Navigation Links
Study of 'sarcoid-like' granulomatous pulmonary disease finds elevated rates in WTC responders

Mount Sinai researchers coordinating the largest clinical study to date of "Sarcoid Like" Granulomatous Pulmonary Disease in World Trade Center (WTC) responders have found that the rate of the condition was increased in this group as compared to the records of pre-9/11 FDNY personnel. The study is published online in the American Journal of Industrial Medicine.

The Mount Sinai researchers studied almost 20,000 responders who had an initial exam in the Mount Sinai World Trade Center Medical Monitoring and Treatment Program between July 2002 and September 2007. Overall rates of "Sarcoid Like" Granulomatous Pulmonary Disease were elevated and peaked with an incidence rate of 54 cases per 100,000 between the years 2003 and 2004. Previous studies of pre-9/11 FDNY personnel showed an average yearly rate of 15 cases per 100,000. In addition, patients with the disease had lung function abnormalities consistent with prior studies of WTC responders. Similar findings have also been reported by two other cohort studies, the Fire Department of New York City (Izbicki et al. 2007) and the World Trade Center Registry (Jordan HT et al. 2008).

"More than 50,000 men and women were exposed to products of combustion and particulate matter following the September 11th attacks," said the study's lead author Laura Crowley, MD, Assistant Professor, Preventive Medicine, Mount Sinai School of Medicine.

"Our findings support the hypothesis that environmental exposures generated by the destruction of the World Trade Center may cause 'Sarcoid Like' Granulomatous Pulmonary Disease. The screening and monitoring of all WTC responders, including periodic chest radiography and spirometry, must continue so that the population's medical issues may be optimally addressed by identifying and treating diseases in their earlier stages," she said.

Like sarcoidosis, "Sarcoid Like" Granulomatous Pulmonary Disease appears to be a multisystem disease that causes inflammation in one or more organs, including the lungs, skin and lymph nodes. Although the cause of "Sarcoid Like" Granulomatous Pulmonary Disease is unknown, it has been associated with multiple environmental and occupational exposures.

"The results of this study clearly supports the critical need for ongoing long-term monitoring and treatment for WTC responders," said Philip Landrigan, MD, Principal Investigator of the Mount Sinai WTC Program's Data and Coordination Center, Dean of Global Health and Chair of the Department of Preventive Medicine, Mount Sinai School of Medicine.

"Providing health care for WTC-related illnesses and disease is the least we can do, not only for this study population, but all those whose health has been affected by 9/11. Our 9/11 heroes have given so much in their endeavors to help our country when their labor was required," he said.

The World Trade Center Medical Monitoring and Treatment Program with funding from the federal government, offers free, confidential medical and mental health evaluation, long-term monitoring and treatment for eligible WTC rescue, recovery and clean-up workers, including volunteers, who responded to the Sept. 11th, 2001 terrorist attacks in NYC. Medical screening and annual medical monitoring examinations, as well as both out- and in-patient treatment services as may be needed for WTC-related medical and mental health conditions is being offered at a number of NY/NJ metro-area occupational medicine clinical centers and nationwide. Mount Sinai Center for Occupational & Environmental Medicine, Mount Sinai School of Medicine, has taken a lead in developing the program that stands as the federal government's principal public health response to 9/11 and continues to coordinate the NY-NJ Consortium of occupational medicine providers of program services.

The Program also maintains data through two Data and Coordination Centers, one coordinated by Mount Sinai (School of Medicine) and one by the FDNY, complementing the latter agency's matching service program for current and retired NYC Fire Dept. employees. Non-identifying data is periodically pooled and analyzed across the programs to expand the scientific understanding of health impacts resultant from WTC exposures, assure best practices of care for responders in need, and help inform future health response to such emergencies.

The Program's Mount Sinai-coordinated Consortium of Clinical Centers of Excellence have medically screened over 30,000 WTC rescue and recovery workers and volunteers in all 50 states to date, since the program kicked off in July of 2002. The Consortium has also provided over 66,000 medical monitoring exams.


Contact: Mount Sinai Press Office
The Mount Sinai Hospital / Mount Sinai School of Medicine

Related medicine news :

1. Despite Treatment, Employees with Depression Generate Higher Absentee Costs, According to Thomson Reuters Study
2. American Council on Exercise (ACE) Study Reveals Kettlebells Provide Powerful Workout in Short Amount of Time
3. TV drama can be more persuasive than news program, study finds
4. Study carried out into biological risks of eating reptiles
5. Neuroimaging study may pave way for effective Alzheimers treatments
6. Study finds racial gaps continue in heart disease awareness
7. Luth Researchs IndicatorEDG(TM) Study Finds Americans Hopes of Achieving Their Dreams Are Fading
8. First blinded study of venous insufficiency prevalence in MS shows promising results
9. Soothing infants with food focus of childhood obesity study
10. People with anxiety disorder less able to regulate response to negative emotions, study shows
11. American Heart Association Rapid Access Journal Report: Study Finds Racial Gaps Continue in Heart Disease Awareness, Low Knowledge of Heart Attack Warning Signs Among Women
Post Your Comments:
(Date:10/13/2017)... ... ... The American Board of Family Medicine's (ABFM) Board of Directors has selected Warren ... James C. Puffer upon his retirement. Dr. Newton will serve in the position of ... end of 2018. Upon assuming the role of President and CEO on January 1, ...
(Date:10/13/2017)... ... ... Lori R. Somekh, founder of the Law Office of Somekh & ... and special needs planning attorneys. “Membership in ElderCounsel helps our office remain up to ... with elder law attorneys nationwide,” said Somekh. , ElderCounsel was founded ...
(Date:10/13/2017)... ... October 13, 2017 , ... Ellevate Network, the leading network ... advocate for action towards gender equality at their inaugural Summit in New York City ... and reached a social audience of over 3 million. To watch the Mobilize Women ...
(Date:10/13/2017)... ... October 13, 2017 , ... Coveros, a leader in ... awarded a contract by the Center for Medicare and Medicaid Services (CMS). The ... enterprise use of Agile methodologies in a consistent and high value manner across ...
(Date:10/12/2017)... San Francisco, CA (PRWEB) , ... October 12, ... ... and Dr. Cheng, are now treating sleep apnea using cutting-edge Oventus ... sleep apnea, a serious sleep disorder characterized by frequent cessation in breathing. Oral ...
Breaking Medicine News(10 mins):
(Date:9/19/2017)... 19, 2017   ZirMed Inc ., a recognized leader ... that it has been ranked #1 by its users for ... Rankings 2017 User Survey. ZirMed was recognized as the top-ranked ... and medical centers over 200 beds and holds one of ... user survey history. ...
(Date:9/18/2017)... , Sept. 18, 2017 ... fields of bioinformatics and immune engineering, today ... protective avian influenza A (H7N9) vaccine. ... related to seasonal influenza and presents a ... on prior exposure to be effective. Using ...
(Date:9/12/2017)... YORK , Sept. 12, 2017   EcoVadis , the leading ... has published the first annual edition of its Global CSR Risk and ... companies evaluated by EcoVadis, based on Scorecard Ratings that analyzed nearly 800,000 ... ... Index ...
Breaking Medicine Technology: