Navigation Links
Study finds vaccine extends recurrent GBM survival rates by 2 to 3 times
Date:6/3/2011

nitiated within 5 weeks post-surgery and consisted of 25 g HSPPC-96, given ID weekly x 4, followed by bi-weekly injections for up to 52 weeks. Results: A total of 33 patients at first recurrence (M:F = 25:8) with a median KPS of 80 were entered. A median of 6 injections (range: 1-15) were administered to the ITT population, with a requisite of 4 vaccinations for the evaluable population. The vaccine was well tolerated with no attributed serious adverse events and no related grade 3 or 4 toxicities. Injection site reaction was seen in 12 patients and fatigue was reported in 9 patients. As of Jan. 2011, the median survival (KM estimates) is 324 days for ITT population (37-877) and 333 days for evaluable population (99-877). 11 patients are still alive and being followed, including 4 beyond one year (374d, 419d, 578d, and 877 days, respectively). All patients with immunological endpoints tested to date exhibited a significant innate immune response and all patients demonstrated CD8 T cell IFN gamma production upon restimulation with autologous gp-96; following vaccine administration. Conclusions: HSPPC-96 evokes a specific and innate immune response in patients with recurrent glioma and survival data available to date indicates HSPPC-96 vaccine provides a possible clinical benefit with a favorable safety profile. Collectively these results provide the impetus for Phase 3 testing against currently approved therapies for patients with recurrent glioblastoma.


Cynthia Owusu, MD, MS
Title: The trajectory of physical functioning during breast cancer treatment of older women.

Saturday June 4, 2:00 PM to 6:00 PM

Abstract (http://abstract.asco.org/AbstView_102_81152.html): Background: We sought to characterize the trajectory of physical functioning during the first 12 months following initial breast cancer diagnosis in older women with stage I-
'/>"/>

Contact: Alicia Reale
alicia.reale@uhhospitals.org
216-533-0685
University Hospitals Case Medical Center
Source:Eurekalert

Page: 1 2 3 4 5 6 7 8 9 10 11 12

Related medicine news :

1. BUSM study finds older men more likely to lose the ability to orgasm due to gabapentin
2. Obesity Greater Risk for Fatty Liver Than Alcohol, Study Finds
3. Safer sex: Study examines sexual communication in transgender community
4. High-Risk Surgeries Getting Safer: Study
5. Study: Children of divorce lag behind peers in math and social skills
6. New grant to study how pediatric brain tumor, ependymoma, develops
7. USC study locates the source of key brain function
8. Penn study identifies genes that may help predict response to BRAF inhibitors for advanced melanoma
9. Children With ADHD More Prone to Substance Abuse: Study
10. Study finds fire stations contaminated with MRSA
11. New study looks at disconnect between medical and lay expertise
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:8/28/2014)... working out how to safely increase the radiotherapy dose ... local control and survival. , Standard treatment for locally ... radiotherapy and chemotherapy. Traditionally this is planned in a ... be enough to stop tumour growth. , The potential ... varies between patients and depends on the size and ...
(Date:8/28/2014)... New York (PRWEB) August 28, 2014 ... currently perceived with great interest among other healthcare industry ... to the high demand in vaccine with respect to ... highly in demand due to an improved understanding for ... across the United States. It has led to new ...
(Date:8/28/2014)... AmeriPride Services, a leading textile services and ... of its new Customer Portal, an online resource that ... convenient for customers. The industry-leading digital tool allows customers ... the company. , Features of the new customer portal ... download and pay bills online , View ...
(Date:8/28/2014)... 28, 2014 After more than two ... is excited to announce the opening of Houston’s ... in any city, Mirror Mirror Beauty Boutique offers premium ... on the corner of Richmond and Drexel near Highland ... amenities, and cutting-edge technology in a private, easy to ...
(Date:8/28/2014)... August 28, 2014 Hastings and Hastings ... been providing quality accident attorney services and other legal ... is proud to announce that it has saved a ... has been valued at over half of a million ... provides genuine discount attorney's fees that result in real ...
Breaking Medicine News(10 mins):Health News:Research demonstrates potential method to better control lung cancer using radiotherapy 2Health News:U.S. Vaccine Market: Opportunities and Threats by Transparency Market Research 2Health News:U.S. Vaccine Market: Opportunities and Threats by Transparency Market Research 3Health News:AmeriPride Services Launches New Customer Portal 2Health News:AmeriPride Services Launches New Customer Portal 3Health News:Mirror Mirror Beauty Boutique to Welcome Its First Patients 2Health News:Hastings and Hastings Is Pleased To Report Having Saved A Client $23,400 On Settlement Of $540,000 2Health News:Hastings and Hastings Is Pleased To Report Having Saved A Client $23,400 On Settlement Of $540,000 3
... ... bring together leaders in open innovation , ... Washington, DC (Vocus) -- This Friday, Prize4Life will be an ... session jointly hosted by the White House Office on Science and Technology Policy, the ...
... ... ... version of Greenpeace’s Cool IT Leaderboard (1) reveals how some global IT companies are leading ... energy use, while others seem unable to decide if IT climate solutions are a significant ...
... also at higher risk for cardiac events, research shows ... with erectile dysfunction, those who also have low testosterone levels ... disease, a new study has found. , In a ... link between obesity and impairment of blood flow to the ...
... an equal opportunity destroyer. It attacks the central nervous ... high-profile victims are celebrated cellist Jacqueline du Pre, whose career ... greatest writers but they are far from alone. ... currently about 400,000 cases in the U.S. and more that ...
... Study finds link between excess weight and the pain disorder, ... News) -- Women who are overweight or obese appear to ... known as fibromyalgia, a new study suggests. , If they ... researcher Paul Mork of Norwegian University of Science and Technology ...
... ... with Invisalign clear aligners, a new technology that may eventually make unattractive, uncomfortable braces ... ever before. , ... Torrance, California (PRWEB) April 29, 2010 -- Torrance orthodontist Dr. Robert Mondavi ...
Cached Medicine News:Health News:Prize4Life Featured in Major Innovation/Prize National Conference 2Health News:Prize4Life Featured in Major Innovation/Prize National Conference 3Health News:IT Leaderboard Showcases Growing Divide Between Talk and Action on Developing Climate Solutions 2Health News:IT Leaderboard Showcases Growing Divide Between Talk and Action on Developing Climate Solutions 3Health News:IT Leaderboard Showcases Growing Divide Between Talk and Action on Developing Climate Solutions 4Health News:Low Testosterone Raises Heart Death Rates in Impotent Men 2Health News:Catching multiple sclerosis before it strikes 2Health News:Catching multiple sclerosis before it strikes 3Health News:Exercise, Weight Control May Keep Fibromyalgia at Bay 2Health News:Invisalign Clear Aligners Available at Blue Sky Family Dental by Torrance Dentist, Dr. Robert Mondavi 2Health News:Invisalign Clear Aligners Available at Blue Sky Family Dental by Torrance Dentist, Dr. Robert Mondavi 3
(Date:8/28/2014)... Minn. , Aug. 28, 2014 MGC Diagnostics ... scheduled a conference call to discuss its financial results ... 31, 2014. The call will be at 4:30 p.m. ... report financial results for the third quarter of fiscal ... 2014. Participants can dial (877) 317-6789 ...
(Date:8/28/2014)... AM MAIN, Germany , August 28, 2014 ... Merz Pharmaceuticals is available free of charge for people from ... dementia within the next two decades. Using a traffic light ... measures with patients at risk. The new "CAIDE ... DEmentia) has been developed in collaboration with Karolinska Institutet in ...
(Date:8/27/2014)... SHENZHEN, China, Aug. 28, 2014 China ... ("Nepstar" or the "Company"), a leading retail drugstore ... directly operated stores, today announced its unaudited financial ... Financial HighlightsFor the quarter ended June 30, ... RMB686.6 million (US$110.7 million) compared to RMB638.8 million in ...
Breaking Medicine Technology:MGC Diagnostics Corporation to Report Third Quarter Fiscal 2014 Financial Results on Tuesday, September 9, 2014 2CAIDE Looks into the Future: New App from Merz Pharmaceuticals Assesses the Risk of Getting Dementia Within the Next 20 Years 2China Nepstar Chain Drugstore Ltd. Reports Second Quarter 2014 Financial Results 2China Nepstar Chain Drugstore Ltd. Reports Second Quarter 2014 Financial Results 3China Nepstar Chain Drugstore Ltd. Reports Second Quarter 2014 Financial Results 4China Nepstar Chain Drugstore Ltd. Reports Second Quarter 2014 Financial Results 5China Nepstar Chain Drugstore Ltd. Reports Second Quarter 2014 Financial Results 6China Nepstar Chain Drugstore Ltd. Reports Second Quarter 2014 Financial Results 7China Nepstar Chain Drugstore Ltd. Reports Second Quarter 2014 Financial Results 8China Nepstar Chain Drugstore Ltd. Reports Second Quarter 2014 Financial Results 9China Nepstar Chain Drugstore Ltd. Reports Second Quarter 2014 Financial Results 10China Nepstar Chain Drugstore Ltd. Reports Second Quarter 2014 Financial Results 11
... reference laboratory and a worldwide leader in ... an extensive test menu of highly complex ... anatomic pathology. Owned by the University of ... half of the nation's university teaching hospitals ...
... reference laboratory and a worldwide leader in ... an extensive test menu of highly complex ... anatomic pathology. Owned by the University of ... half of the nation's university teaching hospitals ...
... reference laboratory and a worldwide leader in ... an extensive test menu of highly complex ... anatomic pathology. Owned by the University of ... half of the nation's university teaching hospitals ...
... ARUP Laboratories is a national reference ... laboratory research and development. ARUP offers an ... unique medical tests in clinical and anatomic ... ARUP Laboratories' clients include more than half ...
Medicine Products: