Navigation Links
Study probes genetic link to sickle cell pain management
Date:12/8/2011

AUGUSTA, Ga. A study that may help personalize pain medication management for sickle cell disease patients is underway at Georgia Health Sciences University.

Dr. Cheedy Jaja, a nurse research scientist and Assistant Professor of Biobehavioral Nursing, has received a three-year National Institutes of Health grant to determine if variations in genes known to play a role in metabolizing opioids could help physicians manage sickle cell pain.

The World Health Organization estimates that 275,000 babies are born with sickle cell disease each year. It is most common among African-Americans and people of Hispanic, Mediterranean, Caribbean or Southeast Asian descent.

In the United States, approximately 100,000 people have the disease, including one in four blacks. About 30 percent of patients don't respond well to analgesics prescribed for the debilitating episodic pain that is a hallmark of sickle cell disease.

"They have to go to the emergency department for help," Jaja said. "This core group keeps coming back and coming back."

Health care providers risk misidentifying these patients as drug seekers.

"Sickle cell is a lifelong condition in which a pain crisis can be triggered at any time," Jaja said. "The sad part is that two individuals may have the same disease, but how they experience pain differs vastly. So understanding this difference is critical in understanding how to manage the disease. These are simple questions in sickle cell research that have not been explored."

Ineffective pain management can predispose patients to increased drug tolerance or dependence.

Jaja, who completed a postdoctoral fellowship in pharmocogenetics at Indiana University before obtaining master's degrees in public health genetics and nursing from the University of Washington, had a "what if" moment during his emergency department rotation.

"It could be that the medication they've been given is not
'/>"/>

Contact: Sharron Walls
swalls@georgiahealth.edu
706-721-8605
Georgia Health Sciences University
Source:Eurekalert  

Page: 1 2 3 4

Related medicine news :

1. Despite Treatment, Employees with Depression Generate Higher Absentee Costs, According to Thomson Reuters Study
2. American Council on Exercise (ACE) Study Reveals Kettlebells Provide Powerful Workout in Short Amount of Time
3. TV drama can be more persuasive than news program, study finds
4. Study carried out into biological risks of eating reptiles
5. Neuroimaging study may pave way for effective Alzheimers treatments
6. Study finds racial gaps continue in heart disease awareness
7. Luth Researchs IndicatorEDG(TM) Study Finds Americans Hopes of Achieving Their Dreams Are Fading
8. First blinded study of venous insufficiency prevalence in MS shows promising results
9. Soothing infants with food focus of childhood obesity study
10. People with anxiety disorder less able to regulate response to negative emotions, study shows
11. American Heart Association Rapid Access Journal Report: Study Finds Racial Gaps Continue in Heart Disease Awareness, Low Knowledge of Heart Attack Warning Signs Among Women
Post Your Comments:
*Name:
*Comment:
*Email:
Related Image:
Study probes genetic link to sickle cell pain management
(Date:8/3/2015)... ... August 03, 2015 , ... Novatus, ... contract lifecycle management solution, as well as announced the date of its next ... and ease of contract management tasks as well as enhancements to the customer ...
(Date:8/3/2015)... Pass, OR (PRWEB) , ... August 03, 2015 ... ... Northeast California’s Modoc National Forest, to Ahjumawi Lava Springs, California’s northernmost and among ... of California’s largest untapped ground water aquifers, whose main outflow is at Ahjumawi ...
(Date:8/3/2015)... ... , ... Illinois Health & Science (IHS) has completed the purchase of IBA ... of IBAM NA’s cyclotron sites and research and development facilities. , “We ... well as a large manufacturing hub in Noblesville, Indiana,” said Ken Smithmier, President and ...
(Date:8/3/2015)... ... , ... Foot and Ankle Specialists of the Mid-Atlantic (FASMA) is ... practice in the Mid-Atlantic region – and the second largest in the United States ... , Dr. Hetal Kathrotiya-Mago is a Maryland native. She grew up in Laurel, Maryland. ...
(Date:8/2/2015)... ... August 03, 2015 , ... Career Step, ... exhibiting at the Association for Healthcare Documentation Integrity’s (AHDI) conference being held in ... for the opportunity the AHDI conference provides us to interact with those in ...
Breaking Medicine News(10 mins):Health News:Novatus Unveils Milestone Software Release 2Health News:Medicine Lake Aquifer could ease California drought says fresh water advocate Sharon Kleyne – but is this necessary? 2Health News:Medicine Lake Aquifer could ease California drought says fresh water advocate Sharon Kleyne – but is this necessary? 3Health News:Medicine Lake Aquifer could ease California drought says fresh water advocate Sharon Kleyne – but is this necessary? 4Health News:Illinois Health & Science Expands Nuclear Medicine Footprint With Purchase of IBA Molecular North America, Inc. 2Health News:Leading Foot and Ankle Medical Practice Adds Three New Podiatrists 2Health News:Leading Foot and Ankle Medical Practice Adds Three New Podiatrists 3Health News:Leading Foot and Ankle Medical Practice Adds Three New Podiatrists 4Health News:Career Step to Exhibit at AHDI Conference in Alexandria, Virginia on August 7-8 2
... , WEDNESDAY, Dec. 8 (HealthDay News) -- A new ... blood to scan the genome of a fetus may offer ... genetic diseases, a new study suggests. Currently, a sample ... amniocentesis or chorionic villus sampling, both of which pose a ...
... HealthDay Reporter , WEDNESDAY, Dec. 8 (HealthDay News) -- Allison Glover ... little more than two months after she gave birth to him ... seven weeks early, on Feb. 23, 2000, but both had relatively ... and living in Stone Mountain, Ga. Garrett seemed the ...
... Patients who have complications after colorectal cancer surgery ... is clearly recommended for their diagnosis, a new study ... In addition, patients with complications were more than ... more than 120 days after diagnosis or two months ...
... Learning to read and write are complex processes, which ... known as dyslexia and dysgraphia. Two new studies, published ... ( http://www.sciencedirect.com/science/journal/00109452 ) provide evidence of this variety, ... account. A group of researchers from the Universities ...
... becoming tastier and more appealing to consumers thanks to new ... forms of fiber, which could be a boon to health, ... of Chemical & Engineering News (C&EN), ACS, weekly newsmagazine. ... plays key roles in human health. Fiber creates a feeling ...
... -- Kidney failure patients who are married are more likely ... or widowers or have never married, finds a new study. ... with end-stage kidney failure. Previous research has shown that males, ... more likely than others to receive kidney transplants in the ...
Cached Medicine News:Health News:Mother Talks of the Anger, Confusion and Grief of a SIDS Death 2Health News:Mother Talks of the Anger, Confusion and Grief of a SIDS Death 3Health News:Surgery complications linked to chemotherapy delay, U-M study finds 2Health News:Widening our perceptions of reading and writing difficulties 2Health News:Marital Status May Affect Kidney Transplant Decision 2
(Date:8/3/2015)... , Aug. 3, 2015  Sage Analytics ( ... portable laboratory-quality cannabis potency measurement systems, announced its sponsorship ... Area Cruise Fundraiser. A limited number of tickets are ... and help a great cause while enjoying an open ... cruise around the San Francisco Bay at sunset. ...
(Date:8/3/2015)...  Depomed, Inc. (NASDAQ: DEPO ) ("Depomed" or ... HZNP ) ("Horizon") announcement that it intends to ... a record date to determine the shareholders eligible to ... Board will review the request when it is received. ... the information required under Depomed,s bylaws, the Depomed Board ...
(Date:8/3/2015)... 3, 2015 According to ... Research "Global Market Study on Physiotherapy Equipment - ... Growth by 2022", the global physiotherapy equipment market is estimated ... of 2015 and is expected to grow at ... to account for US$23.7 Bn by 2022. ...
Breaking Medicine Technology:Sage Analytics Sponsors California Cannabis Industry Association Bay Area Cruise FUNdraiser 2Depomed Comments on Horizon Pharma Announcement 2Depomed Comments on Horizon Pharma Announcement 3Depomed Comments on Horizon Pharma Announcement 4Depomed Comments on Horizon Pharma Announcement 5Depomed Comments on Horizon Pharma Announcement 6Global Physiotherapy Equipment Market Will Reach US$ 23.7 Billion by 2022: Persistence Market Research 2Global Physiotherapy Equipment Market Will Reach US$ 23.7 Billion by 2022: Persistence Market Research 3Global Physiotherapy Equipment Market Will Reach US$ 23.7 Billion by 2022: Persistence Market Research 4
... Dec. 9, 2011 /PRNewswire-iReach/ -- Novel Health ... the publication of  2010-2011 market trends study called ,What,s ... The published article is an analysis of sales, pricing, ... specialty biologic products. This study highlights several emerging trends ...
... FRAMINGHAM, Mass. and SYDNEY, Dec. 9, 2011 HeartWare ... HIN), a leading innovator of less invasive, miniaturized circulatory ... heart failure, today announced that CEO Doug Godshall is ... Conference at 10:50 a.m. EST on Wednesday, December 14, ...
Cached Medicine Technology:Biotech Market Trends Study Shows New Competitive Dynamics and Increasing Reimbursement Hurdles 2Biotech Market Trends Study Shows New Competitive Dynamics and Increasing Reimbursement Hurdles 3Biotech Market Trends Study Shows New Competitive Dynamics and Increasing Reimbursement Hurdles 4HeartWare to Present at the Oppenheimer 22nd Annual Healthcare Conference 2
Rad-5v signal extraction pulse oximeter™...
... The WristOx® 3100 is a ... to be worn comfortably on ... monitoring daily activities and for ... of the WristOx is intended ...
... The PulseOx 5500TM is the ... blood oxygen saturation and heart rate ... The PulseOx 5500TM uses SPO Medicals ... device which is more usable for ...
All-in-One Fingertip Oximeter...
Medicine Products: