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Study reports Double Balloon Endoscopy useful for diagnosis and treatment of obscure GI bleeding
Date:10/31/2008

yields were similar to those of capsule endoscopy."

Patients and Methods

This study examined 108 patients at the Nippon Medical School, Tokyo, Japan from July 2003 to February 2007 who had been referred for evaluation of obscure GI bleeding. Obscure GI bleeding was defined as overt GI bleeding or anemia in combination with stool test positive for blood of unknown cause despite negative upper and lower endoscopy. A stool blood test or fecal occult blood test (FOBT) is used to find small amounts of hidden (occult) blood in the stool. A sample of stool is tested for traces of blood.

The patients were classified into three groups before a DBE was performed: patients seen with active bleeding were classified as the overt-ongoing group (13 patients); patients with previous episodes though not active bleeding, were the overt-previous group (76 patients); and patients with positive fecal occult blood and a decrease in Hb level more than 2 g/dL comprised the occult group (19 patients). Researchers noted that during the study time frame, capsule endoscopy was introduced to the hospital. Therefore 36 of the 108 patients underwent both capsule endoscopy and DBE examinations, though DBE examination in this group, regardless of CE results, focused on the diagnostic precision of DBE for obscure GI bleeding.

Preparation for the DBE examination included a 12-hour overnight fast. Diagnostic biopsies or therapeutic procedures were performed during a DBE as necessary for any lesions discovered. Erosions or red spots that did not bleed during the examination were not considered the bleeding source. All patients were followed-up every two months until the end of the study for a period of at least nine months. The aims of the study investigators were to evaluate the diagnostic yield of DBE for obscure bleeding and assess the impact of DBE on the ultimate diagnosis and treatment plan.

Results

DBE demonstrated a diagnosti
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Contact: Anne Brownsey
abrownsey@asge.org
630-570-5635
American Society for Gastrointestinal Endoscopy
Source:Eurekalert

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