Navigation Links
Study of half siblings provides genetic clues to autism
Date:4/17/2012

mothers. Given that half of the risk of transmission was lost and half was preserved among those maternal half siblings, mothers and fathers appear to be transmitting risk equally in families in which autism recurs."

Constantino, the Blanche F. Ittleson Professor of Psychiatry and Pediatrics and director of the William Greenleaf Eliot Division of Child and Adolescent Psychiatry at Washington University and psychiatrist-in-chief at St. Louis Children's Hospital, says the findings also suggest that in many families, the transmission of autism is the result of the effects of many genes not just one with each contributing a small proportion of risk.

Prior estimates of the extent to which autism is influenced by genetic factors are derived from studies of identical and fraternal twins where one, or both, are affected by the disorder. Since identical twins share 100 percent of their genes, and fraternal twins share 50 percent, inherited conditions tend to be twice as common in an identical twin pair compared to a fraternal twin pair. But twin studies of autism are too small to give precise estimates about how the disorder is inherited.

"The largest studies have included less than 300 clinically affected twin pairs," Constantino says. "And they include girls, boys and mixed twin pairs, which complicates the testing of models of inheritance in autism because the disorder is much more common in boys than girls."

Other studies have focused on siblings of children with autism, looking at how much more common autism recurrence is in siblings than the general population. But to derive more information on genetic structure from their family studies, Constantino's group looked at autism recurrence in half siblings and compared it to that in full siblings.

The researchers studied over 5,000 families in which there was a child with autism and at least one additional sibling the families were enrolled in a national volunteer, Internet-
'/>"/>

Contact: Judy Martin
martinju@wustl.edu
314-750-4213
Washington University in St. Louis
Source:Eurekalert

Page: 1 2 3 4 5

Related medicine news :

1. HIV Prevention Pill Cost-Effective for High-Risk Men: Study
2. Avastin No Benefit to Older Lung Cancer Patients: Study
3. Study examines adverse effects among different radiation therapies for prostate cancer
4. Study examines drug regimen for the treatment of non-small cell lung cancer among older patients
5. Kidney cancer patients do better when whole kidney is not removed, U-M study shows
6. Fish Oil Supplements Wont Help in Multiple Sclerosis: Study
7. Study examines medicare use for Mohs micrographic surgery and surgical excision for skin cancer
8. UT MD Anderson study finds cancer related pain often undertreated
9. Tattoos, Piercings Tied to Heavier Drinking in French Study
10. Surgery Rates Rising for Non-Melanoma Skin Cancer: Study
11. Dissolvable Heart Artery Stents Appear Safe in Study
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:9/16/2014)... Recently, BamboofloorChina.com, the popular online supplier of elegant ... strand woven bamboo floors to its product catalogue. ... for the new items; the current discount is up ... great shopping season. Therefore, BamboofloorChina.com spares no energy to ... All practical items offered by BamboofloorChina.com are in stock ...
(Date:9/16/2014)... Marybeth Cale, owner of Cale Communications , a public ... small village of Rhinebeck, New York, has announced the launch ... has expanded the business to incorporate a new scope of ... Those services will include group trainings and workshops on a ... clients all over the country. , Workshops address topics ...
(Date:9/16/2014)... 17, 2014 Operation Smile was founded “on ... of a facial deformity.” To spread their message and mission, ... 2014, at the Beverly Wilshire Hotel in Beverly Hills, California. ... worldwide whose lives have been forever transformed by the efforts ... involved with Operation Smile,” said Lynda Erkiletian, Executive Director of ...
(Date:9/16/2014)... On Friday, September 12, Jusuru International ... an accompanying mobile application, the grand-opening of their ... their sales force, and their sponsorship of the ... national convention, Rise to Enterprise 2014 (R2E14). , ... Regency Orange County was treated to a new ...
(Date:9/16/2014)... September 16, 2014 Pulmonary Hypertension Association Travels ... Education Forum for PH Patients and Families to Help Fight ... – the country’s leading pulmonary hypertension association that works to ... a disease of the lungs that affects the functioning of ... treatment, mean survivability is only 2.8 years. , What:, ...
Breaking Medicine News(10 mins):Health News:BamboofloorChina.com Announces Its Promotion For Strand Woven Bamboo Floors 2Health News:Mompreneur Marybeth Cale of Cale Communications Announces Launch Of Life Coaching And Workshop Business 2Health News:James & Paula Coburn Foundation to Host the 2014 Smile Gala, Presented by Operation Smile 2Health News:New Products Announced at Jusuru International’s R2E14 National Convention 2Health News:New Products Announced at Jusuru International’s R2E14 National Convention 3Health News:New Products Announced at Jusuru International’s R2E14 National Convention 4Health News:Pulmonary Hypertension Association Travels to San Diego for PHA On The Road to Help Fight Rare Lung Disease 2Health News:Pulmonary Hypertension Association Travels to San Diego for PHA On The Road to Help Fight Rare Lung Disease 3
... the House of Commons vote to impose a ban on smoking ... of researchers measured the air quality, using a portable monitor in ... smoking was permitted. The study revealed that the quality of air ... inhaled, would cause harm to the health. ,Dr Richard ...
... An outbreak of cholera was first reported in the Luanda ... nearly 652 cases of cholera// and 22 cholera related deaths ... the latest health report published by the World Health Organization, ... reported over the past 24 hours. 8 municipalities have been ...
... show that about one in 100 11-year-olds had taken a ... one in 10 of 15-year-olds// have taken hard drugs. There ... They take illegal drugs such as cocaine which has created ... The survey was carried out among England's 3.4 million secondary ...
... has developed a technique which uses plastidial transformation which ... from tobacco plants. HSA is an intravenous protein most ... ,It is mainly used to stabilize blood volume ... used for haemorrhages, burns, surgical operations or when the ...
... have joined forces to create an Internet-based training ... postgraduate degrees while continuing to work. ... early March, will create online courses for vets ... science-for-development network. ,African vets urgently need ...
... at the 5th European Breast Cancer Conference (EBCC-5) have called ... and advances made in the field. Doctors and patient groups ... to new drugs like Herceptin that could help prolong their ... in reconstructive surgery and radiation therapy are available to women ...
Cached Medicine News:Health News:Alternate ways to produce HAS from tobacco plants 2
(Date:9/16/2014)... 2014 A study led by St. ... chemotherapy dose threshold below which male childhood cancer survivors ... appears in September 17 edition of the journal ... are at highest risk for reduced sperm production as ... of pre-treatment fertility preservation methods such as sperm banking. ...
(Date:9/16/2014)... Ill. , Sept. 16, 2014 ... new director of Business Communications & Advocacy, Urology ... President, Business Communications & Advocacy Margaret Long. In this ... commitment to urology to patient and advocacy organizations, ... teams on key strategic initiatives. Noland,s appointment is ...
(Date:9/16/2014)... , Sept. 16, 2014 /PRNewswire-iReach/ -- Dan ... GWM Products, LLC, manufacturer of the RTD ® ... plan to expand its sales presence in the U.S. ... hiring and training direct field sales representatives in new ... The company plans to add up to 20 sales ...
Breaking Medicine Technology:Improved risk identification will aid fertility preservation in young male cancer patients 2Improved risk identification will aid fertility preservation in young male cancer patients 3Improved risk identification will aid fertility preservation in young male cancer patients 4Christy Noland to Lead Urology Advocacy and Communications for Astellas 2GWM Products, LLC, announces U.S. market expansion. Dan York added as Director of Sales as part of nationwide growth initiative. 2
... Va., Oct. 30 CEL-SCI Corporation,(Amex: CVM ) ... at the Rodman & Renshaw 9th Annual Healthcare Conference ... 5-7, 2007. The presentation,will be focused on its Phase ... product seeking to become a new first line standard ...
... the Potential ... INDIANAPOLIS and MUMBAI, India, Oct. 30 Eli,Lilly and Company ... into an,agreement with Glenmark Pharmaceuticals S.A. (GPSA) a wholly owned,subsidiary ... agreement, Lilly will acquire the rights to a portfolio of ...
Cached Medicine Technology:CEL-SCI to Present at Rodman & Renshaw 9th Annual Healthcare Conference 2Lilly and Glenmark Pharmaceuticals Announce License Agreement 2Lilly and Glenmark Pharmaceuticals Announce License Agreement 3Lilly and Glenmark Pharmaceuticals Announce License Agreement 4Lilly and Glenmark Pharmaceuticals Announce License Agreement 5
... concave seats and standard-sized backrests with ... seats, backrests, armrests, and casters and ... for the following environments: industry, education, ... care and office. • With tubular ...
... ergonomic chairs with concave seats ... support • Select options like ... and glides. • BTT/1P chairs ... environments: industry, education, laboratory, clean ...
... ergonomic chairs with concave seats ... support • Select options like ... and glides. • BTT/1P chairs ... environments: industry, education, laboratory, clean ...
... chairs with concave seats and large ... options like seats, backrests, armrests, and ... BE Series for top performance in ... education, laboratory, clean room, static control, ...
Medicine Products: