Navigation Links
Study in Circulation Research details how diabetes drives atherosclerosis
Date:3/13/2008

Researchers have discovered how diabetes, by driving inflammation and slowing blood flow, dramatically accelerates atherosclerosis, according to research to be published in the March 14 edition of the journal Circulation Research.

Experts once believed that atherosclerosis, or hardening of the arteries, developed when too much cholesterol clogged arteries with fatty deposits called plaques. When blood vessels became completely blocked, heart attacks and strokes occurred. Today most agree that the reaction of the body's immune system to fatty build-up, more than the build-up itself, creates heart attack risk. Immune cells traveling with the blood mistake fatty deposits for intruders, akin to bacteria, home in on them, and attack. This causes inflammation that makes plaques more likely to swell, rupture and cut off blood flow.

Making matters worse, nearly 21 million Americans have diabetes, a disease where patients cells cannot efficiently take in dietary sugar, causing it to build up in the blood. In part because diabetes increases atherosclerosis-related inflammation, diabetic patients are twice as likely to have a heart attack or stroke.

Past work has shown that high blood sugar has two effects on cells lining blood vessels as part of atheroslerosis. First, it increases the production of free radicals, highly reactive molecules that tear about sensitive cell components like DNA, causing premature cell death (apoptosis). This process also reduces the availability of nitric oxide (NO), which would otherwise enable blood vessels to relax and blood flow to increase. In contrast to diabetes, exercise and good diet bring about faster blood flow through blood vessels. The force created by fast, steady blood flow as it drags along blood vessel walls has been shown by recent studies to protect arteries from atherosclerosis. Physical force has emerged recently as a key player in bodily function, capable of kicking off biochemical processes
'/>"/>

Contact: Greg Williams
Greg_Willams@urmc.rochester.edu
University of Rochester Medical Center
Source:Eurekalert

Page: 1 2 3

Related medicine news :

1. Study names 5 factors of social ills in energy, mining and logging communities
2. Avalere Study Shows Medicare Part D Helping People with Type 2 Diabetes; Warns People with Diabetes of Probability of Reaching the Donut Hole
3. Rodent study finds artificial butter chemical harmful to lungs
4. Prescription costs rise more than 6 times when patients reach 65 says study of 5M people
5. Damaged veins heal faster with heparin treatment, laboratory study finds
6. Samarion(SM) Announces Second Outcome Based Study Partner Site for LTC Industrys Only Enterprise Quality Improvement System
7. Echo Therapeutics Announces Positive Results from Symphony(TM) Transdermal Continuous Glucose Monitoring System Study at Tufts Medical Center
8. California Study Offers New Perspective on Relationship Between Staffing Ratios and Patient Safety
9. Study helps explain fundamental process of tumor growth
10. Protein deficiency leads to faster fat burning in mice, study shows
11. Study Finds Naturopathic Care for Chronic Low-Back Pain to be Efficacious, Cost-Effective
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:5/5/2015)... May 05, 2015 With the advent of ... enjoying the feel of warm breezes on bare skin. And ... on how to look their best in shorts, tank tops ... more people are turning to laser treatments for permanent hair ... Simply Posh Aesthetic Spa . “They're all veterans of ...
(Date:5/5/2015)... (PRWEB) May 05, 2015 “We currently have larger ... states Marta Phillips, owner of SunGrubbies.com. “We felt it was ... to find a fashionable sun hat in an extra large size ... event.” , Fashionable derby sun hats such as the ... brim are now available in an extra large size , ...
(Date:5/5/2015)... San Francisco, Calif. (PRWEB) May 05, 2015 ... available online but these have focused primarily on personal ... the National Directory of Insurance (NDOI.com) has ... licensed insurance agents in the U.S. to present their ... public marketplace. , The result is significant and two-fold. ...
(Date:5/5/2015)... No one cares about health problems until they ... Prevention cite multiple sources causing poor indoor air quality ... quality (pollution) can bother your eyes, nose, and throat. It ... cancer.” , Toxic chemicals often get into the human body. ... or in some cases, absorb them through our skin. This ...
(Date:5/4/2015)... Visiopharm, the leader in image analysis for diagnostic ... round of financing with NorthCap Partners . The ... Visiopharm to further accelerate business growth and strengthen their ... diagnostic digital pathology solutions. , "It has been exciting ... solution has energized the pathologists, and how fast we ...
Breaking Medicine News(10 mins):Health News:Laser Hair Removal: Tips for Summertime Grooming 2Health News:Laser Hair Removal: Tips for Summertime Grooming 3Health News:SunGrubbies.com, a Leading Online Retailer of Sun Protection Products, Launches Their New Extra Large Size Fashion Sun Hats Collection 2Health News:NDOI Launch Brings Commercial Insurance Online for the First Time 2Health News:NDOI Launch Brings Commercial Insurance Online for the First Time 3Health News:revitaRUGS is Offering Area Rug Cleaning Discounts in Support of Asthma and Allergy Awareness Month This May 2Health News:revitaRUGS is Offering Area Rug Cleaning Discounts in Support of Asthma and Allergy Awareness Month This May 3Health News:Visiopharm Closes Investment Round to Grow Diagnostic Digital Pathology Business 2Health News:Visiopharm Closes Investment Round to Grow Diagnostic Digital Pathology Business 3
... with Patient Outcome in Neuroblastoma , Expression of ... patients whose tumors lacked CHD5 expression were more likely ... patients whose tumors expressed CHD5. , Neuroblastoma tumors often ... arm of chromosome 1, called 1p36.31. Garrett Brodeur, M.D., ...
... compromised blood, oxygen supply, study suggests , , TUESDAY, June ... name Namenda) may help reduce a form of brain ... Children,s Hospital Boston study. , Hypoxic-ischemia, a compromise ... to cerebral palsy and cognitive/behavioral problems. , In experiments ...
... VIEW, Calif., June 24 MAP,Pharmaceuticals, Inc. ... Telesso,Technologies Limited, formerly Eiffel Technologies Limited ("Eiffel"), ... Pharmaceuticals previously licensed,intellectual property and know-how, as ... to its supercritical fluid technology ("SCF")., ...
... Lack of Provisions for African American,Dialysis Patients, ... Tubbs Jones released this statement regarding the ... 2008. This legislation,prevents the pending 10 percent ... preventive and mental health benefits, improves,and extends ...
... Access To Community,Pharmacies, ALEXANDRIA, Va., June 24 ... 59 in favor of H.R. 6331, which represents ... critical,provisions for community pharmacies that speed up the ... to Medicaid generic,prescription drug reimbursement that would have ...
... LOS ANGELES, June 24 Sport Chalet, Inc.,(Nasdaq: ... opening of its new,50,500 sq. ft. store located at ... now has 52 Sport Chalet locations., A grand ... 27th,through Sunday, June 29th. Activities will include celebrity appearances,sports ...
Cached Medicine News:Health News:Also in the June 24 JNCI 2Health News:Also in the June 24 JNCI 3Health News:Also in the June 24 JNCI 4Health News:Also in the June 24 JNCI 5Health News:Alzheimer's Drug May Reduce Preemie Brain Injury 2Health News:MAP Pharmaceuticals Acquires Proprietary Drug Particle Formulation Technology From Eiffel/Telesso Technologies Limited 2Health News:MAP Pharmaceuticals Acquires Proprietary Drug Particle Formulation Technology From Eiffel/Telesso Technologies Limited 3Health News:Tubbs Jones Supports Medicare Improvements Bill 2Health News:Sport Chalet Opens Store in West Los Angeles 2
(Date:5/4/2015)... 4, 2015  Landauer, Inc. (NYSE: LDR ), ... and monitoring, outsourced medical physics services and high quality ... results for the fiscal second quarter 2015 after the ... The Company will also host a conference call ... p.m. Central Time (5:00 p.m. Eastern Time). Investors may ...
(Date:5/4/2015)... 2015  AcelRx Pharmaceuticals, Inc. (Nasdaq: ACRX ... development and commercialization of innovative therapies for the ... a regulatory update on Zalviso and reported financial ... 2015. Zalviso Regulatory UpdateOn April 21, ... of Anesthesia, Analgesia, and Addiction Products (DAAAP or ...
(Date:5/4/2015)... 4, 2015  Fox Three Partners, LLC ("Fox ... lower middle market, announced today the acquisition of ... and based in Newport News, Virginia ... radiation products for medical professionals as well as ... Capital Partners ("Peninsula"), an investment company specializing in ...
Breaking Medicine Technology:Landauer, Inc. Announces Date And Time For Announcement Of Fiscal Second Quarter 2015 Results And Conference Call 2AcelRx Pharmaceuticals Provides Zalviso Regulatory Update and Reports First Quarter 2015 Financial Results 2AcelRx Pharmaceuticals Provides Zalviso Regulatory Update and Reports First Quarter 2015 Financial Results 3AcelRx Pharmaceuticals Provides Zalviso Regulatory Update and Reports First Quarter 2015 Financial Results 4AcelRx Pharmaceuticals Provides Zalviso Regulatory Update and Reports First Quarter 2015 Financial Results 5AcelRx Pharmaceuticals Provides Zalviso Regulatory Update and Reports First Quarter 2015 Financial Results 6AcelRx Pharmaceuticals Provides Zalviso Regulatory Update and Reports First Quarter 2015 Financial Results 7AcelRx Pharmaceuticals Provides Zalviso Regulatory Update and Reports First Quarter 2015 Financial Results 8Fox Three Partners, LLC Acquires Burlington Medical Supplies, Inc. 2
... 3, 2011 Hologic, Inc. (Hologic or the Company) ... and supplier of premium diagnostics products, medical imaging systems ... of women, today announced that it has appointed Christiana ... Ms. Stamoulis will serve on the Company,s Corporate Development ...
... advances have had a profound effect on how organizations ... evolving communication environment, companies need to continuously adjust their ... challenging, however, to gauge the effectiveness of all the ... internal and external communication options. In ...
Cached Medicine Technology:Hologic Announces Appointment of New Director 2Internal and External Communication Insights: Effective Approaches for Reaching Clients and Co-Workers 2
Extremely wide blade opening. Excellent bio and MRI compatibility. Lot number on each clip. Long reliable history. Standard type 1/1 (mm), opening width 9.0 mm and length 8 mm....
Extremely wide blade opening. Excellent bio and MRI compatibility. Lot number on each clip. Long reliable history. Large type 1/1 (mm), opening width 19.0 mm and length 21 mm....
The Vitek 2 is a fully automated bacteriology system that performs bacterial identification and susceptibility testing analysis using a standard inoculum. It detects resistance and helps combat bacte...
IDS Rapid STR, a microbial identification system....
Medicine Products: