Navigation Links
Study reveals no impact of age on outcome in chronic myeloid leukemia patients treated with imatinib
Date:3/30/2011

(WASHINGTON, March 30, 2011) While the median age at diagnosis for chronic myeloid leukemia (CML) is over 60 years old and incidence increases dramatically with age,limited data are available about the long-term outcome for older patients treated with imatinib, the standard first-line therapy used to treat CML. Results from a study published today in Blood, the Journal of the American Society of Hematology, reveal that age does not affect response to imatinib and study investigators conclude that overall survival for CML is similar in older and younger patients treated with the drug.

Two widely used prognostic scores for CML, the Sokal and EURO risk scores, have historically identified older age as a predicting factor of lower response rate and poorer outcome. However, these risk scores were validated before imatinib was introduced as a therapy for CML and may now hold less relevance, as imatinib has dramatically improved the prognosis for CML patients.

"Older age has typically been considered a poor prognostic factor in patients with CML and has a negative impact on response rates and long-term survival, regardless of treatment," said Gabriele Gugliotta, MD, co-author of the study and Fellow in the Department of Hematology and Oncology at St. Orsola-Malpighi Hospital at the University of Bologna in Bologna, Italy. "Our study focused on disease progression, treatment response, and survival of this specific patient population to assess the role of imatinib in older patients."

To test whether age at diagnosis is a valid predictor of response, researchers from several institutions in Italy conducted an analysis of 559 patients with early chronic phase CML (six months or less from diagnosis to start of imatinib treatment) who were enrolled in three concurrent clinical tria
'/>"/>

Contact: Lindsey Love
webmaster@hematology.org
202-552-4925
American Society of Hematology
Source:Eurekalert

Page: 1 2

Related medicine news :

1. Case study reports singing lowers patients blood pressure prior to surgery
2. Study finds surprising gender differences related to sexual harassment
3. Parkinsons Drugs Linked to Behavior Problems in Study
4. Conflicts of Interest Cloud Heart Treatment Guidelines: Study
5. Negative attitudes toward fat bodies going global, study finds
6. Airport Scanners Appear Safe, Study Finds
7. Surgeon Enthusiasm May Spur Higher Rates of Back Pain Procedures: Study
8. Teens Who Smoke Early Often Try Pot Later, Study Finds
9. Study finds changes in incidence of end-stage renal disease from lupus nephritis
10. Some women worry too much about breast cancer returning, U-M study finds
11. Laughter, Music May Lower Blood Pressure, Study Says
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:7/12/2014)... PA (PRWEB) July 12, 2014 “After my mom’s ... then had a stroke and loss the use of his left ... to design a way to help people like them enjoy eating ... created a prototype for the PATRICIA CAROL HALL PLATE (P C ... PLATE) offers a more ergonomic way to eat for individuals who ...
(Date:7/12/2014)... York, New York (PRWEB) July 12, 2014 ... continue to move forward in U.S. courts, Bernstein Liebhard ... ties elevated metal ion levels to the failure of ... July 2nd issue of The Journal of Bone & ... had received unilateral Articular Surface Replacement prostheses at least ...
(Date:7/12/2014)... 12, 2014 For those who are unfamiliar ... readily absorb the nutrients in food. The enzymes literally break ... small enough to be absorbed by human bodies. According Dr. ... of enzymes in regular food is the cause of many ... was started by Michelle DelPresto, a mother of 3 who ...
(Date:7/12/2014)... 12, 2014 “Critical Care Therapeutics ... and Late-Stage Four-Factor PCCs and Recombinant Products to ... critical care market in the US, UK, France, ... provides an estimation of market size for 2013, ... critical care indications that are being treated using ...
(Date:7/12/2014)... (PRWEB) July 12, 2014 As reported in ... Institute of Standards and Technology), the June 25th, 2014 Supreme ... electronic discovery world. It was also met with ... depending on whether it was seen from an individual privacy ... much is fact, there is now precedent which will require ...
Breaking Medicine News(10 mins):Health News:DePuy Pinnacle Hip Lawsuit News: Bernstein Liebhard LLP Notes Release of New Study Tying Elevated Metal Ions to Metal-on-Metal Hip Failure 2Health News:DePuy Pinnacle Hip Lawsuit News: Bernstein Liebhard LLP Notes Release of New Study Tying Elevated Metal Ions to Metal-on-Metal Hip Failure 3Health News:DePuy Pinnacle Hip Lawsuit News: Bernstein Liebhard LLP Notes Release of New Study Tying Elevated Metal Ions to Metal-on-Metal Hip Failure 4Health News:New Super Digestive Enzyme, DZ10, Supercharges The Digestion Process 2Health News:Critical Care Therapeutics in Major Developed Market is Expected to Grow at a CAGR of 4.7% to $2.5 Billion in 2019 2Health News:Critical Care Therapeutics in Major Developed Market is Expected to Grow at a CAGR of 4.7% to $2.5 Billion in 2019 3Health News:Critical Care Therapeutics in Major Developed Market is Expected to Grow at a CAGR of 4.7% to $2.5 Billion in 2019 4Health News:Critical Care Therapeutics in Major Developed Market is Expected to Grow at a CAGR of 4.7% to $2.5 Billion in 2019 5Health News:Critical Care Therapeutics in Major Developed Market is Expected to Grow at a CAGR of 4.7% to $2.5 Billion in 2019 6Health News:Mobile Device Forensics Guidelines Play Key Role in Supreme Court’s Smartphone Evidence Warrant Decision 2Health News:Mobile Device Forensics Guidelines Play Key Role in Supreme Court’s Smartphone Evidence Warrant Decision 3Health News:Mobile Device Forensics Guidelines Play Key Role in Supreme Court’s Smartphone Evidence Warrant Decision 4Health News:Mobile Device Forensics Guidelines Play Key Role in Supreme Court’s Smartphone Evidence Warrant Decision 5
... you could not find the price for anything at the ... check-out clerk offered to mail you a bill, but could ... Although that sounds ridiculous, that is exactly how our nation,s ... care reform debate charges forward, the unsustainable rise in health ...
... involved with the chemopreventative effect of aspirin on colorectal adenomas, ... the Journal of the National Cancer Institute . ... polyps, but it,s not clear how it works. One hypothesis ... as C-reactive protein and others, that are markers of inflammation. ...
... might yield insights into diseases like Parkinson,s, experts say , ... genetic mutation seem to be "smarter," in the sense of ... make correct decisions quickly, a new German study suggests. , ... the prefrontal cortex of the brain, activity that is probably ...
... Oct. 12 /PRNewswire-FirstCall/ - HTDS www.htdsmedical.com (HTDS) ... Chem www.slavicabiochem.com is providing an audio recording ... Filing service. The audio recording a wav file can ... transcript and the audio recording covers scientific topics and ...
... Iowa Committee for Value in Healthcare today issued a ... health care that Congress and the Obama administration should ... The committee found that Iowa, nationally recognized for high-value ... reform. Health care providers, purchasers, payers, patient advocates and ...
... Mourning, Kidney Care Partners Call Attention to Extended Medicare ... Access to Quality Care , WASHINGTON, Oct. 12 ... advocates, dialysis professionals, care providers and manufacturers working together ... disease and kidney failure - today applauded the Congressional ...
Cached Medicine News:Health News:Regence Video Asks 'What if Everything Worked Like Health Care?' 2Health News:Regence Video Asks 'What if Everything Worked Like Health Care?' 3Health News:Gene Mutation May Speed Learning 2Health News:Slavica Bio Chem (HTDS) Subsidiary Medical Team Message 2Health News:Slavica Bio Chem (HTDS) Subsidiary Medical Team Message 3Health News:Slavica Bio Chem (HTDS) Subsidiary Medical Team Message 4Health News:Iowa Committee Makes Recommendations to Increase Value in Health Care 2Health News:Iowa Committee Makes Recommendations to Increase Value in Health Care 3Health News:Iowa Committee Makes Recommendations to Increase Value in Health Care 4Health News:Iowa Committee Makes Recommendations to Increase Value in Health Care 5Health News:Kidney Care Community Commends Congressional Black Caucus for Naming Expansion of Medicare Provisions for Kidney Failure Patients as Top Priority 2Health News:Kidney Care Community Commends Congressional Black Caucus for Naming Expansion of Medicare Provisions for Kidney Failure Patients as Top Priority 3
(Date:7/11/2014)... According to a new market ... (Endoscopes, Endoscopic Operative Devices, and Visualization Systems) - Global ... the global endoscopy devices market was valued at USD ... at a CAGR of 6.8% from 2013 to 2019, ... in 2019. Browse the full Endoscopy Devices Market ...
(Date:7/11/2014)... Neurelis, Inc. ("Neurelis") today announced an agreement ... held by Biotie to purchase Neurelis, clearing the way ... diazepam) for pediatric and adult epilepsy patients who experience ... Biotie has advanced the development program for NRL-1 and ... work required for NDA submission to the FDA.  Given ...
(Date:7/10/2014)... 2014  Breg, Inc., a premier provider of ... FreeRunner™ knee brace with new innovations to help ... return to active lifestyles.  FreeRunner,s patent-pending design acts ... support when patients need it most, and the ... Patellofemoral issues are the most common cause ...
Breaking Medicine Technology:Global Endoscopy Devices Market is Expected to Reach USD 36.9 Billion by 2019: Transparency Market Research 2Global Endoscopy Devices Market is Expected to Reach USD 36.9 Billion by 2019: Transparency Market Research 3Global Endoscopy Devices Market is Expected to Reach USD 36.9 Billion by 2019: Transparency Market Research 4Global Endoscopy Devices Market is Expected to Reach USD 36.9 Billion by 2019: Transparency Market Research 5Global Endoscopy Devices Market is Expected to Reach USD 36.9 Billion by 2019: Transparency Market Research 6Neurelis Regains Rights to Intranasal Diazepam Program 2Neurelis Regains Rights to Intranasal Diazepam Program 3Breg Introduces Knee Brace to Help Runners with Patellofemoral Pain Syndrome 2
... ... ... var shortURL = ""; BitlyCB.alertResponse = ... grab the first one. for (var r in data.results) { first_result = data.results[r]; break; } for (var key ...
... biotechnology specialist Azantis, Inc . has made a ... an effort to provide continued high quality service to ... SafetyCall International , Azantis has partnered with the recognized ... SafetyCall medical and toxicology professionals are ...
Cached Medicine Technology:Professor Steven V. Ley Speaks at WuXi PharmaTech 2Professor Steven V. Ley Speaks at WuXi PharmaTech 3Professor Steven V. Ley Speaks at WuXi PharmaTech 4Professor Steven V. Ley Speaks at WuXi PharmaTech 5Professor Steven V. Ley Speaks at WuXi PharmaTech 6Professor Steven V. Ley Speaks at WuXi PharmaTech 7Azantis Announces New Consumer Safety Program 2
Diamond Point Bone Probe with Ortho-Grip® silicone rubber palm style handles and,stainless steel impactor caps....
CapSureSP Novus 5594 is a J-shaped, endocardial, tined pacing lead. provide the stable, low pacing thresholds and large sensing potentials already proven with CapSure SP steroid-eluting leads but wi...
The Guidant Fineline II Sterox Atrial J is a steroid-eluting pacing lead designed for permanent implantation for either atrial or ventricular applications....
The Guidant Fineline II Sterox is a steroid-eluting pacing lead designed for permanent implantation for either atrial or ventricular applications....
Medicine Products: