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Study says lead may be the culprit in ADHD
Date:1/28/2010

etween blood lead and both parent and teacher ratings of ADHD symptoms, including both hyperactivity and attention problems. In both studies, the connection was independent of IQ, family income, race, or maternal smoking during pregnancy.

Nigg offers a causal model for the disabling symptoms associated with ADHD: Lead attaches to sites in the brain's striatum and frontal cortex, where it acts on the genes in these regionscausing them to turn on or remain inactive. Gene activity shapes the development and activity of these brain regions. By disrupting brain activity, the toxin in turn alters psychological processes supported by these neurons, notably cognitive control. Finally, diminished cognitive control contributes to hyperactivity and lack of vigilance. Nigg describes his new data and his explanatory model in the February issue of the journal Current Directions in Psychological Science.


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Contact: Catherine Allen-West
cwest@psychologicalscience.org
202-293-9300
Association for Psychological Science
Source:Eurekalert

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