Navigation Links
Study of HIV increase in Pakistan could benefit other research

GAINESVILLE, Fla. Rates of HIV have increased in Pakistan's general population, as the virus has spread beyond at-risk groups to women and their children, according to an international team of researchers, including a University of Florida scientist.

The researchers raise concern that the transmission across subgroups into Pakistan's general population may serve as indication that the virus may be spreading into populations within neighboring Afghanistan. The team's epidemiological findings were published in July in the journal PLoS One.

The technique used to understand the forces that drive the HIV epidemic in Pakistan could also help health care professionals understand and intervene in other deadly disease outbreaks wherever they occur, researchers say.

"Are the strains in Pakistan and Afghanistan of two different epidemic origins, or are they the same? It's an important question," said paper author Marco Salemi, a UF College of Medicine professor and a member of the UF Emerging Pathogens Institute and the UF Genetics Institute. "Genetic evidence can be used to test how different populations are intersecting. As you can imagine, behavioral data is difficult to get in some countries and this is why molecular tools are important."

Salemi analyzed DNA sequences of blood samples from three HIV-positive groups: intravenous drug users, men who have sex with men, and women who have become infected by their bisexual spouses. By examining the evolutionary makeup of HIV strains, scientists say one of the strongest factors of the disease's spread is through men who sleep with male intravenous drug users.

The study was led by scientists at Aga Khan University and Dow University of Health Sciences, both in Karachi, Pakistan's capital, and the team is part of a larger consortium of researchers worldwide who have published in the last year, further documenting the spread of HIV in predominantly Muslim countries. The scientists say they will continue the epidemiological work in Afghanistan.

Deriving information from molecular studies is also essential to complement information that may not necessarily be accurate, or truthful, from in-person interviews.

"These questions are very sensitive and most of the behaviors we deal with, even in countries outside the Middle East, are illegal behaviors," said Willi McFarland, director of the HIV Epidemiology Section at the San Francisco Department of Public Health.

McFarland is an author of a PLoS One paper that also appeared this summer. That research was led by scientists from the Qatar branch of Weill Cornell Medical College who examined smaller studies from the Middle East and North Africa of men who hid their sexuality out of fear of prosecution.

Despite certain social and legal limitations that may make conducting similar studies difficult in some parts of the world, McFarland says the trust and confidentiality established between physicians and their patients proved crucial in providing the demographic information needed to conduct international studies such as these.

"Despite the legal consequences, the doctor patient-relationship does seem to be respected," McFarland said.


Contact: Marco Salemi
University of Florida

Related medicine news :

1. Unintended Pregnancies Rising Among Poorer U.S. Women: Study
2. Study: 85 percent of homeless people have chronic health conditions
3. Nurses at Risk for Accidental Exposure to Chemo Drugs: Study
4. Boys Mature Sexually Earlier Than Ever Before: Study
5. Women With Heart Failure Treated as Well as Men: Study
6. Injectable Psoriasis Drugs May Not Hike Heart Risks: Study
7. Mental Illness Affects Women, Men Differently, Study Finds
8. Study: Afghan patients a common source of drug-resistant bacteria
9. Study Links Writing Difficulties to ADHD
10. Most Heart Attack Patients Who Need Angioplasty Quickly Get It: Study
11. Study finds shifting domestic roles for men who lost jobs in current recession
Post Your Comments:
(Date:6/25/2016)... Miami, FL (PRWEB) , ... June 25, 2016 , ... The temporary closing of Bruton ... Plant City Observer , brings up a new, often overlooked aspect of head lice: ... The closing for fumigation is not a common occurrence, but a necessary one in the ...
(Date:6/25/2016)... Long Beach, CA (PRWEB) , ... June 25, 2016 , ... ... from UCLA with Magna Cum Laude and his M.D from the David Geffen School ... San Diego and returned to Los Angeles to complete his fellowship in hematology/oncology at ...
(Date:6/25/2016)... (PRWEB) , ... June 25, 2016 , ... Conventional wisdom ... of success. In terms of the latter, setting the bar too high can result ... more than just slow progress toward their goal. , Research from ...
(Date:6/24/2016)... ... 24, 2016 , ... June 19, 2016 is World Sickle Cell Observance Day. ... the benefits of holistic treatments, Serenity Recovery Center of Marne, Michigan, has ... , Sickle Cell Disease (SCD) is a disorder of the red blood cells, which ...
(Date:6/24/2016)... ... June 24, 2016 , ... Global law firm Greenberg Traurig, ... Elite. The attorneys chosen by their peers for this recognition are considered among the ... Traurig Shareholders received special honors as members of this year’s Legal Elite Hall of ...
Breaking Medicine News(10 mins):
(Date:6/24/2016)... DUBLIN , June 24, 2016 ... and Markets has announced the addition of the ... their offering. ... products and provides an updated review, including its applications ... covering the total market, which includes three main industries: ...
(Date:6/24/2016)... , June 24, 2016 Research and ... Market for Companion Diagnostic Tests" report to their offering. ... for Companion Diagnostics The World Market for ... personalized medicine diagnostics. Market analysis in the report includes the ... Market (In Vitro Diagnostic Kits) by Region (N. America, EU, ...
(Date:6/23/2016)... 23, 2016  MedSource announced today that it ... software solution of choice.  This latest decision demonstrates ... to their clients by offering a state-of-the-art electronic ... establishes nowEDC as the EDC platform of choice ... clients.  "nowEDC has long been a preferred EDC ...
Breaking Medicine Technology: