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Study reports adenoma detection rates are higher than current guidelines suggest in both men and women
Date:4/11/2013

ng 25 percent. We hypothesized that ADRs for women in our average-risk screening patients also would be at least 25 percent," said study lead author Michael B. Wallace, MD, MPH, FASGE, Mayo Clinic, Jacksonville, Florida. "The ADR in our study was higher than current benchmarks for both genders; 25.4 percent for women and 41.2 percent for men. In patients with at least one adenoma, advanced-pathology adenomas were detected equally among men and women. Although the benefits of achieving supra-benchmark ADRs are unknown, high ADRs may lead to more effective colonoscopy."

Methods

The objective of the study was to determine average-risk screening ADRs and the prevalence of adenomas by location, size, shape, and degree of dysplasia in each gender. Data was collected prospectively on 2,400 outpatient colonoscopies as part of the Mayo Clinic's previous study of an endoscopist quality improvement program (EQUIP). Baseline-phase procedures were completed from August 2, 2010 through December 1, 2010, and after-training phase procedures were completed from January 5, 2011 through April 12, 2011. Data collection was suspended between phases while endoscopist training was completed. All procedures were completed by 15 experienced endoscopists.

For the purposes of this study on gender trends in adenoma detection, researchers reviewed the EQUIP database and identified all average-risk patients undergoing CRC screening. Average-risk patients were defined as those without a personal history of adenomatous polyps or a family history of CRC. A total of 864 average-risk patients were included in the study. Then researchers determined the ADR for each gender and compared them with current medical society guidelines (25 percent ADR for men, 15 percent for women). The percentages of patients in each gender with adenomas that were large, flat, contained advanced pathology, or were proximally located were compared between men and women. ADR is defined as the per
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Contact: Anne Brownsey
abrownsey@asge.org
630-570-5635
American Society for Gastrointestinal Endoscopy
Source:Eurekalert

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