Navigation Links
Study finds structural brain alterations in patients with irritable bowel syndrome
Date:7/22/2010

A large academic study has demonstrated structural changes in specific brain regions in female patients with irritable bowel syndrome (IBS), a condition that causes pain and discomfort in the abdomen, along with diarrhea, constipation or both.

A collaborative effort between UCLA and Canada's McGill University, the study appears in the July issue of the journal Gastroenterology.

The findings show that IBS is associated with both decreases and increases in grey matter density in key areas of the brain involved in attention, emotion regulation, pain inhibition and the processing of visceral information.

IBS affects approximately 15 percent of the U.S. population, primarily women. Currently, the condition is considered by the medical field to be a "functional" syndrome of the digestive tract not working properly rather than an "organic" disorder with structural organ changes. Efforts to identify structural or biochemical alterations in the gut have largely been unsuccessful. Even though the pathophysiology is not completely understood, it is generally agreed that IBS represents an alteration in brain-gut interactions.

These study findings, however, show actual structural changes to the brain, which places IBS in the category of other pain disorders, such as lower back pain, temporomandibular joint disorder, migraines and hip pain conditions in which some of the same anatomical brain changes have been observed, as well as other changes. A recent, smaller study suggested structural brain changes in IBS, but a larger definitive study hadn't been completed until now.

"Discovering structural changes in the brain, whether they are primary or secondary to the gastrointestinal symptoms, demonstrates an 'organic' component to IBS and supports the concept of a brain-gut disorder," said study author Dr. Emeran Mayer, professor of medicine, physiology and psychiatry at the David Geffen School of Medicine a
'/>"/>

Contact: Rachel Champeau
rchampeau@mednet.ucla.edu
310-794-2270
University of California - Los Angeles
Source:Eurekalert  

Page: 1 2 3

Related medicine news :

1. Study describes health effects of occupational exposures in Paducah Gaseous Diffusion Plant workers
2. Study links more time spent sitting to higher risk of death
3. NIH-funded study finds early HAART during TB treatment boosts survival rate in co-infected people
4. Study Points to Molecular Origins of Celiac Disease
5. FDA Puts Partial Hold on Avandia Safety Study
6. Not Every ACL Tear Needs Early Surgery, Study Suggests
7. Most men in long-term study of HIV report low use of illicit drugs
8. Gladstone and Lundbeck collaborate to study neurovascular disease
9. New Study Finds HPV Vaccine Protects Against Genital Warts
10. Vaginal Gel Cuts Risk of HIV Infection, Study Shows
11. Research consortium at CHLA receives $410,000 to study leukemia and lymphoma
Post Your Comments:
*Name:
*Comment:
*Email:
Related Image:
Study finds structural brain alterations in patients with irritable bowel syndrome
(Date:10/1/2014)... October 01, 2014 After undergoing a ... chamber of commerce to join, Living Well Assisted Living ... Commerce in Marin County, the home of its headquarters. ... the moment, and the thought of adding one more ... to keep looking for the right chamber to join ...
(Date:10/1/2014)... Angeles, CA (PRWEB) October 01, 2014 ... debut documentary film, "Beautiful Births", emerging filmmaker Jacqui Blue ... help other women discover the truth about natural birth. ... from people all over the world and has been ... birth. Many of the topics highlighted in the film ...
(Date:10/1/2014)... 2014 Indosoft, Inc., a leading provider of ... it has added support for Sangoma Lyra ... Indosoft have a history of bringing innovative products to ... offers a significant benefit to those using Asterisk as a ... available to users of Q-Suite. , In the past decades, ...
(Date:10/1/2014)... QueenBeeTickets.com is giving music fans the opportunity to purchase ... tour, which has him traveling from November 19 until December ... to view the selection of presale tickets available at ... to come out on October 14, and the tour in ... tickets are available for shows that will take place in ...
(Date:9/30/2014)... one third of medical and nursing students in developing ... own countries after graduation, while less than one fifth ... they are needed most, according to a new study. ... driving the current outbreak of Ebola in western Africa. ... three of the world,s poorest countries (Guinea, Sierra Leone ...
Breaking Medicine News(10 mins):Health News:Living Well Joins San Rafael Chamber of Commerce 2Health News:Living Well Joins San Rafael Chamber of Commerce 3Health News:Filmmaker Jacqui Blue's Beautiful Births Documentary, "Really Touched My Heart" 2Health News:Filmmaker Jacqui Blue's Beautiful Births Documentary, "Really Touched My Heart" 3Health News:Filmmaker Jacqui Blue's Beautiful Births Documentary, "Really Touched My Heart" 4Health News:Indosoft Announces Q-Suite Support For Sangoma Lyra 2Health News:Bob Seger Presale Tickets: QueenBeeTickets.com Delights Fans with Discounted Tickets for All 20 Stops on Seger’s “Ride Out” Tour with The Silver Bullet Band 2Health News:Developing countries should enroll medical and nursing students from rural areas 2Health News:Developing countries should enroll medical and nursing students from rural areas 3
... , , EXTON, Pa., ... ViroPharma Incorporated (Nasdaq: VPHM ) today announced that the ... of Generic Drugs (OGD) draft guidelines on bioequivalence (BE) for Vancocin(R) ... life-threatening bacterial infections of the gastrointestinal (GI) tract, Clostridium difficile ...
... ... versus Goliath struggle raging in the West, joins the stellar line-up at the ... and in Los Angeles (August 7 - 13). The film will also air ... Impact series on Planet Green, a network of Discovery Communications.,Split Estate maps a ...
... , , , ... (Nasdaq: CLRT ), a premier anatomic pathology and molecular testing ... results for the second quarter and six months ended June 30, 2009. ... second quarter of 2009 versus the second quarter of 2008, and a ...
... EAST RUTHERFORD, N.J., Aug. 4 Cambrex Corporation (NYSE: CBM ) ... Highlights , , Sales ... Reported sales declined by 9.8% for the quarter. , EBITDA ... year (see attached table). , Debt, net of cash was ...
... and MISSISSAUGA, ON, Aug. 4 /PRNewswire-FirstCall/ - Covidien (NYSE: ... products, and Nuvo Research Inc. (TSX:NRI), a Canadian drug ... Drug Administration (FDA) has set a new action date ... Pennsaid (diclofenac sodium) topical solution 1.5% w/w of November ...
... , WALTHAM, Mass., Aug. 4 Inverness ... leader in enabling individuals to take charge of their health ... management, today announced that it intends to offer $150 million ... of the notes will be guaranteed by certain of Inverness, ...
Cached Medicine News:Health News:ViroPharma Announces Support by Advisory Committee of The Office of Generic Drugs Proposed Guidelines for Developing Generic Versions of Oral Vancomycin Hydorchloride 2Health News:ViroPharma Announces Support by Advisory Committee of The Office of Generic Drugs Proposed Guidelines for Developing Generic Versions of Oral Vancomycin Hydorchloride 3Health News:ViroPharma Announces Support by Advisory Committee of The Office of Generic Drugs Proposed Guidelines for Developing Generic Versions of Oral Vancomycin Hydorchloride 4Health News:Premier of Split Estate at DocuWeeks 2009 to Call National Attention to Urban Drilling in New York and Los Angeles 2Health News:Premier of Split Estate at DocuWeeks 2009 to Call National Attention to Urban Drilling in New York and Los Angeles 3Health News:Clarient Reports Second Quarter Revenue Up 40 Percent 2Health News:Clarient Reports Second Quarter Revenue Up 40 Percent 3Health News:Clarient Reports Second Quarter Revenue Up 40 Percent 4Health News:Clarient Reports Second Quarter Revenue Up 40 Percent 5Health News:Clarient Reports Second Quarter Revenue Up 40 Percent 6Health News:Clarient Reports Second Quarter Revenue Up 40 Percent 7Health News:Clarient Reports Second Quarter Revenue Up 40 Percent 8Health News:Clarient Reports Second Quarter Revenue Up 40 Percent 9Health News:Clarient Reports Second Quarter Revenue Up 40 Percent 10Health News:Cambrex Reports Second Quarter 2009 Results 2Health News:Cambrex Reports Second Quarter 2009 Results 3Health News:Cambrex Reports Second Quarter 2009 Results 4Health News:Cambrex Reports Second Quarter 2009 Results 5Health News:Cambrex Reports Second Quarter 2009 Results 6Health News:Cambrex Reports Second Quarter 2009 Results 7Health News:Cambrex Reports Second Quarter 2009 Results 8Health News:Cambrex Reports Second Quarter 2009 Results 9Health News:Cambrex Reports Second Quarter 2009 Results 10Health News:Cambrex Reports Second Quarter 2009 Results 11Health News:Cambrex Reports Second Quarter 2009 Results 12Health News:FDA extends review of Pennsaid(R) diclofenac sodium topical solution 2Health News:FDA extends review of Pennsaid(R) diclofenac sodium topical solution 3Health News:Inverness Medical Innovations, Inc. Announces Offering of $150 Million of Senior Notes 2
(Date:9/30/2014)... NEW YORK , Sept. 30, 2014 /PRNewswire/ ... - 2014 Summary Global Markets Direct,s, ... 2014, provides an overview of the Arbor Pharmaceuticals, ... report provides comprehensive information on the current therapeutic ... comparative analysis at various stages, therapeutics assessment by ...
(Date:9/30/2014)... According to the ... Product [Enzymes (Glycosyltransferase, Neuraminidase, Glycosidase), Instruments (HPLC, ... (Immunology, Oncology) & by End User - ... provides a detailed overview of the major ... and strategies impacting the global glycomics enzymes, ...
(Date:9/30/2014)... , Sept. 30, 2014 Valeant Pharmaceuticals International, ... today announced that the company,s Bridgewater, New ... the U.S. Food and Drug Administration (FDA) relating to ... with regards to Sculptra Aesthetic injectable, which was divested ... to the management of Valeant,s contract manufacturers (rather than ...
Breaking Medicine Technology:Arbor Pharmaceuticals, LLC. - Product Pipeline Review - 2014 2Arbor Pharmaceuticals, LLC. - Product Pipeline Review - 2014 3Glycobiology / Glycomics Market Worth $928.11 Million by 2019 2Glycobiology / Glycomics Market Worth $928.11 Million by 2019 3Glycobiology / Glycomics Market Worth $928.11 Million by 2019 4Valeant Pharmaceuticals' Bridgewater Location Receives Warning Letter From FDA 2
... Screen Tests are available in 14 configurations ... Designed using Microgenics Antibody Technology, the SureStep™ ... of care immunoassay targeted to detect MDMA ... and MDEA but no cross-reactivity to any ...
... The InstaCheck® multi-drug test device ... and easily. Negative results can ... as 3 minutes; positive results ... simple, one-time urine sample application ...
Accu-Stat Home Drug Test for Marijuana (THC), Cocaine (COC), Amphetamine (AMP), Methamphetamine (mAMP), Opiates (OPI), and Phencyclidine (PCP)....
... onsite test! QuickScreen™ multi-panel dip cards offer ... your choice of any conceivable combination of ... flexibility for your drug testing program. Just ... the built-in timer tells you when to ...
Medicine Products: