Navigation Links
Study finds testosterone therapy may reduce risk of cardiovascular disease
Date:10/23/2013

(Boston)Research from Boston University School of Medicine (BUSM) suggests that testosterone treatment in hypogonadal (testosterone deficient) men restores normal lipid profiles and may reduce the risk of cardiovascular disease. These finding currently appear online in the International Journal of Clinical Practice.

Metabolic syndrome (MetS) is associated with increased risk for cardiovascular disease and diabetes mellitus. There is a strong association between MetS and testosterone deficiency.

Hypogonadal men are more likely to suffer from metabolic syndrome characterized by dyslipidemia, insulin resistance, diabetes and hypertension. Additionally, obese and overweight men also may exhibit testosterone deficiency.

In this observational study, BUSM researchers investigated the effects of testosterone treatment in 255 hypogonadal men between the ages of 33-69 and followed them for a period of five years. They found that men treated with testosterone therapy experienced a gradual reduction of their total cholesterol, low density lipoprotein cholesterol (LDL/bad cholesterol), triglycerides and increased high density lipoprotein (HDL/(good cholesterol). "In addition to improving their cholesterol levels, we found that the testosterone treatment resulted in marked reductions in systolic and diastolic blood pressure as well, suggesting amelioration of hypertension," explained lead author Abdulmaged M. Traish, MBA, PhD, professor of biochemistry and urology as well as Research Director of the Institute of Sexual Medicine at BUSM.

Traish found this treatment also reduced fasting blood glucose and hemoglobin A1c, a surrogate marker of hyperglycemia, suggesting that testosterone treatment may improve insulin sensitivity and hyperglycemic control. It also reduced the levels of inflammatory biomarkers such as C-reactive protein (CRP) and markers of liver dysfunction such as alanine aminotransferase and aspartate aminotransferase, suggesting reduction in the inflammation responses.

"These data are congruent with our previous work in which we reported that long-term testosterone resulted in a gradual decline in weight and waist circumference and strongly suggests that testosterone therapy in hypogonadal men may prove useful in reducing the risk of cardiometabolic diseases," he added.


'/>"/>

Contact: Gina DiGravio
gina.digravio@bmc.org
617-638-8480
Boston University Medical Center
Source:Eurekalert

Related medicine news :

1. New Study Tracks Latest Changes in New York Workers’ Compensation System after 2007 Reforms
2. Los Angeles Parathyroid Surgeon Responds to Study Indicating Advantages of Minimally Invasive Parathyroid Surgery
3. Flu shot halves risk of heart attack or stroke in people with history of heart attack, study finds
4. Flu shot halves risk of heart attack or stroke in people with history of heart attack, study finds
5. Opioids for chronic pain: Study looks at how patients and their doctors talk about risks
6. Study Examines Connections Between Depression and Breast Cancer, Allsup Reports
7. New Autism Study Reveals Effectiveness of Web-Based Intervention Tool for Challenging Behaviors
8. Tufts Medical Center to lead 20-center study on vitamin Ds effect on Type 2 diabetes
9. UCLA gets $7 million to study substance use and HIV among minority men who have sex with men
10. Large prospective study finds long-term obesity is associated with poorer pancreatic cancer survival
11. Study examines endoscopic ultrasound-guided drainage of pancreatic pseudocysts
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:2/12/2016)... ... ... According to an article published February 4th on mySA, robotically ... hernia repairs throughout the United States. Commenting on this article, Beverly Hills hernia repair ... has not only been expected, but it seems to be a natural result of ...
(Date:2/12/2016)... ... February 12, 2016 , ... CDRH Enforcement Trends: , Back to the Future , Feb. ... , As Winston Churchill said, “Those who don’t learn from history are doomed to repeat ... when they come knocking this year. But that takes time. , Take a close ...
(Date:2/12/2016)... , ... February 12, 2016 , ... ... announced that nominations have closed for the ISE Southeast Awards 2016. Finalists and ... announced at the ISE® Southeast Executive Forum and Awards Gala on March 15, ...
(Date:2/12/2016)... (PRWEB) , ... February 12, 2016 , ... AssureVest Insurance ... areas, is initiating a charity drive that will raise funds earmarked to purchase computers ... C. Tayloe Elementary School. , “My school is in a low-income area and has ...
(Date:2/12/2016)... ... February 12, 2016 , ... Donor Network West, the organ procurement ... announced a partnership with San Ramon Regional Medical Center. Under the collaboration, the first ... a way to accommodate a more certain time frame for donor families for the ...
Breaking Medicine News(10 mins):
(Date:2/12/2016)... Holdings, Inc. (NASDAQ: IPHS ), a leading international producer ... will host a live conference call on Tuesday, February 23, ... and full year 2015 results. --> ... and full year results will be issued on Monday, February ... --> The conference call can be accessed ...
(Date:2/12/2016)... Inc., a medical device company that pioneered the use of the ... device indicated for fusion for certain disorders of the sacroiliac (SI) ... Contractor (MAC) covering the states of Connecticut , ... Massachusetts , Minnesota , ... Rhode Island , Vermont and ...
(Date:2/12/2016)... Feb. 12, 2016 On Thursday, Feb. 11, ... at St. David,s North Austin Medical Center successfully completed ... Xi ® Surgical System with Trumpf Medical,s ... Thiru Lakshman , M.D., colorectal surgeon at the ... utilizing Integrated Table Motion technology, which seamlessly combines the ...
Breaking Medicine Technology: