Navigation Links
Study finds that blood test can gauge prostate cancer risk
Date:1/16/2008

WINSTON-SALEM, N.C. New genomics research has found that a simple blood test can determine which men are likely to develop prostate cancer. Researchers at Wake Forest University School of Medicine and colleagues found that five genetic variants previously associated with prostate cancer risk have a strong cumulative effect.

Reporting in New England Journal of Medicine, researchers found that a man with four of the five variants has an increased risk of 400 to 500 percent compared to men with none of the variants. The researchers then added a family history of prostate cancer to the equation for a total of six risk factors. A man with at least five of the six factors had increased risk of more than 900 percent.

The article was published Online First today and will be included in the Feb. 28 print issue.

The scientists say each variant was independently associated with prostate cancer risk and that the variants are fairly common in the population. Together, these five variants and a family history accounted for almost half (46 percent) of prostate cancer patients. The study involved analyzing DNA samples from 2,893 men with prostate cancer and 1,781 healthy individuals of similar ages all participants of a prostate cancer study in Sweden.

This is significant and could affect clinical care, said senior researcher Jianfeng Xu, M.D., Dr. PH., professor of epidemiology and cancer biology. The information could substantially improve physicians ability to assess risk and determine the need for more aggressive screening or even a biopsy.

For example, the test may be especially useful in men with a family history of prostate cancer or those who have a marginally elevated PSA (prostate specific antigen), he said.

The study is also important because it is one of the first to illustrate how a combination of several genes can affect risk of disease. Genomics teams nationwide are currently searching for combinations o
'/>"/>

Contact: Karen Richardson
krchrdsn@wfubmc.edu
336-716-4453
Wake Forest University Baptist Medical Center
Source:Eurekalert

Page: 1 2 3

Related medicine news :

1. Penn study finds pro-death proteins required to regulate healthy immune function
2. New study shows promise in reducing surgical risks associated with surgical bleeding
3. Study, meta-analysis examine factors associated with death from heatstroke
4. Study suggests loss of 2 types of neurons -- not just 1 -- triggers Parkinsons symptoms
5. Study says COPD testing is not measuring up
6. Preclinical study suggests organ-transplant drug may aid in lupus fight
7. Ability to cope with stress can increase good cholesterol in older white men, study finds
8. High alcohol consumption increases stroke risk, Tulane study says
9. Mailman School of Public Health study examines link between racial discrimination and substance use
10. Pitt study finds inequality in tobacco advertising
11. Stanford study highlights cost-effective method of lowering heart disease risks
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:8/21/2014)... PA (PRWEB) August 21, 2014 The ... Crossing Historic Park in Washington Crossing, Pennsylvania on Thursday, ... the park. “We have been looking for different ways ... said Matt Kiernan, Partner with Pharmica Consulting. “When we ... part of U.S. history, we jumped at the opportunity.” ...
(Date:8/21/2014)... She was 12 years old when the unthinkable happened – ... correct her frequent headaches failed. , In her new ... her journey of overcoming devastating obstacles involving dual disability, greed ... justice for years. , “My faith in God helped ... light,” Strom-Stewart said. “But it took me more than a ...
(Date:8/21/2014)... 21, 2014 The rising numbers of teen ... Beach, FL. For many years, countless lives have been lost ... the community a new helpline was established to provide a ... who are seeking to overcome their youth substance abuse ... Beach helpline at (561) 257-4053, parents and their teens can ...
(Date:8/21/2014)... Michael E. Steuer , local doctor in Memphis, TN, ... City with recent philanthropy at local synagogue. “The state of ... says friend and Rabbi David Julian of Or Chadash in ... in-house for the needy and teaching Hebrew to students, Steuer ... synagogue. And to remain close with the development of Israel, ...
(Date:8/21/2014)... SC (PRWEB) August 21, 2014 ... of seven start-ups selected to participate in the ... provides entrepreneur mentorship, curriculum sessions and valuable resources.he ... businesses in the region. Each start-up selected for ... support in order to help businesses grow quickly, ...
Breaking Medicine News(10 mins):Health News:Pharmica Spends the Day Helping to Preserve Washington Crossing Historic Park 2Health News:The Dramatic, Uplifting Story from a Brain Injured Woman 2Health News:Troubled Teens in Boynton Beach, FL Turn to Helpline for Valuable Assistance 2
... possessing gun in assault situation 4.5 times more likely to be ... In a first-of-its-kind study, epidemiologists at the University of ... not protect those who possessed them from being shot in an ... 4.5 times more likely to be shot in an assault than ...
... ... today that Wayne Cockburn, President and CEO will present an overview of Muscle ... pain, neurology, medical device , ... Huntington Beach, CA (PRWEB) September 30, 2009 -- iTech Medical, Inc. (OTCBB: ...
... ... Publishing releases CNS Complications in the Immunocompromised Patient, an ABR-approved online radiology self-assessment ... ... 2009 -- Oakstone Medical Publishing announces the launch of the ABR-approved radiology online ...
... , WASHINGTON, Sept. 29 The American Federation of Government Employees ... Management that premiums under FEHBP would be rising by an average ... average is the fact that for 60% of the enrollees in ... premiums will be going up by 15% for self coverage and ...
... Cadence Pharmaceuticals, Inc. (Nasdaq: CADX ), a biopharmaceutical ... candidates principally for use in the hospital setting, announced ... will present the company,s corporate overview on Tuesday, October ... during the JMP Securities Healthcare Focus Conference at the ...
... and post-menopausal women who self-rated themselves as being sexually ... scores for "positive well-being" and "vitality," compared with sexually ... active more than twice a month. The study, ... , also uncovered a positive association between age and ...
Cached Medicine News:Health News:Penn Study Asks, Protection or Peril? Gun Possession of Questionable Value in an Assault 2Health News:Penn Study Asks, Protection or Peril? Gun Possession of Questionable Value in an Assault 3Health News:iTech Medical to Present at BioContact Qubec 2009 2Health News:iTech Medical to Present at BioContact Qubec 2009 3Health News:iTech Medical to Present at BioContact Qubec 2009 4Health News:iTech Medical to Present at BioContact Qubec 2009 5Health News:Oakstone Medical Publishing Introduces an Online ABR Qualified Self-Assessment Module for Radiologists Designed to Satisfy MOC Requirements 2Health News:Sexually satisfied women have better general well-being and more vitality 2Health News:Sexually satisfied women have better general well-being and more vitality 3
(Date:8/20/2014)... PLAINFIELD, N.J. , Aug. 20, 2014 PTC Therapeutics, ... will participate at two upcoming investor conferences: - ... Seasons Hotel in Boston on Wednesday, ... Biotech Conference at The Mandarin Oriental Boston on Thursday, September ... present a company update at the Bank of America Merrill ...
(Date:8/20/2014)... YORK , Aug. 20, 2014 ... is available in its catalogue: The ... IVD Industry http://www.reportlinker.com/p01618927/The-Impact-of-Healthcare-Reform-PPACA-On-the-US-IVD-Industry.html ... Act" (H.R. 3590) is complex legislation that affects ... of its provisions are beginning to take effect ...
(Date:8/20/2014)... 20, 2014 Reportlinker.com announces that ... in its catalogue: Personal Accident ... and Opportunities to 2017 ... The report provides in depth market analysis, ... accident and health insurance segment, including: • ...
Breaking Medicine Technology:PTC Therapeutics to Participate at Upcoming Investor Conferences 2The Impact of Healthcare Reform (PPACA) On the U.S. IVD Industry 2The Impact of Healthcare Reform (PPACA) On the U.S. IVD Industry 3The Impact of Healthcare Reform (PPACA) On the U.S. IVD Industry 4The Impact of Healthcare Reform (PPACA) On the U.S. IVD Industry 5The Impact of Healthcare Reform (PPACA) On the U.S. IVD Industry 6Personal Accident and Health Insurance in Canada, Key Trends and Opportunities to 2017 2Personal Accident and Health Insurance in Canada, Key Trends and Opportunities to 2017 3Personal Accident and Health Insurance in Canada, Key Trends and Opportunities to 2017 4Personal Accident and Health Insurance in Canada, Key Trends and Opportunities to 2017 5Personal Accident and Health Insurance in Canada, Key Trends and Opportunities to 2017 6Personal Accident and Health Insurance in Canada, Key Trends and Opportunities to 2017 7Personal Accident and Health Insurance in Canada, Key Trends and Opportunities to 2017 8Personal Accident and Health Insurance in Canada, Key Trends and Opportunities to 2017 9Personal Accident and Health Insurance in Canada, Key Trends and Opportunities to 2017 10Personal Accident and Health Insurance in Canada, Key Trends and Opportunities to 2017 11Personal Accident and Health Insurance in Canada, Key Trends and Opportunities to 2017 12Personal Accident and Health Insurance in Canada, Key Trends and Opportunities to 2017 13Personal Accident and Health Insurance in Canada, Key Trends and Opportunities to 2017 14Personal Accident and Health Insurance in Canada, Key Trends and Opportunities to 2017 15Personal Accident and Health Insurance in Canada, Key Trends and Opportunities to 2017 16Personal Accident and Health Insurance in Canada, Key Trends and Opportunities to 2017 17Personal Accident and Health Insurance in Canada, Key Trends and Opportunities to 2017 18Personal Accident and Health Insurance in Canada, Key Trends and Opportunities to 2017 19Personal Accident and Health Insurance in Canada, Key Trends and Opportunities to 2017 20Personal Accident and Health Insurance in Canada, Key Trends and Opportunities to 2017 21Personal Accident and Health Insurance in Canada, Key Trends and Opportunities to 2017 22Personal Accident and Health Insurance in Canada, Key Trends and Opportunities to 2017 23
... REDWOOD CITY, Calif., March 19, 2012 Ingenuity Systems, ... life science researchers, today announced that the Weill Cornell ... iReport for use in its sequencing core facility.  Variant ... the output of whole genome and exome sequencing experiments ...
... 19, 2012  Johnson & Johnson (NYSE: JNJ) will provide ... parties on Monday, March 26th at approximately 10:30 ... College of Cardiology (ACC) Annual Scientific Sessions in ... of the EINSTEIN-PE study in treating patients with ...
Cached Medicine Technology:Weill Cornell Medical College Selects Ingenuity® Variant Analysis™ and Ingenuity® iReport™ for Sequencing Core Facility 2
Superior imaging through a 410,000 pixel CCD, unseen color replication from a digital signal processor in the scope, and the added benefit of four way tip deflection make the TF410 a superior choice ...
The ACMI™ Operative Laparoscopy System is designed for single- and dual-incision CO2 laser procedures and is used with 45cm laparoscopic instruments....
Stryker autoclavable pediatric laparoscopes provide equivalent brightness and resolution along with the unparalleled durability found in larger laparoscopes....
The Olympus full range of laparoscopes includes a range of diameters and directions of view -12 mm HDTV compatible model as well as a choice of 10 mm, 5 mm full screen and 3 mm....
Medicine Products: