Navigation Links
Study links acetaminophen to lower prostate cancer risk
Date:5/23/2011

ATLANTA May 23, 2011 A new study from American Cancer Society researchers finds use of 30 tablets a month or more of acetaminophen for five or more years was associated with an estimated 38% lower risk of prostate cancer. The study appears in Cancer Epidemiology, Biomarkers and Prevention and is one of only two studies of prostate cancer to date that have examined the association with acetaminophen use that was both long-term and regular.

Use of aspirin and other nonsteroidal anti-inflammatory drugs (NSAIDs), particularly long-term use, has been associated with modestly reduced risk of prostate cancer in some previous epidemiologic studies. Acetaminophen, a commonly used pain-reliever, is not traditionally considered an NSAID but can have anti-inflammatory effects.

For the current study, researchers led by Eric Jacobs, Ph.D., American Cancer Society epidemiologist, examined the association between acetaminophen use and prostate cancer incidence among 78,485 men in the Cancer Prevention Study II Nutrition Cohort. Information on acetaminophen use was obtained from a questionnaire completed at study enrollment in 1992 and updated using follow-up questionnaires in 1997 and every two years thereafter.

During follow-up from 1992 through 2007, there were 8,092 incident prostate cancer cases identified. Current regular use of acetaminophen (> 30 pills per month) for 5 years or more was associated with lower risk of overall prostate cancer (RR = 0.62, 95% CI 0.44-0.87) as well as lower risk of aggressive prostate cancer (RR = 0.49, 95% CI 0.27-0.88). Current regular use of < 5 years duration was not associated with prostate cancer risk.

"While the results of this observational study suggest that long-term regular acetaminophen use may be associated with lower prostate cancer risk, our findings require replication by other studies, and do not justify use of acetaminophen to prevent prostate cancer. Acetaminophen is considered relatively safe when used at recommended doses but unintentional acetaminophen overdose is an important cause of acute liver failure." said Dr. Jacobs. "Still, results of this study could lead to further research on acetaminophen that might provide biological insights about the process of prostate cancer development and how this process could be slowed."


'/>"/>

Contact: David Sampson
david.sampson@cancer.org
American Cancer Society
Source:Eurekalert

Related medicine news :

1. Despite Treatment, Employees with Depression Generate Higher Absentee Costs, According to Thomson Reuters Study
2. American Council on Exercise (ACE) Study Reveals Kettlebells Provide Powerful Workout in Short Amount of Time
3. TV drama can be more persuasive than news program, study finds
4. Study carried out into biological risks of eating reptiles
5. Neuroimaging study may pave way for effective Alzheimers treatments
6. Study finds racial gaps continue in heart disease awareness
7. Luth Researchs IndicatorEDG(TM) Study Finds Americans Hopes of Achieving Their Dreams Are Fading
8. First blinded study of venous insufficiency prevalence in MS shows promising results
9. Soothing infants with food focus of childhood obesity study
10. People with anxiety disorder less able to regulate response to negative emotions, study shows
11. American Heart Association Rapid Access Journal Report: Study Finds Racial Gaps Continue in Heart Disease Awareness, Low Knowledge of Heart Attack Warning Signs Among Women
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:12/14/2019)... ... 13, 2019 , ... Those seeking a youthful makeover can receive the rejuvenating ... Cosmetic dentistry treatments like BOTOX offer North Charleston, SC patients a more youthful appearance ... of cosmetic dentistry treatments to achieve patients’ smile goals. , “The art of ...
(Date:12/14/2019)... ... December 13, 2019 , ... Intelligent.com, a trusted resource for ... in Child Development Degree Programs for 2020. The comprehensive research guide is based ... program is evaluated based on curriculum quality, graduation rate, reputation, and post-graduate employment. ...
(Date:12/9/2019)... ... December 09, 2019 , ... Representatives with Vigorous Innovations ... for athletes just in time for Christmas. , “We’re very excited about the launched ... and spokesperson for Vigorous Innovations. “The new massage gun can eliminate the fatigue of ...
(Date:12/9/2019)... ... ... WEDI , the nation’s leading nonprofit authority on the use of health ... the U.S. Department of Health and Human Services (HHS), announced today the election of ... as the re-election of ten previous board members to serve two-year terms. , “The ...
(Date:12/9/2019)... Texas (PRWEB) , ... December ... ... global leader in innovative solutions that help food and manufacturing companies engage ... Responsibility training program. This turnkey solution helps manufacturers build a cohesive culture ...
Breaking Medicine News(10 mins):
(Date:12/14/2019)... , ... December 13, 2019 , ... ... suffering from gum disease in Chattanooga, TN receive gentle care through ... their practice, Drs. Felts and Randall provide effective gum disease care without the ...
(Date:12/9/2019)... , ... December 09, 2019 , ... ... optimize healthcare provider savings across purchased services contracts, today announced its latest partnership ... in San Diego County with four acute care hospitals, three specialty hospitals, three ...
(Date:12/8/2019)... ... 2019 , ... Soterius, Inc., an outsourced service provider with ... MAIA Pharmaceuticals, Inc. (MAIA), a specialty pharmaceutical company focused on development and marketing ... Europe, to support their regulatory strategy and operations for filings in Europe. , ...
Breaking Medicine Technology: