Navigation Links
Study of cell division sheds light on special mechanism in egg cells
Date:8/22/2010

In a study of egg cells using time-lapse microscopy, researchers at the University of California, San Diego School of Medicine and the Ludwig Institute for Cancer Research have discovered an unusual property of meiosis cell division that produces reproductive cells in sexually reproducing organisms. The discovery of an "inside out" mechanism by which egg cell chromosomes separate from each other may shed light on mistakes made in chromosome distribution that can lead to Down syndrome, high miscarriage rates in humans, and the age-related decrease in fertility in human females. Their findings are reported in the September issue of Nature Cell Biology.

Sexual reproduction relies on the merger of chromosomes present in the sperm and egg at fertilization. Formation of sperm and egg cells requires the process of meiosis, which halves the chromosome number of each parent, so that the sperm-egg merger regenerates a cell with two copies of each chromosome. The reduction of chromosome number in meiosis is accomplished through two divisions without an intervening duplication of the genome.

Both meiotic and mitotic divisions require specialized protein polymers called microtubules. These polymers are organized into a football-shaped spindle with the polymer ends embedded in a special organelle called the centrosome at each end of the football. Egg cells, however, are unusual in that they lack centrosomes, and instead use a spindle that is self-organized from microtubules. Egg cells, especially in humans, are prone to mistakes in dividing the chromosomes during meiosis; mistakes which result in reproductive problems in humans such as Down syndrome, infertility and miscarriages.

Researchers led by Arshad Desai, PhD, professor of Cellular and Molecular Medicine and investigator with the Ludwig Institute at UC San Diego, used the roundworm C. elegans, as a model to study egg cell division. Julien Dumont, a postdoctoral fellow in
'/>"/>

Contact: Debra Kain
ddkain@ucsd.edu
619-543-6163
University of California - San Diego
Source:Eurekalert

Page: 1 2

Related medicine news :

1. Pay-for-performance programs improve radiology report turnaround times, study suggests
2. Study Finds Even a Little Cigarette Smoke Harms Airway
3. Virtual colonoscopies help identify additional cancers outside of the colon, study suggests
4. Breast cancer survivors dont need to be afraid of air travel: U of A study
5. New study finds new connection between yoga and mood
6. Study identifies factors which predict alcohol use after liver transplantation
7. Study to examine new treatment for West Nile virus
8. When Doctors Admit Mistakes, Fewer Malpractice Suits Result, Study Says
9. MRSA policies differ among hospitals, study shows
10. Study examines risks, rewards of energy drinks
11. Berkeley study shows ozone and nicotine a bad combination for asthma
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:7/27/2014)... The report, “Glass Fiber & Glass ... Material, By Manufacturing Process, By Application (Transportation, Construction, ... – Global Trends & Forecast to 2019”, defines ... an analysis and forecast by value and volume. ... figures spread through 347 slides and in-depth TOC ...
(Date:7/27/2014)... July 27, 2014 The constant expansion ... increase in demand for enterprise video. Additional factors that ... video in areas such as corporate communication, learning and ... Due to all these factors the enterprise video market ... expected to reach $35.57 billion in 2018 with a ...
(Date:7/27/2014)... 2014 This is a professional ... Dutasteride (CAS 164656-23-9) industry. The report firstly reviews ... its classification, application and manufacturing technology. The report ... Dutasteride (CAS 164656-23-9) listing their product specification, capacity, ... report further analyzes quantitatively 2009-2014 global and China’s ...
(Date:7/27/2014)... 27, 2014 1-Butene is a colorless, ... solvent properties. 1–Butene can be manufactured either through the ... reaction of ethylene. Linear alpha olefin (alkene) 1-Butene is ... a number of important chemicals such as linear light ... on. , The 1-Butene market is extremely competitive. The ...
(Date:7/27/2014)... York, NY (PRWEB) July 27, 2014 ... involving liver injuries continue to move forward in ... new study is questioning one of the benefits ... Tylenol-brand over-the-counter medications. The research, which appears in ... acute low-back pain, all of whom were given ...
Breaking Medicine News(10 mins):Health News:Major Drivers for GFRP Composites Market in Future – Report by MarketsandMarkets 2Health News:Major Drivers for GFRP Composites Market in Future – Report by MarketsandMarkets 3Health News:Major Drivers for GFRP Composites Market in Future – Report by MarketsandMarkets 4Health News:North America Enterprise Video Market is Expected to Reach $13.00 billion in 2018 - New Report by MicroMarket Monitor 2Health News:North America Enterprise Video Market is Expected to Reach $13.00 billion in 2018 - New Report by MicroMarket Monitor 3Health News:North America Enterprise Video Market is Expected to Reach $13.00 billion in 2018 - New Report by MicroMarket Monitor 4Health News:Global and Chinese Dutasteride Industry (CAS 164656-23-9) 2019 Forecasts in New Research Report at ReportsnReports.com 2Health News:Global and Chinese Dutasteride Industry (CAS 164656-23-9) 2019 Forecasts in New Research Report at ReportsnReports.com 3Health News:Global and Chinese Dutasteride Industry (CAS 164656-23-9) 2019 Forecasts in New Research Report at ReportsnReports.com 4Health News:North America 1-Butene Market is Expected to Reach $794 million in 2018 - New Report by MicroMarket Monitor 2Health News:North America 1-Butene Market is Expected to Reach $794 million in 2018 - New Report by MicroMarket Monitor 3Health News:North America 1-Butene Market is Expected to Reach $794 million in 2018 - New Report by MicroMarket Monitor 4Health News:As Tylenol Lawsuits Mount, Bernstein Liebhard LLP Notes Study Questioning Some Benefits Purportedly Associated with Acetaminophen 2Health News:As Tylenol Lawsuits Mount, Bernstein Liebhard LLP Notes Study Questioning Some Benefits Purportedly Associated with Acetaminophen 3Health News:As Tylenol Lawsuits Mount, Bernstein Liebhard LLP Notes Study Questioning Some Benefits Purportedly Associated with Acetaminophen 4
... allows longer filtering, which experts prefer , , THURSDAY, May ... are asleep, not only frees up time during their ... well, a new study suggests. , Although lifesaving, dialysis ... it. Nighttime dialysis, a newer option, actually takes longer ...
... Cambridge, MA May, 21, 2009 Agios Pharmaceuticals, ... novel cancer metabolism drugs, announced that the leading scientific ... "Understanding the Warburg Effect: The Metabolic Requirements of ... C. Cantley, Ph.D., Director of the Cancer Center at ...
... Military ProgramSHORT HILLS, N.J., May 21 The ... organization dedicated to finding cures and treatments for ... people living with paralysis, announced today it has ... charitable giving arm, the TD Charitable Foundation. ...
... Transportation as Legislative Priority for 2009WASHINGTON, May 21 ... the federal transportation bill this year, the American ... for America coalition in releasing a blueprint to ... Route to Reform," outlines a renewed vision for ...
... (Princeton, New Jersey) Lingraphica, maker of the Lingraphica speech-generating ... mobile accessory. Incredibly portable and light, it fits easily ... on the go. Users can take along a selection ... at all times. Together, the Lingraphica speech-generating device and ...
... Department of Veterans Affairs (VA) has provided $215 million ... Veterans in rural and highly rural areas. "This ... health care needs of our rural Veterans," Secretary of ... allow VA to establish new outpatient clinics, expand collaborations ...
Cached Medicine News:Health News:Sleeping Through Dialysis May Be the Way to Go 2Health News:Sleeping Through Dialysis May Be the Way to Go 3Health News:Agios Pharmaceuticals' founders author Science review on cancer metabolism 2Health News:Christopher & Dana Reeve Foundation Receives $25,000 Gift from TD Bank 2Health News:Christopher & Dana Reeve Foundation Receives $25,000 Gift from TD Bank 3Health News:APHA Joins National Coalition in Issuing Transportation Reform Blueprint 2Health News:Secretary Shinseki Announces $215 Million in Projects for Rural Veterans 2
(Date:7/25/2014)... /PRNewswire-iReach/ -- Dr. Michael Gabriel of a prominent ... a recent study, which shows how grief in pregnancy may ... According to US News , ... likely than others to grow up overweight or obese, even ... were two specific types of stress that caused obesity: "Children ...
(Date:7/24/2014)... PLAINFIELD, N.J. , July 24, 2014  PTC ... that the Company will host a webcast conference call ... provide an update on the company,s business and outlook ... before the opening of the market. ... (domestic) or (973) 935-8152 (international) five minutes prior to ...
(Date:7/24/2014)... Germany , and MARSEILLE, France ... , Exclusive global license from University of ... including next-generation sequencing (NGS) gene panels, for blood cancers  ... by new test, indicate favorable prognosis for patients with ... QIAGEN sees potential for developing companion diagnostics to guide ...
Breaking Medicine Technology:Dr. Michael Gabriel of GPM Pediatrics, a Noted Staten Island Pediatrics Clinic, Comments on Study, Which Names Grief as a Cause of Obesity in Children 2QIAGEN Adds Promising Genomic Biomarkers for Assessing Prognosis in Treatment of Blood Cancers to Personalized Healthcare Pipeline 2QIAGEN Adds Promising Genomic Biomarkers for Assessing Prognosis in Treatment of Blood Cancers to Personalized Healthcare Pipeline 3QIAGEN Adds Promising Genomic Biomarkers for Assessing Prognosis in Treatment of Blood Cancers to Personalized Healthcare Pipeline 4QIAGEN Adds Promising Genomic Biomarkers for Assessing Prognosis in Treatment of Blood Cancers to Personalized Healthcare Pipeline 5
... Oct. 28 IRIDEX Corporation (Nasdaq: IRIX ) today ... after the market closes on Thursday, November 4, 2010. ... a conference call with the investment community at 5:00 ... 2010 to discuss the results of the quarter and ...
... SAN DIEGO, Oct. 28 ASTRO Booth # 201 ... will highlight its new TrueBeam™ system for fast, powerful and ... American Society for Radiation Oncology (ASTRO) meeting in San Diego ... as new software capabilities designed to make cancer treatments faster, ...
Cached Medicine Technology:Varian Medical Systems to Exhibit TrueBeam™ System for Image-Guided Cancer Treatments and New Software Capabilities at ASTRO Meeting in San Diego 2Varian Medical Systems to Exhibit TrueBeam™ System for Image-Guided Cancer Treatments and New Software Capabilities at ASTRO Meeting in San Diego 3
Irrigating Cystotome, Straight, 25 g. Overall length 15 mm. 5/box....
Irrigating Capsulorhexis Cystotome. Formed blunt tip, 25 g. Overall length 22 mm. 5/box....
Irrigating Cystotome, formed, 23 g., 12 mm curved tip. Overall length 14 mm. 5/box....
Retrobulbar Needle, 25 g. Atkinson style bevel. Overall length 38 mm. 5/box....
Medicine Products: