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Study offers less complex, minimally invasive procedure to treat heart valve leak
Date:9/29/2009

ion for patients with severe mitral regurgitation," said Cliff Kavinsky, MD, study co-investigator and a cardiologist in the Center for Congenital and Structural Heart Disease at Rush. "Instead, we can use a catheter to reach the heart valve."

With a small puncture in the groin area of the leg, a catheter is threaded through the leg vein up into the heart. This allows doctors to manipulate a tiny clip, which can bring the mitral leaflets together to help control or cure the mitral regurgitation and stop the leak.

Because the procedure is minimally invasive, patients usually spend one night in the hospital compared to about five nights with open heart surgery.

Preliminary results from the phase I trial, known as EVEREST I, show that the vast majority of mitral regurgitation patients who had successful results with the MitraClip device did not need mitral valve surgery three years after their procedure and many benefited from significantly improved function of the left ventricle. At 36-months follow-up, 82 percent of patients who had a successful result with the MitraClip device remain free from surgery. Seventy-four percent of patients with one or more clips implanted experienced significant improvement in the leak. Also, 12 months after the procedure, the shape of the left ventricle has improved. This was based on five echocardiographic measures, including left ventricular end-systolic dimension.

"There are no drugs that specifically treat or cure mitral regurgitation," said Hijazi. "This procedure may allow us to stave surgery safely and manage patients' symptoms effectively."


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Contact: Deborah Song
deb_song@rush.edu
312-942-0588
Rush University Medical Center
Source:Eurekalert

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