Navigation Links
Study finds unique HIV vaccine formula elicits strong immune responses
Date:5/22/2008

WORCESTER, Mass.Today, Advanced BioScience Laboratories, Inc. (ABL) and the University of Massachusetts Medical School (UMMS) report that their unique HIV vaccine formulation was effective in eliciting strong and balanced immune responses in healthy human volunteers. The findings are published in the journal Vaccine (Cross-subtype antibody and cellular immune responses induced by a polyvalent DNA primeprotein boost HIV-1 vaccine in healthy human volunteers, Vaccine online, May 22, 2008) In light of these initial findings, additional assays on volunteers samples were done by researchers at the University of Alabama at Birmingham, independently confirming the presence of long lasting and high quality T cell responses against HIV antigens. Results from this confirmatory study are currently available online in the Journal of Virology (April 30, 2008).

In this phase I clinical trial, sponsored by the National Institute of Allergy and Infectious Diseases (NIAID), volunteers first received three injections of a DNA vaccine which expresses protective antigens from the HIV virus, followed by two injections of a protein vaccine whose components matched those included in the DNA vaccine. The report in Vaccine is the first scientific article in which a DNA prime-protein boost combination vaccination method is tested in humans for HIV vaccine development. Scientists at ABL and UMMS and their collaborators discovered that this combination approach is highly effective in inducing strong antibody and cell-mediated immune responses in human volunteers.

Given the challenges of developing a vaccine against HIV, scientists have long believed that a final, effective HIV vaccine will require the induction of balanced responses from both arms of human immune system. Our results demonstrate that it is feasible to use this combination approach to achieve this objective, said Phillip Markham, PhD, of ABL, the Principal Investigator (PI) on this vaccine developmen
'/>"/>

Contact: Office of Public Affairs
public.affairs@umassmed.edu
508-856-2000
University of Massachusetts Medical School
Source:Eurekalert

Page: 1 2 3

Related medicine news :

1. First of its kind study compares high school knee injuries by sport and gender
2. UNC study firms up promise of potential new cervical cancer screening tool
3. Three-Year COPD Study Found No Increase in Cardiac Events With Advair(R) 500/50
4. Study presented at DDW 2008 Confirms that New Device Significantly Improves Detection of Polyps in the Colon
5. Israeli study finds obstructive sleep apnea is health factor from day 1
6. Study finds that recalled Aqua Dots did contain poisonous chemical
7. Study reveals link among childhood allergies, asthma symptoms, and early life exposure to cats
8. Study analyzed SYMBICORT in children with persistent asthma
9. New patient satisfaction study with budesonide/formoterol combination therapy
10. Study: Doctors not always sure when to treat BP in people with diabetes
11. Study concludes no racial disparities in long-term outcomes in recipients of liver transplants
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:7/24/2014)... The Traffic and Leads Training ... to help users generate traffic and leads has just ... excitement throughout the internet marketing community. The excitement surrounding ... Tiffany Hendricks prompting a comprehensive review of the course. ... internet marketing will tell you, it can be quite ...
(Date:7/24/2014)... Ticket Down is a reliable source ... at the Sports Authority Field on July 26th. For the ... has brought some of the best club teams from around the ... still being raved about weeks after its completion, fans – new ... of the biggest stars in the world compete. Some of these ...
(Date:7/24/2014)... The report, “Content Delivery Networks (CDN) ... various sub-segments with an in-depth analysis and forecasting ... restraints for this market with insights on trends, ... tables and 36 figures spread through 157 pages ... Market” at http://www.marketsandmarkets.com/Market-Reports/content-delivery-networks-cdn-market-657.html . , Early ...
(Date:7/24/2014)... New York, New York (PRWEB) July 24, 2014 ... of GranuFlo lawsuits ( http://www.injurybeacon.com/granuflo-dialysis/lawsuit/ ) in ... issued a qualified protective order for plaintiff medical ... and Accountability Act. According to the July 16th ... granted attorneys for Fresenius Medical Care ...
(Date:7/24/2014)... (PRWEB) July 24, 2014 In a July ... expert and founder of Lotus Blossom Consulting LLC , ... entitled Three Ways to Cut the High Cost of ... to minimize costs is to maximize your chance of success ... on choosing a clinic. , “I am always happy ...
Breaking Medicine News(10 mins):Health News:Traffic And Leads Training Academy - Review Examining Jeff Johnson’s New IM Course Released 2Health News:Manchester United vs. AS Roma Tickets Denver Sports Authority Field at Mile High: Ticket Down Cuts Ticket Prices for Guinness International Champions Cup Match 2Health News:Manchester United vs. AS Roma Tickets Denver Sports Authority Field at Mile High: Ticket Down Cuts Ticket Prices for Guinness International Champions Cup Match 3Health News:CDN Market by Delivery Technologies & Solutions Expected to Reach $12.16 Billion by 2019 - New Report by MarketsandMarkets 2Health News:CDN Market by Delivery Technologies & Solutions Expected to Reach $12.16 Billion by 2019 - New Report by MarketsandMarkets 3Health News:CDN Market by Delivery Technologies & Solutions Expected to Reach $12.16 Billion by 2019 - New Report by MarketsandMarkets 4Health News:GranuFlo Lawsuits Move Forward in Federal Court, With Issuance of Protective Order for HIPAA Information, Bernstein Liebhard LLP Reports 2Health News:GranuFlo Lawsuits Move Forward in Federal Court, With Issuance of Protective Order for HIPAA Information, Bernstein Liebhard LLP Reports 3Health News:GranuFlo Lawsuits Move Forward in Federal Court, With Issuance of Protective Order for HIPAA Information, Bernstein Liebhard LLP Reports 4Health News:Mindy Berkson, Infertility Expert and Founder, Lotus Blossom Consulting LLC: Leading the Pathway to Parenthood 2Health News:Mindy Berkson, Infertility Expert and Founder, Lotus Blossom Consulting LLC: Leading the Pathway to Parenthood 3
... Elsevier, a world-leading publisher of medical information products and ... Medical Press (PUMP) it has donated over 5,000 books ... The initiative is supported by the Development Centre for ... book donation is in line with the spirit of ...
... Rainbow Kitchen celebrates its 25th year of service to the ... period of economic hardship means that the help the organization ... , The 25th anniversary will be marked with a ... Scott Lammie - UPMC Health Plan,s Chief Financial Officer and ...
... ... Electronic Payment Exchange (EPX), a leading merchant acquirer ... data field encryption best practices provides welcome leadership to merchants, technology ... of data breach. EPX is the first payment processor to offer ...
... ... direct-to-consumer provider of premium dietary supplements, announces the release of their Mediterranean Diet ... ... a leading direct-to-consumer provider of premium dietary supplements, announces the release of their ...
... ... therapy affect integration into society,• Marriage is predicted by height, physical functioning, cognitive outcomes ... Philadelphia ... effects of cancer treatment on physical health, and results of a new study suggest ...
... LAKE CITY, Oct. 7 Utah residents will have access ... tomorrow. The Utah Drug Card is a free discount prescription ... to 75% on prescription drugs at retail pharmacies. All Utah ... printing a card on the program,s website www.utahdrugcard.com ...
Cached Medicine News:Health News:Elsevier's Health Sciences Division and Peking University Medical Press cooperate on book donation 2Health News:Rainbow Kitchen Celebrates 25th Anniversary in Pittsburgh 2Health News:Electronic Payment Exchange Welcomes New Visa Best Practices for Data Field Encryption 2Health News:Electronic Payment Exchange Welcomes New Visa Best Practices for Data Field Encryption 3Health News:Purity Products Releases Their Brand New Mediterranean Diet Resveratrol Formula 2Health News:Survivors of Childhood Cancer Less Likely to Marry 2Health News:Survivors of Childhood Cancer Less Likely to Marry 3Health News:Survivors of Childhood Cancer Less Likely to Marry 4
(Date:7/24/2014)... VIEW, Calif. , July 24, 2014 /PRNewswire/ ... a leading provider of medication and supply management ... a conference call Thursday, July 31, to discuss ... , Omnicell Second Quarter 2014 earnings conference ... 1:30 p.m. PTWho:  , Randall Lipps, chairman, president ...
(Date:7/24/2014)... 24, 2014  IGI Laboratories, Inc. (NYSE MKT: IG), a ... announced its financial results for the second quarter ended June ... , Total revenues of $6.5 million in the second quarter ... in 2013 , Total revenues of $13.3 million for ... 78% over the same period in 2013 , Total ...
(Date:7/24/2014)... -- Many new dentists who are opening their own offices ... practice will be a success. DentalDisposables.net is here to say ... most can make all the difference. Dentistry is a business ... purchasing discount dental supplies can make the difference ... dentists across the United States and ...
Breaking Medicine Technology:Omnicell to Release Second Quarter 2014 Earnings Results on July 31 2IGI Laboratories Announces Second Quarter 2014 Results 2IGI Laboratories Announces Second Quarter 2014 Results 3IGI Laboratories Announces Second Quarter 2014 Results 4IGI Laboratories Announces Second Quarter 2014 Results 5IGI Laboratories Announces Second Quarter 2014 Results 6IGI Laboratories Announces Second Quarter 2014 Results 7Dental Supplies Online is Key to Dental Success...Really! 2
... 6, 2011 In a article published in the August ... Bryan A. Liang, Shapiro Distinguished Professor of Health Law & ... School of Law (CWSL); and Mr. Tim Mackey, Senior Research ... Program at University of California, San Diego – San Diego ...
... The " Global Fetal (Labor & Delivery) ... fetal and neonatal care equipment market by types and studies the ... and neonatal care market across 18 countries in North America, Europe, ... Explore market data tables and in-depth TOC on   ...
Cached Medicine Technology:JMIR Article by IHLS Authors Discusses Global Public Health Implications of Social Media Direct-to-Consumer Advertising by Illicit Online Pharmacies and Private Entities 2MarketsandMarkets: Global Fetal and Neonatal Care Equipment Market Forecast (2011-2016) 2MarketsandMarkets: Global Fetal and Neonatal Care Equipment Market Forecast (2011-2016) 3MarketsandMarkets: Global Fetal and Neonatal Care Equipment Market Forecast (2011-2016) 4
... ARUP Laboratories is a national reference laboratory ... research and development. ARUP offers an extensive ... medical tests in clinical and anatomic pathology. ... Laboratories' clients include more than half of ...
... reference laboratory and a worldwide leader in ... an extensive test menu of highly complex ... anatomic pathology. Owned by the University of ... half of the nation's university teaching hospitals ...
... ARUP Laboratories is a national reference laboratory ... research and development. ARUP offers an extensive ... medical tests in clinical and anatomic pathology. ... Laboratories' clients include more than half of ...
... national reference laboratory and a worldwide leader ... offers an extensive test menu of highly ... and anatomic pathology. Owned by the University ... than half of the nation's university teaching ...
Medicine Products: