Navigation Links
Study in 7,000 men and women ties obesity, inflammatory proteins to heart failure risk
Date:5/1/2008

Heart specialists at Johns Hopkins and elsewhere report what is believed to be the first wide-scale evidence linking severe overweight to prolonged inflammation of heart tissue and the subsequent damage leading to failure of the bodys blood-pumping organ.

The latest findings from the Multiethnic Study of Atherosclerosis (MESA), to be published in the May 6 issue of the Journal of the American College of Cardiology, appear to nail down yet one more reason for the estimated 72 million obese American adults to be concerned about their health, say scientists who conducted the research.

The biological effects of obesity on the heart are quite profound, says senior study investigator Joo Lima, M.D. Even if obese people feel otherwise healthy, there are measurable and early chemical signs of damage to their heart, beyond the well-known implications for diabetes and high blood pressure.

He adds that there is now even more reason for them to lose weight, increase their physical activity and improve their eating habits.

In the latest study, researchers conducted tests and tracked the development of heart failure in an ethnically diverse group of nearly 7,000 men and women, age 45 to 84, who were enrolled in the MESA study, starting in 2000.

Of the 79 who have developed congestive heart failure so far, 35 (44 percent) were physically obese, having a body mass index, or BMI, of 30 or greater. And on average, obese participants were found to have higher blood levels of interleukin 6, C-reactive protein and fibrinogen, key immune system proteins involved in inflammation, than non-obese adults.

A near doubling of average interleukin 6 levels alone accounted for an 84 percent greater risk of developing heart failure in the study population.

The researchers from five universities across the United States also found alarming links between inflammation and the dangerous mix of heart disease risk factors known as
'/>"/>

Contact: David March
dmarch1@jhmi.edu
410-955-1534
Johns Hopkins Medical Institutions
Source:Eurekalert

Page: 1 2 3

Related medicine news :

1. High blood pressure still sneaking past doctors, Stanford study shows
2. Study by Texas A&M University-Corpus Christi Confirms Training With Vision Software Enhances Hitting Skills
3. Canary Foundation and the National Cancer Institute Launch New Prostate Cancer Study
4. Largest study to date finds benefits of ICDs in children
5. Study shows power of police and fire officers as injury-prevention messengers
6. Study raises questions about prostate cancer therapies targeting IGF-1
7. Children More Vulnerable to Harmful Effects of Lead at Age 6 Than as Toddlers, Says New Study
8. Flip Flops, Mulch and No Coat: Study Identifies Surprising Barriers to Outdoor Activity for Kids in Child-Care Centers
9. Penn study finds elderly heart patients with ICD devices live longer after heart failure
10. Physical activity, healthy eating and BMI not linked in older teens: study
11. Salk study links diabetes and Alzheimers disease
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:8/30/2014)... August 30, 2014 “In 2013, a vehicle ... Jones Firm says in a recently released article on ... was injured in an auto accident every 12 minutes, and ... they continue. “Based on the 2013 statistics, between now and ... collision.” , The threat of an auto accident is real ...
(Date:8/30/2014)... MA (PRWEB) August 30, 2014 Barton ... nurse practitioner locum tenens company , announces a ... September 1, 2014. Barton Associates is headquartered in Peabody, ... CT; Keene, NH; and Jupiter, FL. , ... to the increasing demand for healthcare providers. The United ...
(Date:8/30/2014)... 2014: The first multidisciplinary recommendations on the management ... (ACS) are published today in EP Europace ... by the European Heart Rhythm Association (EHRA), the ... Association of Percutaneous Cardiovascular Interventions (EAPCI), all of ... chairperson of the task force, said: "Sudden cardiac ...
(Date:8/30/2014)... Saturday 30 August 2014: The therapeutic benefit ... emphasised in the 2014 ESC/EACTS revascularisation guidelines presented ... Professor Stephan Windecker (Switzerland) of the European Society ... of the European Association for Cardio-Thoracic Surgery (EACTS). ... European Heart Journal (1), on the ...
(Date:8/29/2014)... (PRWEB) August 30, 2014 AGH Healthy ... the Doctors in Delaware at Atlantic General ... free health-related services. In addition to no-cost blood pressure ... offers first aid care at local sports tournaments. ... other medical staff provide free disease management and falls ...
Breaking Medicine News(10 mins):Health News:Startling Washington Auto Accident Statistics Discussed In Recently Released Article By The Jones Firm 2Health News:Barton Associates Announces New Office Location in Austin, TX 2Health News:First multidisciplinary recommendations on management of arrhythmias in ACS patients 2Health News:ESC/EACTS revascularization guidelines stress benefit of revascularization in stable CAD 2Health News:ESC/EACTS revascularization guidelines stress benefit of revascularization in stable CAD 3Health News:Doctors in Delaware from Atlantic General Hospital Offer No-Cost Services to Area Residents 2Health News:Doctors in Delaware from Atlantic General Hospital Offer No-Cost Services to Area Residents 3
... The pharmaceutical industry is a "market for lemons," a ... buyer about the product and can profit from selling products ... believe, according to an analysis that will be presented at ... "Sometimes drug companies hide or downplay information about serious side ...
... study shows the impact of alcohol intoxication on reasoning ... feel they have recovered enough to drive after drinking. ... president of research for Lifespan, is the first to ... rising and declining blood alcohol concentrations, at matched blood ...
... , TUESDAY, Aug. 17 (HealthDay News) -- Nearly 40 percent ... episodes of manic behavior, a new study suggests. Researchers ... that these patients have what,s called "subthreshold hypomania" -- meaning ... days, and is therefore below the threshold for bipolar disorder. ...
... Community Living Assistance Services and Supports (CLASS) Act a ... Care Act has the potential to transform long-term care ... insurance-based system, according to the latest issue of ... With funding from The SCAN Foundation , this ...
... for airway repair in the lung but that persist in ... poor prognosis in patients who develop cancer, even those with ... have found. These adult stem cells are found in ... areas, suggesting that these cells may mutate and become cancer ...
... an Aging America" will be the focus of the 24th ... Aging from 8 a.m. to 3:30 p.m. Wednesday, Sept. 8 ... The conference, sponsored by The University of Texas Health ... Aging, will include panel discussions, a keynote address by Robert ...
Cached Medicine News:Health News:Pharmaceuticals: A market for producing 'lemons' and serious harm 2Health News:Pharmaceuticals: A market for producing 'lemons' and serious harm 3Health News:Why drunk drivers may get behind the wheel 2Health News:Why drunk drivers may get behind the wheel 3Health News:Many Depressed People Have Mild, Brief Episodes of Mania 2Health News:CLASS Act analysis reveals America's long-term care future 2Health News:Lung stem cells vital to lung repair associated with poor cancer prognosis when found in tumor 2
(Date:8/29/2014)... Research and Markets has announced ... Forecast of Pharmaceutical Equipment Market in China, 2014-2018" ... Development Trend Forecast of Pharmaceutical Equipment Market in ... China,s pharmaceutical equipment industry in the aspects ... and business performance of domestic major enterprises, as well ...
(Date:8/29/2014)... 2014 According to the ... Services (Equipment, Reagent, Primer, Probe, Custom Oligos), End-User ... Gene Synthesis, NGS, DNA, RNAi) - Global Forecast ... Synthesis Market is expected to reach $1,712.1 Million ... at a CAGR of 9.8% from 2014 to ...
(Date:8/29/2014)... 2014 /PRNewswire-iReach/ -- ChemImage will present a workshop focused ... Zealand Forensic Science Society,s 22 nd International ... Adelaide, Australia .  Forensic Scientists will be ... hyperspectral imaging can bring to examination procedures. ... of Product Development at ChemImage, will host a ...
Breaking Medicine Technology:Research and Development Trend Forecast of Pharmaceutical Equipment Market in China, 2014-2018 2Oligonucleotide Synthesis Market Worth $1,712.1 Million by 2019 2Oligonucleotide Synthesis Market Worth $1,712.1 Million by 2019 3Oligonucleotide Synthesis Market Worth $1,712.1 Million by 2019 4ChemImage to Discuss Hyperspectral Imaging for Forensic Investigation at the ANZFSS 22nd International Symposium on the Forensic Sciences 2ChemImage to Discuss Hyperspectral Imaging for Forensic Investigation at the ANZFSS 22nd International Symposium on the Forensic Sciences 3
... The Professional Gold Package is ... laboratory. The package includes the ... automated system, starter package accessory ... adapter, specimen mounts 1/2" head, ...
... Semi-Automatic Tissue Sectioning System has maintained the ... system. Researchers from around the globe have ... their fresh and fresh fixed tissue sectioning ... With the Vibratome Automatic Tissue Sectioning Systems, ...
... Plus Sectioning System provides a versatile means ... plant tissues. The 1000 employs a ... freezing or embedding. The creation of ... of enzyme activities, and other deleterious effects ...
... with a square vice mounting device. ... for mounting specimens and placing in ... blocks are annodized black for easy ... They are shipped three to ...
Medicine Products: