Navigation Links
Study identifies factors linked with better medication response for treatment of juvenile arthritis
Date:11/6/2011

o received biologic agents. All biologically naive (had not previously received a biological agent) patients who started etanercept before October 2009 were included, with follow-up data to January 2011. Among the 262 patients, 185 (71 percent) were female, 46 (18 percent) had systemic-onset and the median (midpoint) age at initiation of etanercept treatment was 12.4 years.

For this study, response to treatment was evaluated 15 months after initiation of etanercept. Excellent response was defined as inactive disease or discontinuation earlier due to disease remission; intermediate response: more than 50 percent improvement from baseline, but no inactive disease; and poor response: less than 50 percent improvement from baseline or discontinuation earlier due to ineffectiveness or intolerance.

Of the 262 patients, 85 (32 percent) were considered excellent responders after 15 months of treatment; a total of 85 patients (32 percent) were considered poor responders; and the remaining 92 patients were considered intermediate responders. Compared with achieving an intermediate or poor response, achievement of an excellent response was associated with lower scores on measures of disability at study entry; low number of DMARDs (including methotrexate) used before introduction of etanercept; and younger age at onset. Compared with achieving an intermediate or excellent response, achievement of a poor response was associated with systemic JIA and female sex.

Within the first 15 months of treatment, 119 patients experienced 1 or more adverse events (infectious, noninfectious, or serious; including 37 patients with an excellent response, 36 with an intermediate response, and 46 with a poor response) and 53 patients reported at least 1 infectious adverse event or an infectious serious adverse event. Sixty-one patients discontinued etanercept treatment within the first 15 months of treatment, including 4 with an excellent response, 0 with an intermediat
'/>"/>

Contact: Marieke H. Otten, M.D., M.Sc.
m.otten@erasmusmc.nl
JAMA and Archives Journals
Source:Eurekalert

Page: 1 2 3

Related medicine news :

1. Food Challenges Provide Best Allergy Diagnoses: Study
2. Pregnancy Safe for Most Women With Lupus: Study
3. Mayo Clinic study finds CT scans can help detect gout cases traditional tests miss
4. Common Breast Cancer Gene Test May Be Flawed, Study Says
5. Buyer, Beware of Over-the-Counter Thyroid Supplements: Study
6. New study from NYUCN is the first to look at nursing error disclosure in nursing homes
7. Brain Stimulation May Help Kill Cigarette Cravings, Study Finds
8. Too Much Sitting Raises Odds for Cancer: Study
9. Study Finds No Link Between Dyslexia and IQ
10. Study identifies an expanded role for PKM2 in helping cancer cells survive
11. Latex gloves lead to lax hand hygiene in hospitals, study finds
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:8/30/2014)... After offering hyperbaric oxygen therapy ... past several years, Dr. Roy Schmidt and the ... a scholarship program for veterans who have been ... held this summer to discuss veterans’ needs ( ... shed light on the large number of veterans ...
(Date:8/30/2014)... Seniors Guide, the comprehensive guide to all things senior, ... Disease, Dementia, and Memory Loss . , Country singer Glen ... with the Alzheimer’s, inspired Seniors Guide writers to review the ... movie, out on October 14, 2014, shows a glimpse of ... disease – which inspires a final tour from the musician ...
(Date:8/30/2014)... August 30, 2014 Continuing to meet ... is expanding with the addition of a new doctor ... who has provided leading-edge skin care in Grand Rapids ... , “As a doctor, my passion is making ... partnering with Forefront Dermatology, I’m better able to focus ...
(Date:8/30/2014)... August 30, 2014 Hastings and Hastings, ... attorneys located throughout Arizona is pleased to report having ... one specific example among many cases where Hastings and ... able to retain a greater portion of their settlement ... that providing a positive solution for Arizona car accident ...
(Date:8/30/2014)... Texas (PRWEB) August 30, 2014 ... Oven Industry, 2009-2019 is a professional and in-depth ... industry. The report firstly reviews the basic information ... manufacturing technology. The report then explores global and ... product specification, capacity, production value, and market share ...
Breaking Medicine News(10 mins):Health News:Tennessee Hyperbaric Center Offering HBOT Scholarships to Veterans 2Health News:Alzheimer’s Disease and Dementia Focus on Retirement Website SeniorsGuideOnline.com 2Health News:Expanding Care at the Forefront of Dermatology 2Health News:Hastings and Hastings Is Pleased To Report Having Saved A Client $67,100 On A Settlement Of $610,000 2Health News:Lab Oven Industry for Global and Chinese Market Forecasts to 2019 in New Research Report Available at ReportsnReports.com 2Health News:Lab Oven Industry for Global and Chinese Market Forecasts to 2019 in New Research Report Available at ReportsnReports.com 3Health News:Lab Oven Industry for Global and Chinese Market Forecasts to 2019 in New Research Report Available at ReportsnReports.com 4
... PORTLAND, Ore Newly-published research by scientists at Oregon ... intake is not enough to promote significant weight loss. ... mechanism that reduces a person,s physical activity in response ... in the April edition of the American Journal ...
... will present several studies at the American Academy of ... for the treatment of multiple sclerosis (MS) and surprising ... meeting will take place April 10-17 in Toronto. , ... for 6 Months in Patients with Relapsing Multiple Sclerosis: ...
... Athletic ... , ... Brook, IL (Vocus) -- AthletiCo Physical and Occupational Therapy recently supported the ... Month) in March. The theme of this year’s NATA Month was ‘Sport Safety is ...
... cells to damaged heart tissue , TUESDAY, April 13 (HealthDay ... cells to damaged areas of animal hearts. , The strategy ... retain the cells, potentially boosting the power of cardiac stem ... a treatment for heart injuries, but 24 hours after infusion, ...
... ... OxySure has been named as a finalist in the Health category for its ... Awards recognize new companies that will have a significant impact on the environment, ... used to raise funds to support business incubation programs for technology-based entrepreneurs. ...
... note that many taking them already face higher risk ... Some anticonvulsants used to treat epilepsy and other conditions ... violent death, a new study finds. , While these ... are also approved treatments for other conditions, such as ...
Cached Medicine News:Health News:Diet alone will not likely lead to significant weight loss 2Health News:Groundbreaking MS research to be presented at American Academy of Neurology Annual Meeting 2Health News:Groundbreaking MS research to be presented at American Academy of Neurology Annual Meeting 3Health News:Athletico Raises $6,500 For Chicago Hornets Sled Hockey Team 2Health News:Athletico Raises $6,500 For Chicago Hornets Sled Hockey Team 3Health News:Magnets Might Boost Stem Cell Therapy 2Health News:OxySure Systems, Inc. Named Tech Fort Worth IMPACT Awards Finalist 2Health News:OxySure Systems, Inc. Named Tech Fort Worth IMPACT Awards Finalist 3Health News:Study Shows Some Anti-Seizure Meds Raise Suicide Risk 2Health News:Study Shows Some Anti-Seizure Meds Raise Suicide Risk 3
(Date:8/29/2014)... Calif. , Aug. 29, 2014 Thoratec ... in device-based mechanical circulatory support therapies to save, support ... participating in the 2014 Morgan Stanley Global Healthcare Conference ... Burbach , President and Chief Executive Officer, will provide ... Eastern Daylight Time (9:55 a.m., Pacific Daylight Time).   ...
(Date:8/29/2014)... DUBLIN , Aug. 29, 2014 ... the "Global Peptide Cancer Therapeutics Market & Pipeline ... The conventional methods developed to prevent and eradicate ... cancer treatment. These methods are confined to low specificity, ... the researchers to look for a better solution. It ...
(Date:8/29/2014)... -- Does your doctor know what you,re smoking?  Chances are, ... to the over 112,000 currently registered patients under ... other roughly 20,300+ active physicians listed with the Colorado Dept ... even though a poll in February 2014 showed 51% of ... it. "With marijuana legalization underway, every doctor ...
Breaking Medicine Technology:Global Peptide Cancer Therapeutics Market & Pipeline Insight 2014 2Medical Rules Marijuana Sales in Colorado But Most Doctors Still in the Dark 2Medical Rules Marijuana Sales in Colorado But Most Doctors Still in the Dark 3Medical Rules Marijuana Sales in Colorado But Most Doctors Still in the Dark 4
... EAST HANOVER, N.J., April 8, 2011 Unity ... "Company") is a Health Resource Company specializing in ... Software and Technologies, along with Pharmacy Instrumentation, Calibration, ... Management Group, Inc. ("UNITY") (OTCMARKETS: UYMG) announced today ...
... IRVING, Texas, April 8, 2011 Novation, the leading ... of St. Jude Medical (St. Paul, MN) to its ... St. Jude Medical is a leading provider ... pain patients. The company provides a full portfolio of ...
Cached Medicine Technology:Unity Management Group, Inc. MCC Receives First Major Order for B&D Italia Tablet Press 2Unity Management Group, Inc. MCC Receives First Major Order for B&D Italia Tablet Press 3Novation Announces the Addition of St. Jude Medical to the Cardiac Rhythm Management Products Portfolio 2
... reference laboratory and a worldwide leader in ... an extensive test menu of highly complex ... anatomic pathology. Owned by the University of ... half of the nation's university teaching hospitals ...
... is a national reference laboratory and a ... development. ARUP offers an extensive test menu ... in clinical and anatomic pathology. Owned by ... include more than half of the nation's ...
... ARUP Laboratories is a national reference laboratory ... research and development. ARUP offers an extensive ... medical tests in clinical and anatomic pathology. ... Laboratories' clients include more than half of ...
... reference laboratory and a worldwide leader in ... an extensive test menu of highly complex ... anatomic pathology. Owned by the University of ... half of the nation's university teaching hospitals ...
Medicine Products: