Navigation Links
Study identifies which men are likely to have persistent prostate cancer
Date:2/14/2008

A new Fox Chase Cancer Center study suggests a biopsy reveals more important information about a mans prostate cancer than previously understood. Doctors hope the new findings will help them tailor radiation treatment.

Radiotherapy offers the chance of a cure for most patients, explained Mark K. Buyyounouski, M.D., M.S., attending physician in the radiation oncology department at Fox Chase Cancer Center. For some, however, an elevated PSA level after treatment indicates the cancer is still around or has come back. Our new study shows how we can use biopsy information prior to treatment to help us predict which patients are most likely to still have disease after treatment. With this knowledge, we can better tailor treatment.

In the study presented by Buyyounouski today at the 2008 Genitourinary Cancers Symposium in San Francisco, researchers compared prostate biopsies taken before treatment with those taken again two years after treatment. All the study volunteers had cancers that were classified as intermediate or high risk.

Larger tumors are believed to be more likely to persist after treatment, but what defines a larger tumor has been controversial, said Buyyounouski. What we found was that a high percentage of cancer observed in the biopsy taken before treatment correlated with a higher probability of a positive biopsy after treatment. This information is important because locally persistent prostate cancer may result in laterspread of the disease and possibly death.

Buyyounouski explained that other researchers have explored the use of biopsy information to identify higher risk of recurrence for men with prostate cancer. Using a percentage of positive biopsy cores has been advocated by some, but these types of studies compared the cores to PSA level after treatment and not post-treatment biopsies.

This study is important because the percentage of cancer seen in the biopsy before treatment is directly correlated with cancer seen in the biopsy in the same location two years after treatment, explained Buyyounouski.

We believe this study will help raise awareness about which patients may be at greatest risk of having persistent prostate cancer and help us improve future treatment.

Buyyounouski said current sophisticated radiation technologies such as IMRT could allow physicians to tailor treatment for these patients.

Our next step in this area of research is to see if we can prevent recurrence by delivering more radiation to the area of the prostate with the greatest amount of cancer.


'/>"/>

Contact: Karen Mallet
karen.mallet@fccc.edu
414-312-7085
Fox Chase Cancer Center
Source:Eurekalert

Related medicine news :

1. Penn study finds pro-death proteins required to regulate healthy immune function
2. New study shows promise in reducing surgical risks associated with surgical bleeding
3. Study, meta-analysis examine factors associated with death from heatstroke
4. Study suggests loss of 2 types of neurons -- not just 1 -- triggers Parkinsons symptoms
5. Study says COPD testing is not measuring up
6. Preclinical study suggests organ-transplant drug may aid in lupus fight
7. Ability to cope with stress can increase good cholesterol in older white men, study finds
8. High alcohol consumption increases stroke risk, Tulane study says
9. Mailman School of Public Health study examines link between racial discrimination and substance use
10. Pitt study finds inequality in tobacco advertising
11. Stanford study highlights cost-effective method of lowering heart disease risks
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:10/13/2017)... ... ... “The Journey: From the Mountains to the Mission Field”: the story of a missionary ... Journey: From the Mountains to the Mission Field” is the creation of published author, ... ages and currently teaches a class of ladies at her church, which she has ...
(Date:10/12/2017)... ... , ... Planet Fitness, one of the largest and fastest growing franchisors and ... flagship location in Covington, LA at 401 N. U.S. Highway 190, in January of ... Depot in the Holiday Square shopping center. Its location allows it to serve both ...
(Date:10/12/2017)... ... October 12, 2017 , ... Asante, ... post-acute health care, have expanded their existing home health joint venture through an ... has been operating a joint venture home health company with Asante, delivering clinically ...
(Date:10/12/2017)... ... ... Leading pediatric oncology experts at Children’s National Health System will join ... International Society of Paediatric Oncology (SIOP) Oct. 12-15. Chaired by Jeffrey Dome, ... at Children’s National, and Stephen P. Hunger, M.D., Chief of the Division of ...
(Date:10/12/2017)... ... October 12, 2017 , ... ... in property taxes a year. In some states—like New York, New Jersey, Massachusetts, ... contrast, many overseas retirement havens have extremely low property-tax rates, which contributes to ...
Breaking Medicine News(10 mins):
(Date:9/19/2017)... 2017   ZirMed Inc ., a recognized leader in ... it has been ranked #1 by its users for the ... 2017 User Survey. ZirMed was recognized as the top-ranked end-to-end ... medical centers over 200 beds and holds one of the ... survey history. ...
(Date:9/18/2017)... 2017 EpiVax, Inc. ("EpiVax") a ... immune engineering, today announced a new NIH-funded ... ... and presents a challenge for traditional flu ... be effective. Using state-of-the-art bioinformatics and molecular modeling methods, ...
(Date:9/12/2017)... 12, 2017   EcoVadis , the leading platform for environmental, social ... annual edition of its Global CSR Risk and Performance Index. The report ... based on Scorecard Ratings that analyzed nearly 800,000 data points across the ... ... ...
Breaking Medicine Technology: