Navigation Links
Study reveals how stem cells decide to become either skeletal or smooth muscle
Date:10/10/2007

Researchers have discovered a key protein that controls how stem cells choose to become either skeletal muscle cells that move limbs, or smooth muscle cells that support blood vessels, according to a study published today in the Proceedings of the National Academy of Sciences (PNAS). The results not only provide insight into the development of muscle types in the human fetus, but also suggest new ways to treat atherosclerosis and cancer, diseases that involve the creation of new blood vessels from stem cell reserves that would otherwise replace worn out skeletal muscle. The newly discovered mechanism also suggests that some current cancer treatments may weaken muscle, and that physician researchers should start watching to see if a previously undetected side effect exists.

Thanks to stem cells, humans develop from a single cell into a complex being with as many as 400 cell types in millions of combinations. The original, single human stem cell, the fertilized embryo, has the potential to develop into every kind of human cell. As we develop in the womb, successive generations of stem cells specialize (differentiate), with each group able to become fewer and fewer cell types. One set of mostly differentiated stem cells has the ability to become bone, blood, skeletal muscle or smooth muscle. Many human tissues keep a reserve of stem cells on hand in adulthood, ready to differentiate into replacement parts depending on the stimuli they receive. If body signals that skeletal muscle needs replacing, the stem cells take that route. If tissues signal for more blood vessels, the same stem cells may become smooth muscle that supports the lining of blood vessels.

In the current study a team of researchers at the Aab Cardiovascular Research Institute of the University of Rochester School of Medicine & Dentistry and at the University of Texas Southwestern Medical Center found that a transcription factor called myocardin may be the master regulator of whe
'/>"/>

Contact: Greg Williams
Greg_Williams@urmc.rochester.edu
University of Rochester Medical Center
Source:Eurekalert

Page: 1 2 3 4 5

Related medicine news :

1. Rural Canadians travel far for specialists: study
2. A new study surpasses Gene Therapy Hurdle
3. Tomato Sauce reduces Cancer Risk- Study
4. A question on study of Adult Stem Cell
5. Study on obesity and heart failure
6. National Lung Study in the process
7. Marijuana gateway theory strengthened by study of twins
8. Old theory of adaptation confirmed by new study
9. Study casts doubt on keyboard ills
10. Gene study links endometriosis, infertility
11. Study reveals how stress can make you sick
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:7/28/2015)... ... July 16, 2015 (PRWEB) July 28, 2015 , ... ... specializes in providing Health insurance quotes to its clients, recently announced the launch ... rates that best suits their specific needs. , Liability automobile insurance policies ...
(Date:7/28/2015)... ... July 28, 2015 , ... ... studio to measure and produce health outcomes associated with its training methods. This ... on a small group pre-post study, conducted in early 2015, training yielded an ...
(Date:7/28/2015)... (PRWEB) , ... July 28, 2015 , ... ... much-anticipated U.S. commercial launch of its ORTHALIGN PLUS® system, a palm-sized, single-use navigation ... , “OrthAlign successfully combined precision with practicality in a revolutionary way for ...
(Date:7/28/2015)... ... 28, 2015 , ... According to Kxan on June 24th a ... in lab mice. The study involving isradipine has garnered national attention and is making ... clients overcome drug and alcohol addictions. The study was conducted by the University of ...
(Date:7/28/2015)... ... ... According to WFTV on July 15th heroin overdose rates have increased ... to recent statistic Orlando suffers at least one death weekly as a direct result ... law enforcement officials are struggling to keep apace with its distribution. Officers rely on ...
Breaking Medicine News(10 mins):Health News:Nations Insurance Solutions Announces Auto, Motorcycle, and Commercial Business Insurance Quotes. 2Health News:opaJUMP Launches First Case Study in Thyroid Health: How Rebounding Helped One Woman Stabilize Her Thyroid in Seven Weeks 2Health News:opaJUMP Launches First Case Study in Thyroid Health: How Rebounding Helped One Woman Stabilize Her Thyroid in Seven Weeks 3Health News:opaJUMP Launches First Case Study in Thyroid Health: How Rebounding Helped One Woman Stabilize Her Thyroid in Seven Weeks 4Health News:opaJUMP Launches First Case Study in Thyroid Health: How Rebounding Helped One Woman Stabilize Her Thyroid in Seven Weeks 5Health News:opaJUMP Launches First Case Study in Thyroid Health: How Rebounding Helped One Woman Stabilize Her Thyroid in Seven Weeks 6Health News:opaJUMP Launches First Case Study in Thyroid Health: How Rebounding Helped One Woman Stabilize Her Thyroid in Seven Weeks 7Health News:OrthAlign, Inc. Announces U.S. Commercial Launch of ORTHALIGN PLUS®, the most complete handheld navigation device for use in Total Hip Arthroplasty Surgery 2Health News:OrthAlign, Inc. Announces U.S. Commercial Launch of ORTHALIGN PLUS®, the most complete handheld navigation device for use in Total Hip Arthroplasty Surgery 3Health News:Blood Pressure Medication May be the Key to Treating Addiction 2Health News:Blood Pressure Medication May be the Key to Treating Addiction 3Health News:Heroin Overdose Deaths Increase by 270 Percent, Orlando Takes the Lead 2Health News:Heroin Overdose Deaths Increase by 270 Percent, Orlando Takes the Lead 3
... Amalga to connect hospitals and community ... ... and efficiency of healthcare delivered to medically underserved,D.C. residents, the District ... intelligence system, to enable the,sharing of data among local hospitals and ...
... June 25th in the open-access journal PLoS Neglected ... those plaguing Africa, Asia, and Latin America are also ... States, especially women and children. These diseases ... chronic and debilitating parasitic, bacterial, and congenital infections. ...
... lost in rush to treat patients, study says , , ... can cause a breakdown in the control of methicillin-resistant ... report. , The team at the School ... in many high-income countries such as Australia, Canada and ...
... As hospitals struggle to staff,their floors in ... one,company has introduced a cost-effective way for hospitals ... LLC (NHC, http://www.nighthospitalist.com ) provides nighttime hospital coverage ... service will soon be available,nationwide., Hospitalists -- ...
... Health Care today announced the launch of the 3M™ ... needs of clinicians seeking a premium surgical mask. ... filtration media and a rayon outerlayer to deliver increased ... , Featuring a popular "duckbill" design, the 3M ...
... in Six Sectors Expected to Present to 1,000 Buy Side ... ... Group LLC, a leading,full-service mid-tier investment banking, securities and wealth management,firm will ... Grand Hyatt Hotel in NYC. This year,s conference theme was,chosen to reflect ...
Cached Medicine News:Health News:District of Columbia Primary Care Association Selects Microsoft Amalga to Improve Patient Care for the Underserved 2Health News:District of Columbia Primary Care Association Selects Microsoft Amalga to Improve Patient Care for the Underserved 3Health News:'Neglected infections of poverty' in US disable hundreds of thousands of Americans annually 2Health News:MRSA Rates Tied to Hospital Understaffing 2Health News:Night Hospitalist Company, LLC Launches First Nighttime Hospitalist Telemedicine Solution 2Health News:3M Health Care launches new high-performance surgical mask 2Health News:Maxim Group LLC to Hold Its Annual Growth Conference October 7, 2008 in New York 2Health News:Maxim Group LLC to Hold Its Annual Growth Conference October 7, 2008 in New York 3
(Date:7/28/2015)... 28, 2015  SeraCare Life Sciences, a leading ... today at the American Association of Clinical Chemistry ... agreement with the University of California, San Francisco ... Trisomy 18 (T18) and Trisomy 13 (T13) trophoblast ... "patient-like" reference materials for Non-Invasive Prenatal Testing (NIPT) ...
(Date:7/28/2015)... July 28, 2015 The Physician-Patient Alliance for ... fundraising campaign, " Surviving Your Hospital Stay ." ... they deserve! None of these patients went home from ... Executive Director, PPAHS) referring to the patient stories ... National Coalition to Promote Continuous Monitoring of Patients on ...
(Date:7/28/2015)... At the 2015 ICX Association Excellence ... 15 winners in the categories of digital signage, ... vertical markets. ContextMedia:Health proudly took home the ... success with its first-to-market Patient Education Exam ... leading provider of digital solutions at point-of-care, ...
Breaking Medicine Technology:SeraCare Life Sciences Signs License Agreement with UCSF and Announces Early Access Program for Development of Aneuploidy Reference Materials 2SeraCare Life Sciences Signs License Agreement with UCSF and Announces Early Access Program for Development of Aneuploidy Reference Materials 3Surviving Your Hospital Stay: Physician-Patient Alliance for Health & Safety Launches Fundraising for Patient Safety 2ContextMedia:Health Receives Top Award at the ICX Association Excellence Awards 2
Irrigating nucleus chopper, semi-sharp, wedge shaped inferior edge with a pointed tip, dual sideports, 20 gauge. For Phakonit cataract surgery....
Phaco chopper, a combination of a Sinskey hook and a pointed "quick chop" tip....
... Lorenz Orbital Floor Plates feature a unique ... Plates are a CP titanium and .3mm ... 0.3mm profile for optimal malleability. Universal (left/right) ... nerve cut out and smooth construction for ...
... cracker with straight shaft allows cracking ... maintains anterior chamber depth and prevents ... a design that keeps cross point ... of viscoelastic. Available with 1.5 mm ...
Medicine Products: