Navigation Links
Study finds tiny, targeted drug particles may be effective in treating chronic diseases
Date:3/20/2013

Doses of medicine 100,000 times smaller than the diameter of a human hair prevent the tissue damage associated with atherosclerosis and other chronic diseases in mice. As part of a National Institutes of Health-sponsored project led by Zahi Fayad, PhD, of the Icahn School of Medicine at Mount Sinai, researchers found that these nanomedicines are able to home specifically to damaged tissue to repair it. This study was published online this week in Proceedings of the National Academy of Sciences.

Inflammation is the body's natural defense mechanism against invading organisms and tissue injury. When under attack by a pathogen such as a virus, the body mounts an immune response that causes inflammation to clear the attacker so the body can return to a healthy state. Scientists believe that in chronic diseases like heart disease or diabetes, the body mounts a prolonged immune response resulting in chronic inflammation and tissue damage. Since the level of inflammation in these diseases is very high, targeted therapeutic solutions are required to help keep inflammation contained.

"Numerous studies have shown that inflammation is the foundation for many chronic diseases, and we need therapies that help resolve the tissue damage that results from that inflammation," said Dr. Fayad, who is the Director of the Translational and Molecular Imaging Institute and Professor of Radiology and Medicine at The Mount Sinai Medical Center. "Nanomedicine is the next frontier in successfully treating and preventing the progression of these conditions without the side effects that come from standard drug therapy."

Researchers at Brigham and Women's Hospital (BWH), Columbia University Medical Center, Massachusetts Institute of Technology, and Mount Sinai developed a nanoparticle that mimics a protein that is critical to the resolution of inflammation in the body. The research team incorporated the nanoparticle into a molecule consisting of three parts
'/>"/>

Contact: Mount Sinai Press Office
newsmedia@mssm.edu
212-241-9200
The Mount Sinai Hospital / Mount Sinai School of Medicine
Source:Eurekalert

Page: 1 2

Related medicine news :

1. Anxiety, Depression May Triple Risk of Death for Heart Patients: Study
2. Plans to Penalize Non-Emergency Use of ERs Flawed: Study
3. Study could aid development of new drugs to treat gout
4. A Third of U.S. Seniors Die With Dementia, Study Finds
5. Gene Mutations Appear Key to Childhood Leukemia Risk, Study Says
6. First of its kind study in Canada looks at who is taking aspirin to prevent heart attack or stroke
7. Switch to Skim Milk Wont Prevent Toddlers Obesity: Study
8. Fewer Kids Getting Hurt in Most Sports, Study Finds
9. Black Children Less Likely to Get Antibiotics: Study
10. BioPharm Systems Unveils Study Data Mapper to Simplify the Preparation and Reporting of Clinical Data
11. Discounts on purchases of healthy foods can improve diets, study finds
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:9/17/2014)... Oxford, UK, September 17, 2014 The International Journal ... has opened up its archive of previously published content: after ... read. A key aim of the IJS is ... hoped that by making these articles available to all will ... Editor-in-Chief of IJS said, "The journal has always ...
(Date:9/17/2014)... WA (PRWEB) September 17, 2014 A ... in fiscal year 2010 revealed 3.2% of these patients developed ... and 2.4% labeled as superficial SSIs. The average difference for ... 876, after adjustments. , The study, conducted by Marin Schweizer, ... the University of Iowa, found the treatment costs for the ...
(Date:9/17/2014)... September 17, 2014 The probability of ... with regular screening and examination, a healthy diet could ... of Epicure with the Chef MDs, renowned ... Paul Rusilko to prepare a delicious Fish Moilee. , ... diets that influence risk of prostate cancer, uncommonly found ...
(Date:9/17/2014)... Acceleratio Ltd., an innovative software development ... of Server Monitoring Toolkit , a web ... It brings real-time server monitoring via a live ... enhanced features that significantly improve troubleshooting and detection ... agentless data collection, a user-friendly interface, and many ...
(Date:9/17/2014)... September 17, 2014 Kamut International is ... a key ingredient in Michael Angelo’s new “Made With ... new fully organic lasagna ready made, frozen meal. Michael ... pastas and these new products align well with Kamut ... all KAMUT® Brand wheat must be grown certified organic. ...
Breaking Medicine News(10 mins):Health News:Three Ways to Minimize Costs Associated with Surgical Site Infections 2Health News:Boost Prostate Health with Epicure with the Chef MDs 2Health News:New Server Monitoring Toolkit v6 Brings Real-Time Windows Server Monitoring and New Server Reports 2Health News:New Server Monitoring Toolkit v6 Brings Real-Time Windows Server Monitoring and New Server Reports 3Health News:KAMUT® Brand Wheat Delivers a High Quality Ingredient and Authentic Italian Taste for Michael Angelo’s New Ready-Made Meals featuring Organic Ingredients 2
... A large-scale data review by researchers in China of ... the endoscopic procedure to be safe and effective for ... a pooled detection rate of 68.1 percent for all ... be the most common indication, with a relatively high ...
... cancer patients who use a new combination of the ... Gy) before surgery have an 88 percent chance of ... randomized trial presented at the plenary session, October 3, ... Society for Radiation Oncology (ASTRO). "The results of ...
... 2011) Researchers in Japan have completed a study showing ... pulp can be grafted and produce bone regeneration between parents ... of Cell Transplantation (20:7), now freely ... a number of reasons, and autogenous bone grafting - using ...
... , MONDAY, Sept. 26 (HealthDay News) -- ... inhibitor (SSRI) antidepressants and antiplatelet drugs such as aspirin ... those who take anti-clotting drugs only, a new study ... and Lexapro. Antiplatelet drugs prevent blood cells from ...
... the Witwatersrand goldfields, not far from bustling Johannesburg, South Africa, ... littered with mounds of waste and underlain by a deep ... with water. Today, the mines are producing less and less ... estimate the volume of acid mine drainage from abandoned mines ...
... Eating fruits and vegetables may reduce the risk of some ... examined the diets of 918 colorectal cancer patients and 1,021 ... consumption of certain vegetables and fruits were associated with a ... -- that is, the upper and lower portions of the ...
Cached Medicine News:Health News:Study examining large-scale data of double balloon enteroscopy shows it is safe and effective 2Health News:Study examining large-scale data of double balloon enteroscopy shows it is safe and effective 3Health News:Study examining large-scale data of double balloon enteroscopy shows it is safe and effective 4Health News:Chemo plus radiation before surgery increases tumor response for rectal cancer 2Health News:Cell Transplantation study shows bone growth from implanted tooth and dental pulp stem cells 2Health News:Certain Antidepressants With Blood Thinners May Pose Risk for Heart Patients 2Health News:Broccoli, Cabbage, Other Veggies May Protect Against Colon Cancer 2
(Date:9/17/2014)... Pa. , Sept. 17, 2014  Fortune Oil ... officially changed its name to Manzo Pharmaceuticals, Inc. with ... to take effect today, September 17, 2014. Also taking ... The approval is a pivotal event in ... . Mr. Manzo explained, "We could not proceed with ...
(Date:9/17/2014)...  Auxilium Pharmaceuticals, Inc. (NASDAQ: AUXL ), ... received an unsolicited, non-binding proposal from Endo International plc ... the outstanding shares of Auxilium common stock at a ... stock, subject to due diligence, financing and other conditions. ... received from Endo on Friday evening is reproduced below. ...
(Date:9/17/2014)... 2014 Mindray (NYSE: MR)announced its new generation ... system has been showcased for the first time at ... September, and is scheduled for availability in the U.S. ... the most efficient workhorse in the mid-range segment, the ... perfectly optimized user experience including a gesture-sensitive touch screen, ...
Breaking Medicine Technology:Fortune Oil and Gas, Inc. announces 1 for 10 reverse split along with a name change to Manzo Pharmaceuticals is now effective 2Fortune Oil and Gas, Inc. announces 1 for 10 reverse split along with a name change to Manzo Pharmaceuticals is now effective 3Auxilium Responds To Unsolicited Proposal From Endo International 2Auxilium Responds To Unsolicited Proposal From Endo International 3Auxilium Responds To Unsolicited Proposal From Endo International 4Auxilium Responds To Unsolicited Proposal From Endo International 5Auxilium Responds To Unsolicited Proposal From Endo International 6Auxilium Responds To Unsolicited Proposal From Endo International 7Quality Exams at Your Fingertips 2
The Flash MiniLabeler products can be configured to label microplates, tubes, vials, glass slides, circuit boards and a wide array of small products. Systems perform wrap around (tube or package) lab...
Shandon Laser MicroWriter is a laser labeling system developed specifically for anatomical pathology....
Modular Slide Storage Cabinet has a durable cold rolled steel construction with baked on epoxy finish. Drawers slide smoothly and quietly....
Store microscope slides with ease, speed, efficiency....
Medicine Products: