Navigation Links
Study finds specific gene linked to cold sore susceptibility
Date:10/27/2011

Investigators have identified a human chromosome containing a specific gene associated with susceptibility to herpes simplex labialis (HSL), the common cold sore. Published in the Journal of Infectious Diseases and now available online, the study looks at how several genes may affect the severity of symptoms and frequency of this common infection. The findings, if confirmed, could have implications for the development of new drugs to treat outbreaks.

HSL outbreaks, or cold sores, are skin infections that appear with the reactivation of herpes simplex virus, a virus that infects 70 percent of the U.S. population. Cold sore outbreaks vary in frequency and severity; some people may experience symptoms rarely, only once every 5 to 10 years, while others may experience them once a month or even more frequently. In addition to investigating environmental activating factors (e.g., sunlight) that may play a role in outbreaks, researchers for some time have been looking at the possible role of genetic factors in virus susceptibility and activation.

This study, led by John D. Kriesel, MD, and colleagues from the University of Utah School of Medicine in Salt Lake City and the University of Massachusetts Medical School in Worcester, follows previous studies identifying a region of chromosome 21 as a base for genes possibly linked to cold sore outbreaks. To identify which of six possible genes in this region were associated with the frequency of outbreaks, this latest study used single nucleotide polymorphism genotyping in genome-wide, family-based linkage studies of 618 people from 43 large families. The investigators found a positive link between the frequency of outbreaks, hereditability, and the presence of a specific gene, C21orf91, on chromosome 21.

"While these findings await confirmation in a larger, unrelated population," the study authors note, "these findings could have important implications for the development of new drugs tha
'/>"/>

Contact: John Heys
jheys@idsociety.org
703-299-0412
Infectious Diseases Society of America
Source:Eurekalert

Page: 1 2

Related medicine news :

1. Poorer Countries Have Higher Rates of Stroke, Study Finds
2. NYUCN receives $299 thousand from NCSBN to study patient safety in nursing homes
3. Too Much Drinking May Raise Lung Cancer Risk: Study
4. X-Ray Screening Doesnt Prevent Lung Cancer Deaths: Study
5. HPV Vaccine Might Help Prevent Anal Cancers: Study
6. Links to Mental Illness Seen in Fetal Brains: Study
7. Religious, spiritual support benefits men and women facing chronic illness, MU study finds
8. Study identifies genetic basis of human metabolic individuality
9. Study indicates nanoparticles could help pain-relieving osteoarthritis drugs last longer
10. Study shows why underrepresented men should be included in binge eating research
11. Some Asthma Drugs Raise Risk of Complications, Especially in Kids: Study
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:12/17/2014)... -- Expectant parents should leave prenatal picture-taking to medical ... Use of ultrasound imaging and heartbeat monitors to get ... agency warns. "Although there is a lack ... and heartbeat monitors, prudent use of these devices by ... FDA biomedical engineer, said in an agency news release. ...
(Date:12/17/2014)... HealthDay Reporter , TUESDAY, Dec. 16, ... America, and work commitment is a big reason why, new ... said Dr. Mathias Basner, an assistant professor of sleep and ... of Medicine. A time-use survey of nearly 125,000 Americans, ... main activity exchanged for sleep. Short sleepers -- those who ...
(Date:12/15/2014)... 15, 2014 South Florida’s leading urgent care ... can be a daze of hassle, hustle, and bustle that ... decking halls, to burns when making special meals and heartburn ... can happen at any time. To prevent this season of ... made a list of helpful and healthful holiday tips to ...
(Date:12/15/2014)... News) -- Expert pilots process visual information more efficiently ... better decisions during landings, a new study shows. ... pilots to master, and 36 percent of all airplane ... final approach and landing. Researchers monitored the brain ... pilots while they were at the controls of a ...
(Date:12/15/2014)... 15, 2014 At the leading, long-established ... AutismOne and Focus Autism will welcome ... research on the effects of toxins to children’s health, ... information. , Luminaries such as Dr. Lucija Tomljenovic ... with esteemed, credentialed colleagues of the United States to ...
Breaking Medicine News(10 mins):Health News:FDA Warns Against Fetal 'Keepsake' Videos 2Health News:Work Steals Valuable Sleep Time, Study Finds 2Health News:Work Steals Valuable Sleep Time, Study Finds 3Health News:MD Now Urgent Care Presents Healthy Holiday Tips 2Health News:MD Now Urgent Care Presents Healthy Holiday Tips 3Health News:Study Shows Why Expert Pilots Are Experts 2Health News:AutismOne and Focus Autism Collaborate on Scientific Conference; International Group of Researchers to Present in Chicago, May 2015 2Health News:AutismOne and Focus Autism Collaborate on Scientific Conference; International Group of Researchers to Present in Chicago, May 2015 3
... Public Awareness and Research to Improve Medical Care for ... Observed Around the World With a Variety of Programs ... (Nasdaq: BMRN ) announced today that it ... the National Organization for Rare Disorders (NORD) to support ...
... Feb. 26 The Healthcare Businesswomen,s Association (HBA) today ... Worldwide Chairman, Surgical Care, and member of the Executive ... recognized at the 20th annual HBA "Woman of the ... event of the year for the healthcare community attended ...
... Feb. 26 Endo Pharmaceuticals (Nasdaq: ENDP ... to the company,s board of directors. Mr. Montague, ... of Mark IV Industries, retired in July last year. ... highly-engineered systems and components for the transportation, industrial and ...
... HILLS, Calif., Feb. 26 There are some people who seem ... on life, a sleek physique ... an all-around "glow." While it ... to their success is a tried-and-true model: set a goal and ... Healthy Life" (published by iUniverse) reveals that by applying ...
... 26 IDM Pharma, Inc.,(Nasdaq: IDMI ) ... Rare Disorders (NORD) and more than 100 patient organizations, ... observe,Rare Disease Day on February 28. The goal ... the challenges encountered by those affected and the importance,of ...
... 26 Apollo Health Street has earned the Number ... the prestigious Black Book of Outsourcing Customer Satisfaction Survey, ... states, "We appreciate the recognition from the Black Book ... customers. This is an independent validation of our commitment ...
Cached Medicine News:Health News:BioMarin Supports Observance of Rare Disease Day February 28 2Health News:BioMarin Supports Observance of Rare Disease Day February 28 3Health News:BioMarin Supports Observance of Rare Disease Day February 28 4Health News:Healthcare Businesswomen's Association Names Johnson & Johnson's Alex Gorsky, Worldwide Chairman, Surgical Care, as the 2009 HBA Honorable Mentor 2Health News:Healthcare Businesswomen's Association Names Johnson & Johnson's Alex Gorsky, Worldwide Chairman, Surgical Care, as the 2009 HBA Honorable Mentor 3Health News:Healthcare Businesswomen's Association Names Johnson & Johnson's Alex Gorsky, Worldwide Chairman, Surgical Care, as the 2009 HBA Honorable Mentor 4Health News:Endo Pharmaceuticals Appoints William Montague to Board of Directors 2Health News:Endo Pharmaceuticals Appoints William Montague to Board of Directors 3Health News:'I Count(TM): 10 Simple Steps to a Healthy Life': Time and Money-Strapped Americans Find Balance, Better Health with New Book 2Health News:'I Count(TM): 10 Simple Steps to a Healthy Life': Time and Money-Strapped Americans Find Balance, Better Health with New Book 3Health News:IDM Pharma Joins NORD to Raise Awareness of Rare Diseases 2Health News:IDM Pharma Joins NORD to Raise Awareness of Rare Diseases 3Health News:IDM Pharma Joins NORD to Raise Awareness of Rare Diseases 4Health News:Apollo Health Street Has Earned the Number One Spot in the BPO Healthcare Providers Segment in the Prestigious Black Book of Outsourcing Customer Satisfaction Survey, 2008 2
(Date:12/17/2014)... Tenn. , Dec. 17, 2014  Strategic Health ... management software solutions, today announced a strategic agreement with ... New Jersey regional marketplace.  This ... enhance the health and wellness solutions QualCare brings to ... and the surrounding region. QualCare plans ...
(Date:12/17/2014)... , December 17, 2014 ... less than a hub of information concerning the biopharmaceutical Group,s ... A further addition to the recently launched institutional website ... has now been enriched by a new chapter in the ... A richly detailed and panoramic hub on the world ...
(Date:12/17/2014)... RALEIGH, N.C. , Dec. 17, ... (CTMC), and Integrated Clinical Trial Services, LLC (ICTS), ... for clinical trials announce that they have formed ... Services (i-CTMS). i-CTMS will provide a broad range ... biotechnology and medical device companies. i-CTMS ...
Breaking Medicine Technology:Strategic Health Services to collaborate with QualCare on Population Health and Wellness Technology for QualCare Members 2Strategic Health Services to collaborate with QualCare on Population Health and Wellness Technology for QualCare Members 3Dompé Offers a New "Window" on the World of Scientific Research, with the http://www.dompetrials.com Website, Dedicated to Clinical Trials 2Dompé Offers a New "Window" on the World of Scientific Research, with the http://www.dompetrials.com Website, Dedicated to Clinical Trials 3Integrated Clinical Trial Services and Clinical Trial Marketing Communications Form Joint Venture 2Integrated Clinical Trial Services and Clinical Trial Marketing Communications Form Joint Venture 3
... SurgiFrost is a malleable, single-use cryosurgical ... open-heart surgery. The probe will ablate cardiac ... primary cardiac surgical procedure, such as coronary ... (MV) replacement and/or repair and as part ...
The Medtronic StableMapr catheter is intended for use in diagnostic electrophysiologic procedures. These catheters are designed for recording intracardiac electrograms and temporary pacing associated...
The Valve Mapper Steerocath-Dx has a unique "peanut" shaped tip. It is designed to conform to the anatomy during mapping procedures. Both 8F/8mm and 8F/6mm tips are available....
... designed for use with our CARTO EP ... catheter houses a Biosense Webster sensor at ... time, exact location points from within the ... The NAVI-STAR electro-anatomical navigation catheter is used ...
Medicine Products: