Navigation Links
Study reveals potential immune benefits of vitamin D supplements in healthy individuals
Date:3/20/2013

of the two-month period and again at the end. A broad gene expression analysis was conducted on these samples and more than 22,500 genes were investigated to see if their activity increased or decreased as a result of the vitamin D intake.

At the end of the pilot, the group that received 2000 IUs achieved a vitamin D status of 34 ng/mL, which is considered sufficient, while the group that received 400 IUs achieved an insufficient status of 25 ng/mL.

The results of the gene expression analysis indicated statistically significant alterations in the activity of 291 genes. Further analysis showed that the biologic functions associated with the 291 genes are related to 160 biologic pathways linked to cancer, autoimmune diseases, infectious diseases and CVD.

Examining gene response elements, or sequences of DNA bases that interact with vitamin D receptors to regulate gene expression, they also identified new genes related to vitamin D status. To ensure that their observations were accurate, the researchers looked at 12 genes whose level of expression does not change, and those genes remained stable throughout the trial period.

"This study reveals the molecular fingerprints that help explain the non-skeletal health benefits of vitamin D," said Michael F. Holick, PhD, MD, professor of medicine, physiology and biophysics at BUSM and leading vitamin D expert who served as the study's corresponding author. "While a larger study is necessary to confirm our observations, the data demonstrates that improving vitamin D status can have a dramatic effect on gene expression in our immune cells and may help explain the role of vitamin D in reducing the risk for CVD, cancer and other diseases."


'/>"/>

Contact: Jenny Eriksen
jenny.eriksen@bmc.org
617-638-6841
Boston University Medical Center
Source:Eurekalert

Page: 1 2

Related medicine news :

1. Study Suggests Vaccine May Help Kids With Brain Cancer
2. Study reveals how cancer drug causes diabetic-like state
3. Coffee Drinking in Pregnancy Wont Lead to Sleepless Baby: Study
4. Lower GI problems plague many with rheumatoid arthritis, Mayo Clinic study finds
5. Veggies Like Broccoli, Cabbage May Help Fight Breast Cancer: Study
6. No Added Cancer Risk From Hip Replacement Materials: Study
7. Reported Decline in U.S. Pneumonia Deaths May Be False: Study
8. Early Study Finds Some Promise for Lung Cancer Vaccine
9. Narcissists Often Ace Job Interviews, Study Finds
10. Sexual objectification of female artists in music videos exists regardless of race, MU study finds
11. Soy may alleviate hot flashes in menopause, large-scale study finds
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:11/21/2014)... to make it tougher for people to misuse prescription ... approved a new hydrocodone tablet that,s designed to help ... brand name Vicodin -- is a powerful opioid painkiller ... addictions across the United States. The FDA said ... extended-release tablet to treat pain severe enough to require ...
(Date:11/21/2014)... Scientists say they,ve mapped the genome -- the genetic "blueprint" ... in hopes it might help others with this very rare ... Genome Biology , the tapeworm was removed from the brain ... infection is so rare worldwide and completely unexpected in this ... worm was pulled out from the brain," study lead author ...
(Date:11/21/2014)... PLYMOUTH and WOBURN, Mass. (PRWEB) November 21, 2014 ... will present two free workshops titled “Massachusetts Insurance Funding ... autism spectrum disorder (ASD) navigate their way through the ... must be covered under Massachusetts law and the most ... take place on Thursday, Dec. 4 from 6-8:00 p.m. ...
(Date:11/21/2014)... Orange County, CA (PRWEB) November 21, 2014 ... be featured in an upcoming episode of Innovations with ... 2015. Dates and show times TBA. , Big Bud ... with information for growing, harvesting, and utilization of medical ... look at Big Bud Farms’ wide variety of products ...
(Date:11/21/2014)... 21, 2014 Launched today on the ... an all-in-one senior care coordination tool designed to make ... simple and intuitive for family members and caregivers (e.g. ... Now, the family caregiver or home health aide providing ... health data, medical records, goals, schedules, and even final ...
Breaking Medicine News(10 mins):Health News:FDA Approves 'Abuse-Resistant' Narcotic Painkiller 2Health News:FDA Approves 'Abuse-Resistant' Narcotic Painkiller 3Health News:Ick! Tapeworm Infecting Man's Brain Yields Genetic Secrets 2Health News:Center for Autism and Related Disorders to Host Massachusetts Autism Insurance Workshops for Parents 2Health News:Big Bud Farms to be Featured in Upcoming Episode of Innovations with Ed Begley Jr. 2Health News:Comprehensive Senior Care Application Launched on Apple App Store 2
... LifeCare Holdings, Inc. (the,"Company") today announced its operating results ... Our net patient service revenue increased by $6.4 million, ... $88.8 million from $82.4 million,for the comparable period in 2007. ... than the same period in 2007., The increase in ...
... Patient safety in hospitals focus of 48 NQF-endorsed ... patient,safety remains a major hurdle in the United ... voluntary consensus standards focused on,measuring the performance of ... readmission, and prevention and care,of venous thromboembolism., ...
... - QLT Inc. (NASDAQ: QLTI; TSX:,QLT) announced today that ... the land and building comprising its corporate headquarters and ... with the closing of the transaction, QLT will enter ... continue its operations., "We are very pleased that ...
... appear to help quality of life for lung cancer ... -- Adding chemotherapy to other treatments being giving to ... asbestos exposure, does not appear to improve either survival ... which is usually fatal, is a cancer of the ...
... Corporation,("Select") today announced results for its first quarter ... ended March 31, 2008, net operating revenues,increased 17.4% ... the same,quarter, prior year. Income from operations decreased ... the same quarter, prior year. Net income,decreased 47.9% ...
... Governor Paterson,s leadership in proposing prescription,drug marketing reform ... AARP strongly believes,New York has a paramount interest ... address the undue influence that,pharmaceutical companies have over ... but the treatment they receive., The reforms ...
Cached Medicine News:Health News:LifeCare Holdings, Inc. Announces First Quarter Results 2Health News:LifeCare Holdings, Inc. Announces First Quarter Results 3Health News:LifeCare Holdings, Inc. Announces First Quarter Results 4Health News:LifeCare Holdings, Inc. Announces First Quarter Results 5Health News:LifeCare Holdings, Inc. Announces First Quarter Results 6Health News:LifeCare Holdings, Inc. Announces First Quarter Results 7Health News:LifeCare Holdings, Inc. Announces First Quarter Results 8Health News:LifeCare Holdings, Inc. Announces First Quarter Results 9Health News:National Quality Forum Endorses Consensus Standards for Quality of Hospital Care 2Health News:National Quality Forum Endorses Consensus Standards for Quality of Hospital Care 3Health News:National Quality Forum Endorses Consensus Standards for Quality of Hospital Care 4Health News:National Quality Forum Endorses Consensus Standards for Quality of Hospital Care 5Health News:QLT Inc. announces agreement for sale of real estate 2Health News:QLT Inc. announces agreement for sale of real estate 3Health News:Chemo for Mesothelioma Offers Limited Survival Benefits 2Health News:Select Medical Corporation Announces Results for First Quarter Ended March 31, 2008 2Health News:Select Medical Corporation Announces Results for First Quarter Ended March 31, 2008 3Health News:Select Medical Corporation Announces Results for First Quarter Ended March 31, 2008 4Health News:Select Medical Corporation Announces Results for First Quarter Ended March 31, 2008 5Health News:Select Medical Corporation Announces Results for First Quarter Ended March 31, 2008 6Health News:Select Medical Corporation Announces Results for First Quarter Ended March 31, 2008 7Health News:Select Medical Corporation Announces Results for First Quarter Ended March 31, 2008 8Health News:Select Medical Corporation Announces Results for First Quarter Ended March 31, 2008 9Health News:AARP Statement on Governor's Bill for Prescription Drug Marketing Reform and Transparency 2
(Date:11/21/2014)...  The University of Maryland,s A. James Clark School ... the new A. James Clark Hall at the University ... transformative new engineering and biomedical technologies to accelerate advancements ... a.m. on November 21 at the site of the ... to the Jeong H. Kim Engineering Building, the event ...
(Date:11/21/2014)... 2014 In September 2014, the staff at ... a new product development plan that started with the ... lab coat , aptly named "Vera G.," after ... the world. The new women,s designer lab coat is ... sleek envelope collar, vertical princess and high waist seaming, ...
(Date:11/21/2014)... 2014  Heated dialogue in recent months about the ... treatments to Gilead,s new hepatitis C drug Harvoni® – ... questioning what it means to put a price on ... And while drug pricing is one of the most ... a general business and ethical standpoint – it is ...
Breaking Medicine Technology:University of Maryland Breaks Ground for A. James Clark Hall 2University of Maryland Breaks Ground for A. James Clark Hall 3University of Maryland Breaks Ground for A. James Clark Hall 4Medelita Introduces Medical Industry's First Limited Edition Women's Designer Lab Coat 2"The Price of Global Health" Tackles Worldwide Drug-Pricing Debate 2"The Price of Global Health" Tackles Worldwide Drug-Pricing Debate 3"The Price of Global Health" Tackles Worldwide Drug-Pricing Debate 4"The Price of Global Health" Tackles Worldwide Drug-Pricing Debate 5
... PowerSuite™ holmium laser combines excellent cutting, ... virtually bloodless procedures. It is also ... gall bladder stones of all compositions, ... tool. Because its laser light is ...
... VersaPulse® PowerSuite™ holmium laser combines excellent ... precise, virtually bloodless procedures. It is ... and gall bladder stones of all ... surgical tool. Because its laser light ...
... leg position for the seated patient and helps ... foot/ankle at 90 degrees to the leg. The ... stand. Stockinette is pulled over the foot and ... a routine fashion. The cast stand is slipped ...
... provides the highest level of protection ... lead protective eyewear. Consistent lens ... allowed. Mfg supervised by Licensed and ... meet or exceed standards for optical ...
Medicine Products: