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Study reports adenoma detection rates are higher than current guidelines suggest in both men and women
Date:4/11/2013

centage of screened patients with at least one adenoma detected.

Results

The overall average-risk screening ADR was 33.7 percent for both sexes combined. Average risks for women and men were significantly higher than guidelines; women had a 25.4 percent risk in the study versus a 15 percent risk noted in guidelines; men had a 41.2 percent risk in the study versus a 25 percent risk noted in guidelines. Overall advanced-pathology adenoma detection was 12.2 percent for both sexes combined. There was a significantly higher advanced-pathology ADR for men (15.3 percent) versus women (8.7 percent). There was no significant difference between the genders when age was considered in both advanced-pathology and average-risk ADRs.

If the overall ADR is considered, adenoma detection is higher in men; therefore, logically, overall advanced pathology adenoma detection will be higher as well. These results, however, suggest that once an adenoma is present, the chance of an advanced-pathology adenoma is the same, regardless of sex. The researchers stated that this highlights the need for vigilance in identifying patients of both sexes with adenomas as a predictor of advanced-pathology adenomas and future CRC risk.

The researchers noted some important study limitations. The study was completed in a purely academic center by experienced endoscopists with high adenoma detection rates and as part of a study on improving adenoma detection. It is possible that these factors may have increased their detection. They also do not have data on how many of the patients were having first-time screening, although arguably a prior negative examination may make adenoma detection less likely and therefore lower their detection results. They also acknowledge that the small sample size of average-risk screening patients limits interpretation of their results. Despite these limitations, the researchers believe these results add valuable data toward understanding g
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Contact: Anne Brownsey
abrownsey@asge.org
630-570-5635
American Society for Gastrointestinal Endoscopy
Source:Eurekalert

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