , Trauma ...
(Date:6/24/2016)... ... June 24, 2016 , ... ... Sessions in Dallas that it will receive two significant new grants to support ... as PHA marked its 25th anniversary by recognizing patients, medical professionals and scientists ...
(Date:6/24/2016)... Diego, CA (PRWEB) , ... June 24, 2016 , ... ... with the American Cancer Society and the Road To Recovery® program to drive cancer ... to seniors and other adults to ensure the highest quality of life and ongoing ...
(Date:6/24/2016)... (PRWEB) , ... June 24, 2016 , ... ... today at the Clinical Decision Making in Emergency Medicine conference in Ponte Vedra ... authored journal articles published in Emergency Medicine Practice and Pediatric Emergency ...
Breaking Medicine News(10 mins):
(Date:6/26/2016)... June 26, 2016 One of Australia,s ... the formation of a new biotechnology company, Noxopharm Limited [ABN 50 ... an IPO and to list on the ASX. Noxopharm ... ready to enter a Phase 1 clinical study later this year. ... address one of the biggest problems facing cancer patients - the ...
(Date:6/26/2016)... -- Jazz Pharmaceuticals plc (Nasdaq: JAZZ ) ... Improvements Act of 1976, as amended ("HSR"), with respect ... Nasdaq: CPXX ) expired effective June 24, ... As previously announced on May 31, 2016, Jazz Pharmaceuticals ... which Jazz Pharmaceuticals has commenced a tender offer for ...
(Date:6/26/2016)... OTTAWA, Ontario , June 27, 2016  VMS ... the Company,s Board will take whatever measures required to ... the Company,s stock which is currently listed on the ... S Wexler, Company Chairman and CEO, "We are seeing ... be difficult to understand, not only by the Company, ...
Breaking Medicine Technology: