Navigation Links
Study looks at mitochondrial variation in sperm traits and sperm competitive ability
Date:9/19/2007

RENO, Nev. -- University of Nevada, Reno researchers Jeanne and David Zeh of the Department of Biology have received a five-year, $650,000 grant from the National Science Foundation to investigate the effects of natural mitochondrial variation on sperm traits and sperm competitive ability.

Researchers have found mitochondrial mutations to be one of the primary causes of low sperm count and poor sperm mobility in humans. However, in the field of sexual selection, where maternal inheritance of mitochondria may well have its greatest impact, female-limited response to selection has been largely overlooked. The Zehs study promises to fill in some of this knowledge gap in evaluating the importance of maternal inheritance of mitochondria for sexual selection and male adaptation. Mitochondria are the principal energy source of a cell, and convert nutrients into energy as well as performing many other specialized tasks.

The Zehs study, which will use a neotropical pseudooscorpion Cordylochernes scorpioides as a model system, will encompass whole-genome mitochondrial sequencing, a comprehensive analysis of the physiological and morphological characteristics of sperm that are likely to be important in competitive ability, a large-scale sperm competition experiment designed to identify the target of selection acting on sperm traits, and a replicated, multi-generation experiment in which the evolutionary response to selection on the trait most important in sperm competition will be assessed using both maternally- and paternally-based selection regimes.

Jeanne Zeh, an assistant professor of biology, and David Zeh, an associate professor of biology, both believe that their study will help refine the efforts to understand mitochondrial effects on male fertility.

The fundamental insight that strict maternal inheritance of mitochondria constrains the ability of males to respond adaptively to selection has led to major advances in the study of human male infertility, said Jeanne Zeh, the principal investigator for the study, noting that other studies have also investigated this phenomenon in laboratory mice and domestic fowl. However, these studies have not assessed the effects of natural mitochondrial DNA variation on male fertility and sperm competitive ability.

Clearly, more research is needed, particularly on natural populations not subject to the potentially strong effects of genetic drift associated with domestication.

In addition to their research, the Zehs study also includes an interesting outreach component. They plan on working with a local AP biology teacher who will serve as a graduate research assistant on the project, and they will hold a series of workshops and seminars for other local high school science teachers and students that will promote the importance for society of basic research in ecology and evolution.


'/>"/>

Contact: John Trent
jtrent@unr.edu
775-784-4959
University of Nevada, Reno
Source:Eurekalert

Related medicine news :

1. Rural Canadians travel far for specialists: study
2. A new study surpasses Gene Therapy Hurdle
3. Tomato Sauce reduces Cancer Risk- Study
4. A question on study of Adult Stem Cell
5. Study on obesity and heart failure
6. National Lung Study in the process
7. Marijuana gateway theory strengthened by study of twins
8. Old theory of adaptation confirmed by new study
9. Study casts doubt on keyboard ills
10. Gene study links endometriosis, infertility
11. Study reveals how stress can make you sick
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:5/24/2017)... ... May 24, 2017 , ... Dr. Manju R. Kejriwal, ... ClearCorrect orthodontics, with or without a referral. Dr. Kejriwal understands the emotional and ... convenient, clear braces in Cincinnati, OH. Patients no longer need to feel the esthetic ...
(Date:5/24/2017)... ... May 24, 2017 , ... Dr. Curry Leavitt, a ... (High-Performance Periodontal Practice) continuing education (CE) series. As a compassionate and dedicated clinician, ... by attending numerous CE courses each year. His recent course, Course II of ...
(Date:5/24/2017)... ... May 24, 2017 , ... If you are thinking of a visit to ... business architecture, October is the perfect time to visit. , Business Architecture Associates is pleased ... carte offering for individuals, as a 4-½ day package for individuals, and as 4-½ day ...
(Date:5/24/2017)... ... May 24, 2017 , ... Fiberstar, Inc., http://www.FiberstarIngredients.com ... food and beverage industry offers Citri-Fi®, a natural citrus fiber, to improve beverage ... process. As a result, labels need to deliver simple, transparent and clear messaging. ...
(Date:5/23/2017)... ... May 23, 2017 , ... Axiad IDS , a leading provider ... magazine has named the company a “Top 25 Cybersecurity Companies 2017.” Axiad ... help organizations simply and proactively address potential cybersecurity threats before they happen. The ...
Breaking Medicine News(10 mins):
(Date:5/9/2017)... , May 9, 2017  Demonstrating its ... board of directors for the Pharmaceutical Research and ... for membership. Biopharmaceutical companies will now have to ... order to be eligible to join PhRMA. ... the board is sending a clear message that ...
(Date:5/9/2017)...  Semler Scientific, Inc. (OTCQB: SMLR), an emerging ... the clinical effectiveness and efficiency of healthcare providers, ... ended March 31, 2017. "We ... identify when preventive care options are appropriate, which ... attacks or strokes occur," said Doug Murphy-Chutorian ...
(Date:5/8/2017)... , May 8, 2017  Diplomat Pharmacy, Inc. (NYSE: ... Inc. ("WRB"), a health care service center company ... WRB specializes in relationship management programs for leading ... WRB will join Envoy ... support services for manufacturers, biotech firms, and other service ...
Breaking Medicine Technology: